Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?
出版年份 2014 全文链接
标题
Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?
作者
关键词
-
出版物
MOLECULES
Volume 19, Issue 11, Pages 17154-17172
出版商
MDPI AG
发表日期
2014-10-24
DOI
10.3390/molecules191117154
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A healthier approach to clinical trials evaluating resveratrol for primary prevention of age-related diseases in healthy populations
- (2016) James M. Smoliga et al. Aging-US
- Epigenetic aging: insights from network biology
- (2016) Andrew E. Teschendorff Aging-US
- Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function
- (2016) Kelly L. Stauch et al. Aging-US
- Aging and DNA damage in humans: a meta-analysis study
- (2016) Jorge Pinto Soares et al. Aging-US
- Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation
- (2014) Emma L. Wightman et al. BRITISH JOURNAL OF NUTRITION
- Prodrugs of Quercetin and Resveratrol: A Strategy Under Development
- (2014) Lucia Biasutto et al. CURRENT DRUG METABOLISM
- Resveratrol: review on therapeutic potential and recent advances in drug delivery
- (2014) Rudra Pangeni et al. Expert Opinion on Drug Delivery
- In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery
- (2014) S. Jose et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Recent advances of resveratrol in nanostructured based delivery systems and in the management of HIV/AIDS
- (2014) Gurinder Singh et al. JOURNAL OF CONTROLLED RELEASE
- Simultaneous quantification of trans-resveratrol and its sulfate and glucuronide metabolites in rat tissues by stable isotope-dilution UPLC–MS/MS analysis
- (2014) Bih-Show Lou et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men
- (2014) Jesper Olesen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Chemistry, Stability and Bioavailability of Resveratrol
- (2014) Antonio Franciosoa et al. Medicinal Chemistry
- Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus-systematic review and meta-analysis
- (2014) Heather A. Hausenblas et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK
- (2014) Anne Marie Thompson et al. PLoS One
- Development of a Lozenge for Oral Transmucosal Delivery of Trans-Resveratrol in Humans: Proof of Concept
- (2014) Otis L. Blanchard et al. PLoS One
- Inhibition of CYP17A1 activity by resveratrol, piceatannol, and synthetic resveratrol analogs
- (2014) Agneta Oskarsson et al. PROSTATE
- Pharmacokinetics
- (2013) Jianghong Fan et al. BIOCHEMICAL PHARMACOLOGY
- Optimization of trans-Resveratrol bioavailability for human therapy
- (2013) Marie Josephe Amiot et al. BIOCHIMIE
- Aging is not programmed
- (2013) Mikhail V Blagosklonny CELL CYCLE
- Influence of Glucuronidation and Reduction Modifications of Resveratrol on its Biological Activities
- (2013) Dong-Liang Lu et al. CHEMBIOCHEM
- Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults
- (2013) Rachel H.X. Wong et al. JOURNAL OF HYPERTENSION
- Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals
- (2013) Shu Wang et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Recent data do not provide evidence that resveratrol causes ‘mainly negative’ or ‘adverse’ effects on exercise training in humans
- (2013) James M. Smoliga et al. JOURNAL OF PHYSIOLOGY-LONDON
- Piperine potentiates the antidepressant-like effect of trans-resveratrol: involvement of monoaminergic system
- (2013) Wu Huang et al. METABOLIC BRAIN DISEASE
- Pharmacokinetics of pterostilbene in Sprague-Dawley rats: The impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability
- (2013) Samuel Chao Ming Yeo et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Pharmacokinetics, tissue distribution and excretion study of resveratrol and its prodrug 3,5,4′-tri-O-acetylresveratrol in rats
- (2013) Li Liang et al. PHYTOMEDICINE
- Resveratrol Metabolites Modify Adipokine Expression and Secretion in 3T3-L1 Pre-Adipocytes and Mature Adipocytes
- (2013) Itziar Eseberri et al. PLoS One
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence
- (2013) K. R. Patel et al. Science Translational Medicine
- The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters
- (2012) Joana M. Planas et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Resveratrol and piperine enhance radiosensitivity of tumor cells
- (2012) Jean-Kyoung Tak et al. BMB Reports
- A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma
- (2012) Rakesh Popat et al. BRITISH JOURNAL OF HAEMATOLOGY
- Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
- (2012) Sung-Jun Park et al. CELL
- SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
- (2012) Nathan L. Price et al. Cell Metabolism
- High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition
- (2012) M. M. Poulsen et al. DIABETES
- Resveratrol for primary prevention of atherosclerosis: Clinical trial evidence for improved gene expression in vascular endothelium
- (2012) Beamon Agarwal et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Distribution of Resveratrol Metabolites in Liver, Adipose Tissue, and Skeletal Muscle in Rats Fed Different Doses of This Polyphenol
- (2012) Cristina Andres-Lacueva et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Novel nanocomposite stent coating releasing resveratrol and quercetin reduces neointimal hyperplasia and promotes re-endothelialization
- (2012) James J. Kleinedler et al. JOURNAL OF CONTROLLED RELEASE
- Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats
- (2012) Shiuan-Pey Lin et al. JOURNAL OF ETHNOPHARMACOLOGY
- Arterial Pharmacokinetics of Red Wine Polyphenols: Implications for Novel Endovascular Therapies Targeting Restenosis
- (2012) James J. Kleinedler et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dose-dependent effect of Resveratrol on bladder cancer cells: Chemoprevention and oxidative stress
- (2012) Bianca Stocco et al. MATURITAS
- Delipidating effect of resveratrol metabolites in 3T3-L1 adipocytes
- (2012) Arrate Lasa et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Are sirtuins viable targets for improving healthspan and lifespan?
- (2012) Joseph A. Baur et al. NATURE REVIEWS DRUG DISCOVERY
- Resveratrol Exerts Dosage and Duration Dependent Effect on Human Mesenchymal Stem Cell Development
- (2012) Lindsay Peltz et al. PLoS One
- A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol
- (2012) Melanie Gertz et al. PLoS One
- Cyclodextrin-Based Nanosponges for Delivery of Resveratrol: In Vitro Characterisation, Stability, Cytotoxicity and Permeation Study
- (2011) Khalid A. Ansari et al. AAPS PHARMSCITECH
- Small-Molecule Allosteric Activators of Sirtuins
- (2011) David A. Sinclair et al. Annual Review of Pharmacology and Toxicology
- Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases--Safety, Pharmacokinetics, and Pharmacodynamics
- (2011) L. M. Howells et al. Cancer Prevention Research
- Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
- (2011) Silvie Timmers et al. Cell Metabolism
- Effect of food on the pharmacokinetic profile of trans-resveratrol
- (2011) M. Vaz-da-Silva et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Resveratrol Metabolites Do Not Elicit Early Pro-apoptotic Mechanisms in Neuroblastoma Cells
- (2011) Jason D. Kenealey et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Evaluation of the Stability and Antioxidant Activity of Nanoencapsulated Resveratrol during in Vitro Digestion
- (2011) Mariarenata Sessa et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Characterization of trans-Resveratrol-Loaded Lipid-Core Nanocapsules and Tissue Distribution Studies in Rats
- (2011) Rudimar L. Frozza et al. Journal of Biomedical Nanotechnology
- A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal
- (2011) Husam Ghanim et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Administration of resveratrol: What formulation solutions to bioavailability limitations?
- (2011) A. Amri et al. JOURNAL OF CONTROLLED RELEASE
- Resveratrol and health - A comprehensive review of human clinical trials
- (2011) James M. Smoliga et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Enhancing the bioavailability of resveratrol by combining it with piperine
- (2011) Jeremy J. Johnson et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Erroneous analyses of interactions in neuroscience: a problem of significance
- (2011) Sander Nieuwenhuis et al. NATURE NEUROSCIENCE
- Population Pharmacokinetic Modeling of trans-Resveratrol and Its Glucuronide and Sulfate Conjugates After Oral and Intravenous Administration in Rats
- (2011) Helena Colom et al. PHARMACEUTICAL RESEARCH
- The Use of 3,5,4′-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death
- (2011) Kazunori Koide et al. ACS Medicinal Chemistry Letters
- Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation
- (2010) David O Kennedy et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Pleiotropic mechanisms facilitated by resveratrol and its metabolites
- (2010) Barbara Calamini et al. BIOCHEMICAL JOURNAL
- Anticancer Activity and Molecular Mechanism of Resveratrol–Bovine Serum Albumin Nanoparticles on Subcutaneously Implanted Human Primary Ovarian Carcinoma Cells in Nude Mice
- (2010) Liyuan Guo et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis
- (2010) V. A. Brown et al. CANCER RESEARCH
- Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients
- (2010) K. R. Patel et al. CANCER RESEARCH
- Steady-State Pharmacokinetics and Tolerability of Trans-Resveratrol 2000 mg Twice Daily with Food, Quercetin and Alcohol (Ethanol) in Healthy Human Subjects
- (2010) Charles la Porte et al. CLINICAL PHARMACOKINETICS
- Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites
- (2010) Juma Hoshino et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic effects of resveratrol during acute periods following experimental ischemic stroke
- (2010) Jin A. Shin et al. JOURNAL OF NEUROIMMUNOLOGY
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Determination of Quercetin and Resveratrol in Whole Blood—Implications for Bioavailability Studies
- (2010) Lucia Biasutto et al. MOLECULES
- Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
- (2010) R.H.X. Wong et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
- (2009) Jesse J Smith et al. BMC Systems Biology
- Expression of sulfotransferases and sulfatases in human breast cancer: Impact on resveratrol metabolism
- (2009) Michaela Miksits et al. CANCER LETTERS
- Resveratrol/SRT-501
- (2009) P.J. Elliott et al. DRUGS OF THE FUTURE
- Pharmacokinetics ofTrans-resveratrol Following Repeated Administration in Healthy Elderly and Young Subjects
- (2009) Teresa Nunes et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Orotransmucosal drug delivery systems: A review
- (2009) N.V. Satheesh Madhav et al. JOURNAL OF CONTROLLED RELEASE
- Quantification of trans-resveratrol and its metabolites in rat plasma and tissues by HPLC
- (2009) M. Emília Juan et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers
- (2009) Luis Almeida et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor
- (2008) L. P. Volak et al. DRUG METABOLISM AND DISPOSITION
- The Impact of Aqueous Solubility and Dose on the Pharmacokinetic Profiles of Resveratrol
- (2008) Surajit Das et al. PHARMACEUTICAL RESEARCH
- Tissue distribution and excretion of resveratrol in rat after oral administration of Polygonum cuspidatum extract (PCE)
- (2008) Donggeng Wang et al. PHYTOMEDICINE
- The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats
- (2008) Alper Karaoglan et al. SURGICAL NEUROLOGY
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