Development of a minimal saponin vaccine adjuvant based on QS-21

The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans

(2014) Kenneth Von Eschen et al.   Human vaccines & immunotherapeutics

Modern Subunit Vaccines: Development, Components, and Research Opportunities

(2013) Peter Michael Moyle et al.   ChemMedChem

Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes

(2012) Eric K. Chea et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

(2011) Govind Ragupathi et al.   Expert Review of Vaccines

ISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cells In Vivo Leading to Effective Cross-Priming of CD8+ T Cells

(2011) P. Duewell et al.   JOURNAL OF IMMUNOLOGY

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

(2011) Samuele Calabro et al.   VACCINE

Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines

(2011) Nathaly Castro-Díaz et al.   VACCINE

Design and Synthesis of PotentQuillajaSaponin Vaccine Adjuvants

(2010) Michelle M. Adams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unmet needs in modern vaccinology

(2010) Geert Leroux-Roels   VACCINE

Long-Term Follow-Up of Patients Immunized with AN1792: Reduced Functional Decline in Antibody Responders

(2009) Bruno Vellas et al.   Current Alzheimer Research

Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine

(2008) Kai Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY

The safety and tolerability of an HIV-1 DNA prime–protein boost vaccine (DP6-001) in healthy adult volunteers

(2008) Jeffrey S. Kennedy et al.   VACCINE

Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers

(2008) Pierre Vandepapelière et al.   VACCINE