Drug Safety Sciences and the Bottleneck in Drug Development

Evaluation of Drug-Induced Serious Hepatotoxicity (eDISH)

(2011) Paul B. Watkins et al.   DRUG SAFETY

2010 FDA drug approvals

(2011) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development

(2009) Vaibhav Salvi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Monitoring for Hepatotoxicity: What Is the Predictive Value of Liver “Function” Tests?

(2009) JR Senior   CLINICAL PHARMACOLOGY & THERAPEUTICS

The future of drug safety testing: expanding the view and narrowing the focus

(2009) James L. Stevens et al.   DRUG DISCOVERY TODAY

Using controlled clinical trials to learn more about acute drug-induced liver injury

(2008) Paul B. Watkins et al.   HEPATOLOGY