Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses

Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells

(2014) A. L. Seager et al.   MUTAGENESIS

The reconstructed skin micronucleus assay in EpiDerm™: Reduction of false-positive results – a mechanistic study with epigallocatechin gallate

(2013) Katsuyuki Yuki et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

(2013) Adam D. Thomas et al.   TOXICOLOGICAL SCIENCES

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement

(2012) Paul Fowler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay

(2012) Marilyn J. Aardema et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance

(2012) Anna L. Seager et al.   TOXICOLOGICAL SCIENCES

Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure

(2010) A. Rossnerova et al.   MUTAGENESIS

In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models

(2010) M. Kirsch-Volders et al.   MUTAGENESIS

The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: Detailed protocol and harmonized scoring atlas

(2010) Erica L. Dahl et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Xenobiotic metabolism gene expression in the EpiDerm™ in vitro 3D human epidermis model compared to human skin

(2010) T. Hu et al.   TOXICOLOGY IN VITRO

Reaction Kinetics of Acetone Peroxide Formation and Structure Investigations Using Raman Spectroscopy and X-Ray Diffraction

(2009) L. Jensen et al.   APPLIED SPECTROSCOPY

Intralaboratory and interlaboratory evaluation of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay

(2009) Ting Hu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay

(2009) Greg C. Mun et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose–response relationships, exemplified for mutagenicity data

(2009) Werner K. Lutz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: Application of the EpiDerm™ human reconstructed epidermis model

(2009) Ting Hu et al.   TOXICOLOGY LETTERS