Review
Engineering, Chemical
Luana M. Rosendo, Ana Teresa Brinca, Bruno Pires, Goncalo Catarro, Tiago Rosado, Raquel P. F. Guine, Andre R. T. S. Araujo, Ofelia Anjos, Eugenia Gallardo
Summary: Natural products are widely used in industry, food, and therapy. Characterizing them chemically is vital to explore their potential applications. Microextraction techniques, which use less organic solvents and sample amount compared to classical techniques, have gained popularity but are still less used in natural product analysis. This manuscript reviews popular solid-based miniaturized sample preparation techniques and discusses their advantages, disadvantages, and main applications in determining compounds in natural products.
Article
Chemistry, Analytical
Lidia Akemi Akamine, Deyber Arley Vargas Medina, Fernando Mauro Lancas
Summary: In this study, a graphene oxide/magnetite (GO-Fe3O4) nanocomposite was synthesized and utilized in the magnetic solid-phase extraction (MSPE) of gingerols from various ginger products. The developed MSPE method combined with HPLC-MS/MS analysis demonstrated high selectivity and consistent analytical confidence, with LODs ranging between 2 and 3 μg L-1. The technique showed good linearity, accuracy, and practicality, making it a valuable tool for quality control of commercial ginger-containing products.
Review
Biochemistry & Molecular Biology
Mirian Pateiro, Julian Andres Gomez-Salazar, Mariana Jaime-Patlan, Maria Elena Sosa-Morales, Jose M. Lorenzo
Summary: Plants are rich in bioactive compounds such as polyphenols, which can replace synthetic antioxidants in meat products. These natural antioxidants, obtained from fruits, vegetables, herbs, and spices, contribute to the quality of meat products and offer benefits in terms of environmental protection and resource reutilization.
Review
Acoustics
Arthur Luiz Baiao Dias, Ana Carolina de Aguiar, Mauricio A. Rostagno
Summary: This study provides a comprehensive assessment of high-pressure systems, specifically supercritical fluid extraction and pressurized liquid extraction assisted by ultrasound, as emerging technologies for extracting bioactive compounds from natural products. The extraction mechanisms, applications, and the influence of operational parameters in the process are addressed, along with an analysis of the main challenges for widespread application.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Gema Casado-Hidalgo, Gonzalo Martinez-Garcia, Sonia Morante-Zarcero, Damian Perez-Quintanilla, Isabel Sierra
Summary: An efficient and simple method was developed and validated for the analysis of six opium alkaloids in bakery products. The method showed adequate recoveries, low standard deviations, and no matrix effects. The study also revealed that some bakery products contained opium alkaloids exceeding the regulated standard.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Pharmacology & Pharmacy
Qinfang Zheng, Ye Wang, Shuihan Zhang
Summary: This work reviews the progress in the phytochemical and biological investigations of bioactive components from Lobelia species, highlighting the shift in research focus towards novel chemical classes and molecular mechanisms of these components.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Katarzyna Godlewska, Pawel Pacyga, Agnieszka Najda, Izabela Michalak
Summary: The aim of this publication is to propose rapid screening methods for the identification of biologically active compounds in aqueous solutions. Plant extracts obtained by ultrasound-assisted extraction were analyzed for the content of these compounds. Initial characterization using fast and inexpensive methods allows for avoiding time-consuming analyses with advanced research equipment. Additionally, the antioxidant activity and quantitative analysis of plant hormones were performed.
Review
Polymer Science
Sazlinda Kamaruzaman, Najihah Mohammad Nasir, Siti Munirah Mohd Faudzi, Noorfatimah Yahaya, Nor Suhaila Mohamad Hanapi, Wan Nazihah Wan Ibrahim
Summary: MIPs, synthetic polymers with predetermined selectivity, are ideal for separation processes and have been widely studied in natural product applications.
Article
Plant Sciences
Tao Tao, Ping Zhang, Zhi Zeng, Min Wang
Summary: Natural products have a critical role in drug development, especially in cancer therapy. There is increasing evidence that many natural products may modulate autophagy in cervical cancer. Understanding the mechanisms of these natural products helps to develop medications for cervical cancer treatments.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Florian Kaltner
Summary: Toxic plant alkaloids (TPAs) found in food may be affected by storing or processing, leading to decreased levels of the parent alkaloids. However, little is known about potential transformation products and their toxic potential. This perspective summarizes the current knowledge on the behavior of opium, pyrrolizidine, and tropane alkaloids during processing or storing, and highlights analytical strategies to identify and elucidate potential transformation products.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Polymer Science
Huan An, Xuehui Deng, Fang Wang, Pingcui Xu, Nani Wang
Summary: Natural products have shown their therapeutic value in treating various diseases, but their low solubility and poor bioavailability present challenges. To overcome these issues, drug nanocarriers, particularly dendrimers, have been developed. This review summarizes the structures of dendrimer-based nanocarriers and their applications in alkaloids and polyphenols, while also discussing future challenges and perspectives in clinical therapy.
Article
Chemistry, Applied
Zhixin Xiao, Min Liu, Wentao Bi, David Da Yong Chen
Summary: In-depth studies of extraction mechanism using deep eutectic solvents (DES) and ionic liquids (IL) reveal similarities between the two systems. New applications of ILs and DES in the extraction of nutritional natural products are presented. The study systematically investigates the extraction behavior of ChCl and [HMIm][Cl] in DES and IL, respectively, for target compound extraction from Moringa oleifera leaves. The results show that both extraction methods are based on the formation of a DESys, which can be improved by the formation of a new IL deep eutectic system based on hydrogen bond interaction.
Review
Chemistry, Multidisciplinary
A. O. Adeeyo, J. A. Oyetade, M. A. Alabi, R. O. Adeeyo, A. Samie, R. Makungo
Summary: The environmental impact and denaturing propensity of organic solvents are challenges in the extraction of plant bioactives. Tuning water properties offers a greener and efficient alternative with high yield and preserved bioactivities.
Review
Biochemistry & Molecular Biology
Yan Cheng, Fumin Xue, Shuai Yu, Shichao Du, Yu Yang
Summary: Subcritical water extraction (SBWE) utilizes high-temperature and high-pressure water to extract natural products, offering advantages in eco-friendliness, safe disposal, and tunable properties for selective extractions. Temperature optimization is key to efficiency, and different co-solvents can be used to enhance extraction of certain compounds.
Article
Chemistry, Analytical
Xiaobing Liu, Pan Wang, Kai Hu, Lixin Li, Cheng Yang, Zhihong Chen, Huahui Zeng, Zhenqiang Zhang
Summary: A borate hyper-crosslinked polymer was synthesized via the Friedel-Crafts reaction, demonstrating excellent adsorption performance for alkaloids and polyphenols. The method allowed for the simultaneous quantification of these compounds in green tea and Coptis chinensis, with a wide linear range, low detection limit, and satisfactory recoveries. This study provides a simple and convenient approach for the sensitive determination of alkaloids and polyphenols in green tea and complex herbal products.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Konstantza Tonova, Milen G. Bogdanov
SEPARATION SCIENCE AND TECHNOLOGY
(2017)
Article
Chemistry, Multidisciplinary
Ivan Svinyarov, Rozalina Keremedchieva, Milen G. Bogdanov
SEPARATION SCIENCE AND TECHNOLOGY
(2016)
Article
Chemistry, Multidisciplinary
Ivan Svinyarov, Milen G. Bogdanov
SEPARATION SCIENCE AND TECHNOLOGY
(2018)
Article
Engineering, Chemical
Milen G. Bogdanov, Ivan Svinyarov
Article
Biochemical Research Methods
Milen G. Bogdanov, Ivan Svinyarov
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Engineering, Chemical
Milen G. Bogdanov, Ivan Svinyarov
SEPARATION AND PURIFICATION TECHNOLOGY
(2018)
Article
Chemistry, Physical
Magdalena Bendova, Maja Canji, Zdenek Wagner, Milen G. Bogdanov
JOURNAL OF SOLUTION CHEMISTRY
(2019)
Article
Chemistry, Physical
Maja Canji, Magdalena Bendova, Milen G. Bogdanov, Zdenek Wagner, Nikola Zdolsek, Francois Quirion, Vera Jandova, Pavel Vrbka
JOURNAL OF MOLECULAR LIQUIDS
(2019)
Article
Chemistry, Physical
Magdalena Bendova, Zdenek Wagner, Milen G. Bogdanov, Maja Canji, Nikola Zdolsek
JOURNAL OF MOLECULAR LIQUIDS
(2020)
Article
Engineering, Chemical
Iva Belovezhdova, Boyan Todorov, Milen G. Bogdanov
Summary: The study explores the use of a hydrophobic but polar ionic liquid (IL) in liquid-liquid extraction for the recovery of radioactive elements and investigates the factors influencing the extraction yield. Different behavior of radionuclides under the same conditions is attributed to the formation of species capable of interacting with the IL. A simple procedure for extraction and concentration of radioactive elements is developed based on the results obtained.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
N. Kaneva, A. Bojinova, K. Papazova, D. Dimitrov, I. Svinyarov, M. Bogdanov
BULGARIAN CHEMICAL COMMUNICATIONS
(2015)
Article
Engineering, Chemical
Yunfei Yu, Xue Yang, Chenchen Zhang, Jie Chen, Wei Lin, Jianqiang Meng
Summary: This study reports an environmentally friendly and simple approach for preparing double-network (DN) ion gel membranes with high strength and excellent gas separation performance. By optimizing crosslinking density, mass ratio, and the type and content of free ionic liquid, the mechanical and gas separation properties of the DN membrane are improved.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Si-qi Jiang, Qiang Gao, Xi-guang Li, Chao-zhu Deng, Jun Qiu, Xiang-nan Zhu
Summary: A dual-strengthening pretreatment method is proposed to remove PVDF more efficiently and enhance the leaching of LiCoO2. Experimental results show that dual-strengthening pretreatment can effectively remove PVDF and significantly improve the leaching efficiency compared to single pretreatment methods.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Zengchi Hu, Xiaoyu Wang, Xiaohui Zhang, Xue Li, Jiangbin Xia
Summary: The rapid fabrication of high-performance composite membranes based on CMPs using simple and low-cost methods is challenging. In this study, three CMPs-based composite membranes were rapidly fabricated with adjustable size using unidirectional diffusion synthesis. The microstructural design enhanced the rejection rates of the membranes and they showed strong hydrolytic resistance, thermal stability, and acid-base resistance. Electrostatic adsorption and the adjustable microstructures significantly varied the repellence of the membranes to different charged molecules.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Farzaneh Rouhani, Matineh Ayedi, Nasser Safari
Summary: Introducing defects into porous metal-organic frameworks is important for improving their adsorption performance. Quasi-MOFs, an underutilized variant of large-scale, fundamentally deficient MOFs, have been found to have substantial amounts of unsaturated metal sites to offset the drawbacks of MOFs. In this study, a quasi-MOF was produced using a water-stable MOF and demonstrated significantly improved phosphate adsorption capability due to the presence of defect sites.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Valentin Reungoat, Morad Chadni, Louis M. M. Mouterde, Fanny Brunissen, Florent Allais, Helene Ducatel, Irina Ioannou
Summary: This study focuses on the recovery of sinapic acid using liquid-liquid extraction assisted by a hollow fiber membrane contactor from an aqueous feed obtained through the hydrolysis of mustard bran. The screening of solvents of different chemical nature showed that all tested solvents had an extraction efficiency of more than 80% for pH < 5. Four solvents were selected for use in the hollow fiber membrane contactor, and the volatile solvents showed higher mass transfer coefficients compared to non-volatile solvents. The extraction efficiency was intensified by increasing the initial concentration of sinapic acid and the feed-to-solvent ratio. CPME was found to have optimal recovery efficiency at a phase ratio of 8:1, yielding 0.9 g of sinapic acid per liter of CPME used.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Takahiro Sakamoto, Takafumi Hanada, Hayate Sato, Mayu Kamisono, Masahiro Goto
Summary: The emergence of the battery society has led to a high demand for battery metals, resulting in a strain on their supply. This study introduces a novel technique using a hydrophobic deep eutectic solvent (DES) for leaching and recovering battery metals from low-grade nickel laterite ores. The DES enables selective leaching and recovery of the metals, offering a promising pathway for the extraction of critical battery metals.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Rongrong He, Jiarui Chen, Chunyao Zhang, Dan Lu, Lin Zhang, Tao He
Summary: Researcher has developed a method to quantify the charge density in nanofiltration (NF) membrane separation layer and applied it in NF membranes that can separate Mg2+ and Li+. The results showed that overcompensated amine groups played a major role, and there was a linear relationship between charge density and coating bi-layers or PAH layers.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Zhijian Zhang, Min Chen, Zhe Lin, Zhichao Yang, Yafeng Du, Zhihui Chen, Zhenhao Yang, Kongyin Zhao, Ligang Lin
Summary: Membrane technology plays an important role in molecular/ion separation processes, but faces challenges such as membrane fouling. This study introduces a new ion-crosslinking method to fabricate copper alginate hydrogel membranes with improved mechanical strength and antimicrobial capabilities. The membranes exhibit excellent separation performance and enhanced long-term molecule/ion separation through improved anti-swelling properties. Molecular dynamics simulations and life cycle analysis highlight the pore structure and environmental friendliness of the hydrogel membranes. These findings provide valuable insights for developing sustainable hydrogel membranes with stable performance and high separation efficiency.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Dongmei Liu, Aiying Guo, Yanling Qi, Zhixin Ji, Hongjuan Li, Zhiwei Zhang, Xinyue Zhang, Kunze Wu, Aijun Cai
Summary: In this study, a stable magnetic Mg/Mn-layered double oxide-doped biochar composite (MgMnLDO-MBC) was prepared and successfully used for the removal of antibiotics and bacteria from wastewater. The composite exhibited enhanced surface areas, adsorption sites, and free radicals, leading to improved catalytic activity. The effects of different factors on the removal efficiency were evaluated, and the composite showed good reusability.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Feng Wang, Zhaoyong Bian, Yaru Zhang, Wenchao Yu, Qiang Zhang, Hui Wang
Summary: In this study, a nanofibrous layered structure of Ff-Ti3C2Tx-Co3O4 was prepared by self-assembling nanofibrous Co3O4 with lamellar fluorine-free MXene (Ff-Ti3C2Tx). The Ff-Ti3C2Tx-Co3O4 exhibited excellent catalytic activity for degradation, resistant to ionic interference, and maintained high removal efficiency of sulfamethoxazole (SMX) in municipal wastewater. The rapid SMX degradation involved fast electron transfer in redox cycles with PMS and the generation of 1O2 via PMS ->center dot O2 -> 1O2. This work provides new insights into antibiotic degradation mechanisms and electron transfer based on PMS activation.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Weipeng He, Jiacheng Luo, Yujie Wu, Tianhao Luo, Chen Tang
Summary: This study comparatively evaluated the role of cationic, anionic, and nonionic polyacrylamides (PAMs) in ballasted flocculation of clay suspensions under different aluminum sulfate (AS) coagulant dosages. The selection of PAMs and AS dosage had a significant influence on the size and shear resistance of ballasted floc aggregates.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Lixian Wang, Lizhi Zhao, Didi Si, Zhixin Li, Huiqin An, Hui Ye, Qingping Xin, Hong Li, Yuzhong Zhang
Summary: Metalloporphyrin-based nanozymes integrated with poly (vinylidene fluoride) membrane show high catalytic activity and reusability for the decolorization of Congo Red dye in continuous flow process.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Yongfei Ma, Chenyu Zeng, Yongzhen Ding, Jiayi Tang, Ondrej Masek, Zhikang Deng, Rui Mu, Zulin Zhang
Summary: In this study, sludge-derived biochar (SBC) was functionalized with various iron salts to enhance its adsorption ability for sulfamethoxazole (SMX) and magnetic collection performance. Ball milling was further employed to treat the optimal iron salt functionalized SBC (MSBC), resulting in ball milled SBC (BMSBC) with improved adsorption performance for SMX. The dominant driving mechanism for SMX adsorption onto BMSBC was confirmed to be multiple physicochemical forces, including 7C-7C conjugation, pore filling, H-bonding, Fe-O complexation, and electrostatic interactions. BMSBC exhibited favorable adsorption ability for SMX in actual waters and could be easily collected within 1 min due to its magnetic sensitivity.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Jinglin Tan, Xiaohui Mao, Wenjihao Hu, Hongbo Zeng
Summary: This study investigates the influence of PDMS chain architectures on surface properties and reveals that PDMS coatings with looped structures exhibit superior hydrophobicity, self-cleaning, and water sliding compared to coatings with linear structures. Additionally, both looped and linear PDMS coated stainless steel mesh/polyester fibers show efficient separation of oil/water mixture.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Engineering, Chemical
Wei-Liang Chen, Chih-Chia Cheng, Chien-Hsing Lu, Jem-Kun Chen
Summary: This study designs a novel sandwich-structured capacitor that reduces the absorption time of pollutants using dielectrophoresis force. By coating graphene oxide on polystyrene microspheres as adsorbents and encapsulating them within the capacitor, the adsorption rate is significantly enhanced. Additionally, frequency manipulation allows for the recycling of adsorbents and concentration of dyes, minimizing secondary pollution.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)