The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action

Metabolic genes in cancer: Their roles in tumor progression and clinical implications

(2010) Eiji Furuta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

TKTL1 Is Activated by Promoter Hypomethylation and Contributes to Head and Neck Squamous Cell Carcinoma Carcinogenesis through Increased Aerobic Glycolysis and HIF1  Stabilization

(2010) W. Sun et al.   CLINICAL CANCER RESEARCH

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

(2010) F Zhao et al.   ONCOGENE

Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance

(2009) Young-Kyoung Shin et al.   ELECTROPHORESIS

X-ray crystallographic snapshots of reaction intermediates in pyruvate oxidase and transketolase illustrate common themes in thiamin catalysis

(2009) Kai Tittmann et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency

(2009) Yanling Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS

Thiamin Diphosphate Catalysis: Enzymic and Nonenzymic Covalent Intermediates

(2008) Ronald Kluger et al.   CHEMICAL REVIEWS

Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells

(2008) Xiaojun Xu et al.   INTERNATIONAL JOURNAL OF CANCER

Preparative scale enzymatic synthesis of d-sedoheptulose-7-phosphate from β-hydroxypyruvate and d-ribose-5-phosphate

(2008) Franck Charmantray et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers

(2008) Shuqing Liu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Non-charged thiamine analogs as inhibitors of enzyme transketolase

(2007) Allen A. Thomas et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors

(2007) Allen A. Thomas et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Prodrug thiamine analogs as inhibitors of the enzyme transketolase

(2007) Yvan Le Huerou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS