Transcriptional regulation of the mucosal immune system mediated by T-bet

T-bet and Eomesodermin Play Critical Roles in Directing T Cell Differentiation to Th1 versus Th17

(2014) Y. Yang et al.   JOURNAL OF IMMUNOLOGY

T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease

(2014) M. B. F. Werneck et al.   JOURNAL OF IMMUNOLOGY

Modular Utilization of Distal cis-Regulatory Elements Controls Ifng Gene Expression in T Cells Activated by Distinct Stimuli

(2010) Anand Balasubramani et al.   IMMUNITY

Characterization of IL-17A–Producing Cells in Celiac Disease Mucosa

(2010) Ivan Monteleone et al.   JOURNAL OF IMMUNOLOGY

IL-10 production by CD4+ effector T cells: a mechanism for self-regulation

(2010) D Jankovic et al.   Mucosal Immunology

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

(2010) Lena Öhman et al.   Nature Reviews Gastroenterology & Hepatology

Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin–Yang interplay between inflammation and cancer

(2010) S Danese et al.   ONCOGENE

Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa

(2009) M. M. Imanguli et al.   BLOOD

Colitis-Associated Colorectal Cancer Driven by T-bet Deficiency in Dendritic Cells

(2009) Wendy S. Garrett et al.   CANCER CELL

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

T-bet and pSTAT-1 expression in PBMC from coeliac disease patients: new markers of disease activity

(2009) G. Frisullo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neuroimmune mechanisms in postoperative ileus

(2009) G E Boeckxstaens et al.   GUT

Differential regulation of interleukin 17 and interferon   production in inflammatory bowel disease

(2009) L. Rovedatti et al.   GUT

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

T-bet-dependent regulation of CD8+T-cell expansion during experimentalTrypanosoma cruziinfection

(2009) Dustin Cobb et al.   IMMUNOLOGY

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

(2009) David Bending et al.   JOURNAL OF CLINICAL INVESTIGATION

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

(2009) Yuhong Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10–secreting Th1 cells

(2009) Leona Gabryšová et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Development of Airway Hyperreactivity in T-bet-Deficient Mice Requires CD1d-Restricted NKT Cells

(2009) H. Y. Kim et al.   JOURNAL OF IMMUNOLOGY

T-bet Knockout Prevents Helicobacter felis-Induced Gastric Cancer

(2009) C. Stoicov et al.   JOURNAL OF IMMUNOLOGY

Development of Allergen-Induced Airway Inflammation in the Absence of T-bet Regulation Is Dependent on IL-17

(2009) D. M. Durrant et al.   JOURNAL OF IMMUNOLOGY

T-bet-Deficient NOD Mice Are Protected from Diabetes Due to Defects in Both T Cell and Innate Immune System Function

(2009) J. H. Esensten et al.   JOURNAL OF IMMUNOLOGY

Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

(2009) A. Di Sabatino et al.   JOURNAL OF IMMUNOLOGY

Levels of Interferon-Gamma and Transcription Factor T-Bet in Progressive Periodontal Lesions in Patients With Chronic Periodontitis

(2009) Nicolas Dutzan et al.   JOURNAL OF PERIODONTOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

(2009) R. G. Jenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-γ Regulates Idiopathic Pneumonia Syndrome, a Th17+CD4+T-Cell–mediated Graft-versus-Host Disease

(2008) Nora Mauermann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Retraction: T-bet expression by dendritic cells is required for the repolarization of allergic airway inflammation

(2008) Karin L. Heckman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression

(2008) S. A. Miller et al.   GENES & DEVELOPMENT

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

(2008) T Kobayashi et al.   GUT

Blockade of transforming growth factor   upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa

(2008) A. Di Sabatino et al.   GUT

Restoration of T-box–containing protein expressed in T cells protects against allergen-induced asthma

(2008) Jung Won Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunophysiology of experimental food allergy

(2008) M C Berin et al.   Mucosal Immunology

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Anomalous Type 17 Response to Viral Infection by CD8+ T Cells Lacking T-bet and Eomesodermin

(2008) A. M. Intlekofer et al.   SCIENCE

Factors involved in the T helper type 1 and type 2 cell commitment and osteoclast regulation in inflammatory apical diseases

(2008) S. Y. Fukada et al.   Oral microbiology and immunology

Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease

(2007) D Fina et al.   GUT

T cell–specific T-box transcription factor haplotype is associated with allergic asthma in children

(2007) Monica Cheng Munthe-Kaas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY