Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs)
出版年份 2014 全文链接
标题
Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs)
作者
关键词
-
出版物
MOLECULES
Volume 20, Issue 1, Pages 249-292
出版商
MDPI AG
发表日期
2014-12-25
DOI
10.3390/molecules20010249
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer
- (2015) Ganji Purnachandra Nagaraju et al. CANCER LETTERS
- Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis
- (2015) Patrick R. Baldwin et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Antibacterial Activity of Synthetic Curcumin Derivatives: 3,5-Bis(benzylidene)-4-Piperidone (EF24) and EF24-Dimer Linked via Diethylenetriaminepentacetic Acid (EF2DTPA)
- (2014) Prachi Vilekar et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993)
- (2014) Joel M. Reid et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: involvement in osteoblastogenesis and osteoclastogenesis
- (2014) Masayoshi Yamaguchi et al. CELL AND TISSUE RESEARCH
- EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1
- (2014) Shala L. Thomas et al. CELL CYCLE
- Anti-HIV Small-Molecule Binding in the Peptide Subpocket of the CXCR4:CVX15 Crystal Structure
- (2014) Bryan D. Cox et al. CHEMBIOCHEM
- Synthetic Curcumin Analog UBS109 Inhibits the Growth of Head and Neck Squamous Cell Carcinoma Xenografts
- (2014) Shijun Zhu et al. CURRENT CANCER DRUG TARGETS
- Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents
- (2014) Nawras Samaan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Antioxidant Properties and PC12 Cell Protective Effects of a Novel Curcumin Analogue (2E,6E)-2,6-Bis(3,5- dimethoxybenzylidene)cyclohexanone (MCH)
- (2014) Gui-Zhen Ao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)2: A Novel Curcumin Analog
- (2014) Tao Zhou et al. PLoS One
- Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study
- (2014) Anuj Thakur et al. MedChemComm
- Liver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109
- (2014) Terry W. Moore et al. ACS Medicinal Chemistry Letters
- Recent developments in chemistry and biology of curcumin analogues
- (2014) Khemraj Bairwa et al. RSC Advances
- Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells
- (2013) Zhiguo Liu et al. BMC CANCER
- Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer
- (2013) Ganji Purnachandra Nagaraju et al. CANCER LETTERS
- Therapeutic role of EF24 targeting glucose transporter 1-mediated metabolism and metastasis in ovarian cancer cells
- (2013) Dandan Zhang et al. CANCER SCIENCE
- Synthesis and Evaluation of Curcumin-Related Compounds Containing Benzyl Piperidone for Their Effects on Human Cancer Cells
- (2013) Dai-Ying Zhou et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogs of curcumin as anti-inflammatory agents
- (2013) Zhiguo Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Novel STAT3 Small Molecule Inhibitors via in Silico Site-Directed Fragment-Based Drug Design
- (2013) Wenying Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Monocarbonyl Curcumin Analogues: Heterocyclic Pleiotropic Kinase Inhibitors That Mediate Anticancer Properties
- (2013) Andrew Brown et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo
- (2013) Chuan He Yang et al. PLoS One
- Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs
- (2013) Kellie S Rath et al. Journal of Ovarian Research
- Efflux Pumps of Mycobacterium tuberculosis Play a Significant Role in Antituberculosis Activity of Potential Drug Candidates
- (2012) Meenakshi Balganesh et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin
- (2012) Sunny Manohar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats
- (2012) Yong Pan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
- (2012) Jwa-Jin Kim et al. Cell Host & Microbe
- Curcumin Analogues with Potent and Selective Anti-proliferative Activity on Acute Promyelocytic Leukemia: Involvement of Accumulated Misfolded Nuclear Receptor Co-repressor (N-CoR) Protein as a Basis for Selective Activity
- (2012) Kheng-Lin Tan et al. ChemMedChem
- Fabrication of a Retinal-protein Photoreceptor Array
- (2012) Yingchun Zhao et al. CHINESE JOURNAL OF CHEMISTRY
- Synthesis and evaluation of curcumin-related compounds for anticancer activity
- (2012) Xingchuan Wei et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts
- (2012) Shijun Zhu et al. Integrative Biology
- Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition
- (2012) Masayoshi Yamaguchi et al. Integrative Biology
- EF24 suppresses maturation and inflammatory response in dendritic cells
- (2012) P. Vilekar et al. INTERNATIONAL IMMUNOLOGY
- RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER-negative breast cancer models
- (2012) BABASAHEB YADAV et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Attenuation of high-glucose-induced inflammatory response by a novel curcumin derivative B06 contributes to its protection from diabetic pathogenic changes in rat kidney and heart
- (2012) Yong Pan et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
- (2012) Iana M Serafimova et al. Nature Chemical Biology
- A Chemical Analog of Curcumin as an Improved Inhibitor of Amyloid Abeta Oligomerization
- (2012) Robert A. Orlando et al. PLoS One
- In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog
- (2012) Haitao Liu et al. PLoS One
- Low stability remedies the low bioavailability of curcumin
- (2012) Liang Shen et al. TRENDS IN MOLECULAR MEDICINE
- Vanillin and ferulic acid: not the major degradation products of curcumin
- (2012) Odaine N. Gordon et al. TRENDS IN MOLECULAR MEDICINE
- The pharmacology of curcumin: is it the degradation products?
- (2012) Liang Shen et al. TRENDS IN MOLECULAR MEDICINE
- (1E,4E)-1-(3-Nitrophenyl)-5-phenylpenta-1,4-dien-3-one
- (2011) S. Samshuddin et al. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
- (1E,4E)-1,5-Bis(2,6-difluorophenyl)penta-1,4-dien-3-one
- (2011) Jun-Da Huang et al. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
- The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines
- (2011) Stacey L Fossey et al. BMC CANCER
- Curcumin analog GO-Y030 is a novel inhibitor of IKKβ that suppresses NF-κB signaling and induces apoptosis
- (2011) Atsuko Sato et al. CANCER SCIENCE
- Curcumin analogues as possible anti-proliferative & anti-inflammatory agents
- (2011) A.-M. Katsori et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Multifaceted roles of curcumin: two sides of a coin!
- (2011) Sandhya A Marathe et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Microtubules as antifungal and antiparasitic drug targets
- (2011) Biswa Prasun Chatterji et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- A Novel Synthetic Mono-Carbonyl Analogue of Curcumin, A13, Exhibits Anti-Inflammatory Effects In vivo by Inhibition of Inflammatory Mediators
- (2011) Yi Wang et al. INFLAMMATION
- A synthetic compound, 1,5-bis(2-methoxyphenyl)penta- 1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells
- (2011) Jian Xiao et al. INTERNATIONAL JOURNAL OF CANCER
- A Novel Monocarbonyl Analogue of Curcumin, (1E,4E)-1,5-Bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, Induced Cancer Cell H460 Apoptosis via Activation of Endoplasmic Reticulum Stress Signaling Pathway
- (2011) Yi Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents
- (2011) Jianzhang Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of the pyridinyl analogues of dibenzylideneacetone (pyr-dba) via an improved Claisen–Schmidt condensation, displaying diverse biological activities as curcumin analogues
- (2011) Bin Cao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A Novel Compound C12 Inhibits Inflammatory Cytokine Production and Protects from Inflammatory Injury In Vivo
- (2011) Yi Wang et al. PLoS One
- Towards a Pharmacophore for Amyloid
- (2011) Meytal Landau et al. PLOS BIOLOGY
- Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo
- (2011) Chieko Kudo et al. BMC Pharmacology & Toxicology
- (3E,5E)-3,5-Bis(4-hydroxy-3,5-dimethoxybenzylidene)oxan-4-one monohydrate
- (2010) Zhi-Yun Du et al. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
- Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy
- (2010) Shala L. Thomas et al. BIOCHEMICAL PHARMACOLOGY
- Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease
- (2010) Daijiro Yanagisawa et al. BIOMATERIALS
- Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin
- (2010) Babasaheb Yadav et al. BIOORGANIC & MEDICINAL CHEMISTRY
- New antitumoral agents I: In vitro anticancer activity and in vivo acute toxicity of synthetic 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one and derivatives
- (2010) José Agustín Quincoces Suarez et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages
- (2010) Chengguang Zhao et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure–cytotoxicity relationship in a series of N-phosphorus substituted E,E-3,5-bis(3-pyridinylmethylene)- and E,E-3,5-bis(4-pyridinylmethylene)piperid-4-ones
- (2010) Evgeniya S. Leonova et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ – A structural insight to unveil antibacterial activity of curcumin
- (2010) Simranjeet Kaur et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Chrysophaentins A−H, Antibacterial Bisdiarylbutene Macrocycles That Inhibit the Bacterial Cell Division Protein FtsZ
- (2010) Alberto Plaza et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Perspectives on Chemopreventive and Therapeutic Potential of Curcumin Analogs in Medicinal Chemistry
- (2010) S. Padhye et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs
- (2009) Tushar K. Beuria et al. BIOCHEMICAL JOURNAL
- Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents
- (2009) Guang Liang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure–activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof
- (2009) Hiroyuki Yamakoshi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure–activity relationship studies of curcumin analogues
- (2009) James R. Fuchs et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo
- (2009) Hiroyuki Shibata et al. CANCER SCIENCE
- New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells
- (2009) Li Lin et al. CANCER SCIENCE
- Synthesis and structural determination of 3,5-bis(2-fluorobenzylidene)-4-piperidone analogs of curcumin
- (2009) Pallavi Lagisetty et al. JOURNAL OF MOLECULAR STRUCTURE
- Synthesis, crystal structure, and anticancer properties of cyclic monocarbonyl analogs of curcumin
- (2009) Natesan Sundarmurthy Karthikeyan et al. MEDICINAL CHEMISTRY RESEARCH
- Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity
- (2008) Dipti Rai et al. BIOCHEMICAL JOURNAL
- Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
- (2008) Preetha Anand et al. BIOCHEMICAL PHARMACOLOGY
- N-Aroyl-3,5-bis(benzylidene)-4-piperidones: A novel class of antimycobacterial agents
- (2008) Umashankar Das et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and exploration of novel curcumin analogues as anti-malarial agents
- (2008) Satyendra Mishra et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin
- (2008) Guang Liang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diphenyl Difluoroketone: A Curcumin Derivative with Potent In vivo Anticancer Activity
- (2008) D. Subramaniam et al. CANCER RESEARCH
- Synthesis and Anti-bacterial Properties of Mono-carbonyl Analogues of Curcumin
- (2008) Guang Liang et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues
- (2008) Guang Liang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Antioxidant, antimutagenic and antibacterial activities of curcumin-β-diglucoside
- (2008) K.S. Parvathy et al. FOOD CHEMISTRY
- Curcumin, a Known Phenolic from Curcuma longa, Attenuates the Virulence of Pseudomonas aeruginosa PAO1 in Whole Plant and Animal Pathogenicity Models
- (2008) Thimmaraju Rudrappa et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa
- (2008) Mamoru Shoji et al. JOURNAL OF DRUG TARGETING
- Inhibition of I B Kinase-Nuclear Factor- B Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin
- (2008) A. L. Kasinski et al. MOLECULAR PHARMACOLOGY
- Demethoxycurcumin and its Semisynthetic Analogues as Antitubercular Agents
- (2008) Dinesh Agrawal et al. PLANTA MEDICA
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