标题
Prospects for neuroprotective therapies in prodromal Huntington's disease
作者
关键词
-
出版物
MOVEMENT DISORDERS
Volume 29, Issue 3, Pages 285-293
出版商
Wiley
发表日期
2014-02-27
DOI
10.1002/mds.25835
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport
- (2013) Diana Zala et al. CELL
- Role of oxidative DNA damage in mitochondrial dysfunction and Huntington’s disease pathogenesis
- (2013) Sylvette Ayala-Peña FREE RADICAL BIOLOGY AND MEDICINE
- PGC-1α, mitochondrial dysfunction, and Huntington's disease
- (2013) Ashu Johri et al. FREE RADICAL BIOLOGY AND MEDICINE
- Metabolic network as a progression biomarker of premanifest Huntington’s disease
- (2013) Chris C. Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Decreased Metabolism in the Cerebral Cortex in Early-Stage Huntington's Disease: A Possible Biomarker of Disease Progression?
- (2013) Hyeeun Shin et al. Journal of Clinical Neurology
- Cognitive decline in prodromal Huntington Disease: implications for clinical trials
- (2013) Jane S Paulsen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
- (2013) Sarah J Tabrizi et al. LANCET NEUROLOGY
- The impact of single-nucleotide polymorphisms (SNPs) in OGG1 and XPC on the age at onset of Huntington disease
- (2013) Frédérique Berger et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Glutathione peroxidase activity is neuroprotective in models of Huntington's disease
- (2013) Robert P Mason et al. NATURE GENETICS
- Huntington disease: How many repeats does it take?
- (2013) P. Hogarth NEUROLOGY
- Redefining the genetic risk for Huntington disease
- (2013) A. Feigin NEUROLOGY
- Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS
- (2013) A. Killoran et al. NEUROLOGY
- Structural MRI in Huntington's disease and recommendations for its potential use in clinical trials
- (2013) Nellie Georgiou-Karistianis et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset†
- (2012) Selma M. Soyal et al. HUMAN MOLECULAR GENETICS
- Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease
- (2012) A. Valencia et al. HUMAN MOLECULAR GENETICS
- Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression
- (2012) Andreas Weiss et al. JOURNAL OF CLINICAL INVESTIGATION
- R6/2 Huntington's Disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures
- (2012) E. Cepeda-Prado et al. JOURNAL OF NEUROSCIENCE
- Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington’s Disease
- (2012) Bruno M. D. C. Godinho et al. MOLECULAR PHARMACEUTICS
- Huntington's disease: How intermediate are intermediate repeat lengths?
- (2012) Ferdinando Squitieri et al. MOVEMENT DISORDERS
- Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
- (2012) Holly B. Kordasiewicz et al. NEURON
- Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ
- (2012) Youngnam N. Jin et al. PLoS One
- Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease
- (2012) Zhiyin Xun et al. Cell Reports
- Antioxidants in Huntington's disease
- (2011) Ashu Johri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
- (2011) Ashu Johri et al. HUMAN MOLECULAR GENETICS
- Energy deficit in Huntington disease: why it matters
- (2011) Fanny Mochel et al. JOURNAL OF CLINICAL INVESTIGATION
- Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
- (2011) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
- (2011) Mali Jiang et al. NATURE MEDICINE
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
- (2011) Hyunkyung Jeong et al. NATURE MEDICINE
- PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease
- (2011) Ming-Chang Chiang et al. NEUROBIOLOGY OF DISEASE
- Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease
- (2011) Sonia Franciosi et al. NEUROBIOLOGY OF DISEASE
- Truncated Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α Splice Variant Is Severely Altered in Huntington’s Disease
- (2011) Ashu Johri et al. Neurodegenerative Diseases
- Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
- (2011) Gisa Ellrichmann et al. PLoS One
- Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse
- (2011) Y. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Striatal and white matter predictors of estimated diagnosis for Huntington disease
- (2010) Jane S. Paulsen et al. BRAIN RESEARCH BULLETIN
- Seeking Brain Biomarkers for Preventive Therapy in Huntington Disease
- (2010) Mouna Esmaeilzadeh et al. CNS Neuroscience & Therapeutics
- Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease
- (2010) Cliona Stack et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
- (2010) J. Kim et al. HUMAN MOLECULAR GENETICS
- Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation
- (2010) R. K. Chaturvedi et al. HUMAN MOLECULAR GENETICS
- Longitudinal change in regional brain volumes in prodromal Huntington disease
- (2010) E. H. Aylward et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
- (2010) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects
- (2010) MOVEMENT DISORDERS
- Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease
- (2010) Tyisha Hathorn et al. NEUROBIOLOGY OF DISEASE
- Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis
- (2010) Juliette D. Godin et al. NEURON
- Self-paced timing detects and tracks change in prodromal Huntington disease.
- (2010) Kelly C. Rowe et al. NEUROPSYCHOLOGY
- Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity
- (2009) Lichuan Yang et al. ANTIOXIDANTS & REDOX SIGNALING
- Huntington's disease: Silencing a brutal killer
- (2009) Edith L. Pfister et al. EXPERIMENTAL NEUROLOGY
- Impaired PGC-1α function in muscle in Huntington's disease
- (2009) Rajnish K. Chaturvedi et al. HUMAN MOLECULAR GENETICS
- Obsessive and Compulsive Symptoms in Prediagnosed Huntington's Disease
- (2009) Leigh J. Beglinger et al. JOURNAL OF CLINICAL PSYCHIATRY
- The gene coding for PGC-1α modifies age at onset in Huntington's Disease
- (2009) Patrick Weydt et al. Molecular Neurodegeneration
- PGC-1alpha as modifier of onset age in Huntington disease
- (2009) Elahe Taherzadeh-Fard et al. Molecular Neurodegeneration
- Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice
- (2009) Ryan L Boudreau et al. MOLECULAR THERAPY
- Motor abnormalities in premanifest persons with Huntington's disease: The PREDICT-HD study
- (2009) Kevin M. Biglan et al. MOVEMENT DISORDERS
- Automatic detection of preclinical neurodegeneration: Presymptomatic Huntington disease
- (2009) S. Kloppel et al. NEUROLOGY
- Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription
- (2009) Lichuan Yang et al. PLoS One
- Huntingtin as an essential integrator of intracellular vesicular trafficking
- (2009) Juliane P. Caviston et al. TRENDS IN CELL BIOLOGY
- Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease
- (2008) Valerio Leoni et al. BRAIN
- Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
- (2008) Emilie Colin et al. EMBO JOURNAL
- A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
- (2008) Maria Björkqvist et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Detection of Huntington's disease decades before diagnosis: the Predict-HD study
- (2007) J S Paulsen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started