Cell-based drug delivery systems for biomedical applications

Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore

(2018) Thinzar M. Lwin et al.   ANNALS OF SURGICAL ONCOLOGY

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

(2018) Yu Zhang et al.   NANO LETTERS

Bacteria-Mediated Tumor Therapy Utilizing Photothermally-Controlled TNF-α Expression via Oral Administration

(2018) Jin-Xuan Fan et al.   NANO LETTERS

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

(2018) Junnan Tang et al.   Nature Biomedical Engineering

Inflammatory Monocytes Loading Protease-Sensitive Nanoparticles Enable Lung Metastasis Targeting and Intelligent Drug Release for Anti-Metastasis Therapy

(2017) Xinyu He et al.   NANO LETTERS

Cancer therapy: Neutrophils traffic in cancer nanodrugs

(2017) Satoru Osuka et al.   Nature Nanotechnology

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

(2017) Peter Popp Wibroe et al.   Nature Nanotechnology

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

(2017) Leore T. Geller et al.   SCIENCE

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

(2017) Juli R. Bagó et al.   Science Translational Medicine

Mechanoresponsive stem cells to target cancer metastases through biophysical cues

(2017) Linan Liu et al.   Science Translational Medicine

Enhanced Blood Suspensibility and Laser-Activated Tumor-specific Drug Release of Theranostic Mesoporous Silica Nanoparticles by Functionalizing with Erythrocyte Membranes

(2017) Jinghan Su et al.   Theranostics

Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy

(2017) Yihui Zhai et al.   Theranostics

Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles

(2017) Chun Zhang et al.   Theranostics

In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy

(2017) Chao Wang et al.   Nature Biomedical Engineering

Targeted delivery of doxorubicin by nano-loaded mesenchymal stem cells for lung melanoma metastases therapy

(2017) Yuekui Zhao et al.   Scientific Reports

Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer

(2016) Haiqiang Cao et al.   ACS Nano

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

(2016) Quanyin Hu et al.   ADVANCED MATERIALS

Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery

(2016) Ran Mo et al.   Materials Today

Bacteria-Mediated Hypoxia-Specific Delivery of Nanoparticles for Tumors Imaging and Therapy

(2016) Cheng-Hung Luo et al.   NANO LETTERS

Synchronized cycles of bacterial lysis for in vivo delivery

(2016) M. Omar Din et al.   NATURE

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions

(2016) Ouajdi Felfoul et al.   Nature Nanotechnology

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma

(2015) Yuanyuan Guo et al.   ACS Nano

Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection

(2015) Dafeng Chu et al.   ACS Nano

Hydrogel Retaining Toxin-Absorbing Nanosponges for Local Treatment of Methicillin-ResistantStaphylococcus aureusInfection

(2015) Fei Wang et al.   ADVANCED MATERIALS

Anticancer Platelet-Mimicking Nanovehicles

(2015) Quanyin Hu et al.   ADVANCED MATERIALS

Anisamide-Decorated pH-Sensitive Degradable Chimaeric Polymersomes Mediate Potent and Targeted Protein Delivery to Lung Cancer Cells

(2015) Ling Lu et al.   BIOMACROMOLECULES

Red Blood Cell Population Dynamics

(2015) John M. Higgins   CLINICS IN LABORATORY MEDICINE

Synergistically Enhanced Therapeutic Effect of a Carrier-Free HCPT/DOX Nanodrug on Breast Cancer Cells through Improved Cellular Drug Accumulation

(2015) Fei Chen et al.   MOLECULAR PHARMACEUTICS

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Cell or Cell Membrane-Based Drug Delivery Systems

(2015) Songwei Tan et al.   Theranostics

Cationic Conjugated Polymer/Fluoresceinamine-Hyaluronan Complex for Sensitive Fluorescence Detection of CD44 and Tumor-Targeted Cell Imaging

(2014) Yanqin Huang et al.   ACS Applied Materials & Interfaces

Neural Stem Cell-Mediated Intratumoral Delivery of Gold Nanorods Improves Photothermal Therapy

(2014) Rachael Mooney et al.   ACS Nano

Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy

(2014) Vipul Gujrati et al.   ACS Nano

Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery

(2014) Bryan Ronain Smith et al.   Nature Nanotechnology

Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils

(2014) Zhenjia Wang et al.   Nature Nanotechnology

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Nanoparticle-detained toxins for safe and effective vaccination

(2013) Che-Ming J. Hu et al.   Nature Nanotechnology

A biomimetic nanosponge that absorbs pore-forming toxins

(2013) Che-Ming J. Hu et al.   Nature Nanotechnology

Silica Nanorattle–Doxorubicin-Anchored Mesenchymal Stem Cells for Tumor-Tropic Therapy

(2011) Linlin Li et al.   ACS Nano

Cell-Based Drug Delivery Devices Using Phagocytosis-Resistant Backpacks

(2011) Nishit Doshi et al.   ADVANCED MATERIALS

Elimination of blood group antigens: hope and reality

(2011) Claude Bagnis et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cell-mediated drug delivery

(2011) Elena V Batrakova et al.   Expert Opinion on Drug Delivery

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Mesenchymal Stem Cell Tumor-Homing: Detection Methods in Disease Model Systems

(2011) Michaela R. Reagan et al.   STEM CELLS

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles

(2010) Matthias T Stephan et al.   NATURE MEDICINE

Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging

(2009) Hui Wang et al.   STEM CELLS

Tumor-Targeted Interferon-α Delivery by Tie2-Expressing Monocytes Inhibits Tumor Growth and Metastasis

(2008) Michele De Palma et al.   CANCER CELL