Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro

High Content Analysis technology for evaluating the joint toxicity of sunset yellow and sodium sulfite in vitro

(2017) Daofeng Qu et al.   FOOD CHEMISTRY

A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing

(2017) Fang Yu et al.   Scientific Reports

Judging the value of ‘liver-on-a-chip’ devices for prediction of toxicity

(2016) Viktoriia Starokozhko et al.   Expert Opinion on Drug Metabolism & Toxicology

An overview on adverse drug reactions to traditional Chinese medicines

(2015) Kelvin Chan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Review article: herbal hepatotoxicity - an update on traditional Chinese medicine preparations

(2014) R. Teschke et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Acute and sub-chronic toxicity profile of methanol leaf extract of Gouania longipetala in rats

(2014) Maxwell I. Ezeja et al.   JOURNAL OF ETHNOPHARMACOLOGY

Safety assessment of So-cheong-ryong-tang: Subchronic toxicity study in Crl:CD Sprague Dawley rats

(2014) MEE-YOUNG LEE et al.   Molecular Medicine Reports

Current approaches and future role of high content imaging in safety sciences and drug discovery

(2014) Erwin van Vliet   ALTEX-Alternatives to Animal Experimentation

Quinoline alkaloids and sesquiterpenes from the roots of Dictamnus angustifolius

(2013) Jian-Bo Sun et al.   BIOCHEMICAL SYSTEMATICS AND ECOLOGY

A simple and specific quantitative method for determination of dictamnine in Dictamni Cortex by 1H NMR spectroscopy

(2012) Pingping Zou et al.   Analytical Methods

Differential Mitochondrial Toxicity Screening and Multi-Parametric Data Analysis

(2012) Maria V. Tsiper et al.   PLoS One

Drug Safety Sciences and the Bottleneck in Drug Development

(2011) P B Watkins   CLINICAL PHARMACOLOGY & THERAPEUTICS

Central role of mitochondria in drug-induced liver injury

(2011) Dominique Pessayre et al.   DRUG METABOLISM REVIEWS

Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity

(2010) B.K. Park et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project

(2010) María José Gómez-Lechón et al.   TOXICOLOGY IN VITRO

An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells

(2009) Fozia Noor et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies

(2008) Gilles Labbe et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The current state of serum biomarkers of hepatotoxicity

(2007) Josef Ozer et al.   TOXICOLOGY