Sub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate

Specificity in Transition State Binding: The Pauling Model Revisited

(2013) Tina L. Amyes et al.   BIOCHEMISTRY

Enhanced rigid-bond restraints

(2012) Andrea Thorn et al.   ACTA CRYSTALLOGRAPHICA SECTION A

Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C–C Bond Cleavage

(2011) Dalibor Milić et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming lability of extremely long alkane carbon–carbon bonds through dispersion forces

(2011) Peter R. Schreiner et al.   NATURE

Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism

(2011) Anja Lehwess-Litzmann et al.   Nature Chemical Biology

The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action

(2010) Lars Mitschke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thiamin Diphosphate Catalysis: Enzymic and Nonenzymic Covalent Intermediates

(2008) Ronald Kluger et al.   CHEMICAL REVIEWS

Non-charged thiamine analogs as inhibitors of enzyme transketolase

(2007) Allen A. Thomas et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS