Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction in SH-SY5Y Cells via Inhibition of Mitochondrial Oxidation and Up-Regulation of DJ-1 Protein Expression

The Neurodegenerative Mitochondriopathies

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Myricitrin attenuates 6-hydroxydopamine-induced mitochondrial damage and apoptosis in PC12 cells via inhibition of mitochondrial oxidation

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Recent Updates in Redox Regulation and Free Radical Scavenging Effects by Herbal Products in Experimental Models of Parkinson’s Disease

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Cathepsin L is involved in 6-hydroxydopamine induced apoptosis of SH-SY5Y neuroblastoma cells

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Neuroprotective Effects of Vanillyl Alcohol in Gastrodia elata Blume Through Suppression of Oxidative Stress and Anti-Apoptotic Activity in Toxin-Induced Dopaminergic MN9D Cells

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Baicalein protects the brain against neuron impairments induced by MPTP in C57BL/6 mice

(2011) Xin Mu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Dangguijakyak-san, a medicinal herbal formula, protects dopaminergic neurons from 6-hydroxydopamine-induced neurotoxicity

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(2010) M. Flint Beal   NATURE

Oxidative Stress Induction of DJ-1 Protein in Reactive Astrocytes Scavenges Free Radicals and Reduces Cell Injury

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DJ-1 binds to mitochondrial complex I and maintains its activity

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Mitochondrial dysfunction in Parkinson's disease

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DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

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Ginsenoside Rg1 inhibits β-secretase activityin vitroand protects against Aβ-induced cytotoxicity in PC12 cells

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Protection Against Oxidative Stress-Induced Neurodegeneration by a Modulator for DJ-1, the Wild-Type of Familial Parkinson’s Disease-Linked PARK7

(2009) Takashi Yanagida et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro

(2009) Xin Mu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Inhibition of 6-hydroxydopamine-induced oxidative damage by 4,5-dihydro-3H-2-benzazepine N-oxides

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New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

(2008) Min Li-Weber   CANCER TREATMENT REVIEWS

6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells

(2008) Maria Gomez-Lazaro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective effect of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile

(2008) Yinxia Cheng et al.   NEUROSCIENCE LETTERS

Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection

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