Quantification of nanoparticles at the single-cell level: an overview about state-of-the-art techniques and their limitations

Imaging macrophages with nanoparticles

(2014) Ralph Weissleder et al.   NATURE MATERIALS

Encoded Particles: Fluorescence-Encoded Gold Nanoparticles: Library Design and Modulation of Cellular Uptake into Dendritic Cells (Small 7/2014)

(2014) Laura Rodriguez-Lorenzo et al.   Small

Precise Quantification of Nanoparticle Internalization

(2013) Claudia Gottstein et al.   ACS Nano

Quantification of ZnO Nanoparticle Uptake, Distribution, and Dissolution within Individual Human Macrophages

(2013) Simon A. James et al.   ACS Nano

ICP-MS-based characterization of inorganic nanoparticles—sample preparation and off-line fractionation strategies

(2013) Anne-Lena Fabricius et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nanoparticles: a global vision. Characterization, separation, and quantification methods. Potential environmental and health impact

(2013) Ana López-Serrano et al.   Analytical Methods

A high-throughput framework to detect synapses in electron microscopy images

(2013) S. Navlakha et al.   BIOINFORMATICS

Quantification of the Uptake of Silver Nanoparticles and Ions to HepG2 Cells

(2013) Su-juan Yu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bending the Rules: Widefield Microscopy and the Abbe Limit of Resolution

(2013) Jolien S. Verdaasdonk et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Surface-Enhanced Raman Scattering Dye-Labeled Au Nanoparticles for Triplexed Detection of Leukemia and Lymphoma Cells and SERS Flow Cytometry

(2013) Christina M. MacLaughlin et al.   LANGMUIR

A palladium label to monitor nanoparticle-assisted drug delivery of a photosensitizer into tumor spheroids by elemental bioimaging

(2013) Ann-Christin Niehoff et al.   Metallomics

Quantification of gold nanoparticle cell uptake under controlled biological conditions and adequate resolution

(2013) Barbara Rothen-Rutishauser et al.   Nanomedicine

A quantitative study of exocytosis of titanium dioxide nanoparticles from neural stem cells

(2013) Yanli Wang et al.   Nanoscale

Application of low-energy scanning transmission electron microscopy for the study of Pt-nanoparticle uptake in human colon carcinoma cells

(2013) Holger Blank et al.   Nanotoxicology

The Toxicity of Silver Nanoparticles Depends on Their Uptake by Cells and Thus on Their Surface Chemistry

(2013) Encarnación Caballero-Díaz et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Uptake of poly(2-hydroxypropylmethacrylamide)-coated gold nanoparticles in microvascular endothelial cells and transport across the blood–brain barrier

(2013) Christian Freese et al.   Biomaterials Science

Neuronal cells loaded with PEI-coated Fe3O4 nanoparticles for magnetically guided nerve regeneration

(2013) M. Pilar Calatayud et al.   Journal of Materials Chemistry B

Mesoporous silica nanoparticle-based cisplatin prodrug delivery and anticancer effect under reductive cellular environment

(2013) Byungjun Ahn et al.   Journal of Materials Chemistry B

Quantitative measurement of intracellular transport of nanocarriers by spatio-temporal image correlation spectroscopy

(2013) S Coppola et al.   Methods and Applications in Fluorescence

Intracellular SPIO labeling of microglia: high field considerations and limitations for MR microscopy

(2012) Jens T. Rosenberg et al.   Contrast Media & Molecular Imaging

Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells

(2012) Christian Freese et al.   Particle and Fibre Toxicology

Modern Micro and Nanoparticle-Based Imaging Techniques

(2012) Marketa Ryvolova et al.   SENSORS

Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells

(2012) Juan A Varela et al.   JOURNAL OF NANOBIOTECHNOLOGY

SERS labels for quantitative assays: application to the quantification of gold nanoparticles uptaken by macrophage cells

(2011) Vincenzo Amendola et al.   Analytical Methods

Detecting nanoparticulate silver using single-particle inductively coupled plasma-mass spectrometry

(2011) Denise M. Mitrano et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Quantification of nanoparticle uptake by cells using an unbiased sampling method and electron microscopy

(2011) Andreas Elsaesser et al.   Nanomedicine

Biomedical nanoparticles modulate specific CD4+T cell stimulation by inhibition of antigen processing in dendritic cells

(2011) Fabian Blank et al.   Nanotoxicology

Quantifying the biodistribution of nanoparticles

(2011) Yasuo Tsutsumi et al.   Nature Nanotechnology

Monitoring the Uptake and Redistribution of Metal Nanoparticles during Cell Culture Using Surface-Enhanced Raman Scattering Spectroscopy

(2010) Narayana M. S. Sirimuthu et al.   ANALYTICAL CHEMISTRY

Is Length an Appropriate Estimator to Characterize Pulmonary Alveolar Capillaries? A Critical Evaluation in the Human Lung

(2010) Christian Mühlfeld et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Influence of cell-internalization on relaxometric, optical and compositional properties of targeted paramagnetic quantum dot micelles

(2010) L.W.E. Starmans et al.   Contrast Media & Molecular Imaging

Detection of TiO2 nanoparticles in cells by flow cytometry

(2010) R. M. Zucker et al.   CYTOMETRY PART A

Quantification of nanoparticle uptake by cells using microscopical and analytical techniques

(2010) Andreas Elsaesser et al.   Nanomedicine

Intracellular imaging of nanoparticles: Is it an elemental mistake to believe what you see?

(2010) Christina Brandenberger et al.   Particle and Fibre Toxicology

Fluorescent-Magnetic Hybrid Nanoparticles Induce a Dose-Dependent Increase in Proinflammatory Response in Lung Cells in vitro Correlated with Intracellular Localization

(2010) Andrea D. Lehmann et al.   Small

Quantitative Evaluation of Cellular Uptake and Trafficking of Plain and Polyethylene Glycol-Coated Gold Nanoparticles

(2010) Christina Brandenberger et al.   Small

A systematic random sampling scheme optimized to detect the proportion of rare synapses in the neuropil

(2009) Nuno Maçarico da Costa et al.   JOURNAL OF NEUROSCIENCE METHODS

Intracellular Distribution of Macrophage Targeting Ferritin-Iron Oxide Nanocomposite

(2008) Masaki Uchida et al.   ADVANCED MATERIALS

A review of recent methods for efficiently quantifying immunogold and other nanoparticles using TEM sections through cells, tissues and organs

(2008) Terry M. Mayhew et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

ICP-MS: a powerful technique for quantitative determination of gold nanoparticles without previous dissolving

(2008) R. Allabashi et al.   JOURNAL OF NANOPARTICLE RESEARCH

The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line

(2008) Martin J.D. Clift et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY