The contribution of rare and common variants in 30 genes to risk nicotine dependence

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

(2013) Iuliana Ionita-Laza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Introduction to Deep Sequencing and Its Application to Drug Addiction Research with a Focus on Rare Variants

(2013) Shaolin Wang et al.   MOLECULAR NEUROBIOLOGY

Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations

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Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models

(2013) Sonia Marco et al.   NATURE MEDICINE

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

(2012) Seunggeun Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

(2012) Folkert W. Asselbergs et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis

(2012) Dorothée Diogo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Population-Specific Uncommon Variant in GRIN3A Associated with Schizophrenia

(2012) Atsushi Takata et al.   BIOLOGICAL PSYCHIATRY

Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry-A Meta-Analysis of Chromosome 15q25

(2012) Li-Shiun Chen et al.   GENETIC EPIDEMIOLOGY

New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer

(2012) Anna Chikova et al.   LIFE SCIENCES

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Rare Nonsynonymous Variants in Alpha-4 Nicotinic Acetylcholine Receptor Gene Protect Against Nicotine Dependence

(2011) Pingxing Xie et al.   BIOLOGICAL PSYCHIATRY

Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS

(2011) Gang Shi et al.   GENETIC EPIDEMIOLOGY

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

(2011) Gabe Haller et al.   HUMAN MOLECULAR GENETICS

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

(2011) Christie D. Fowler et al.   NATURE

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans

(2010) N. L. Saccone et al.   GENES BRAIN AND BEHAVIOR

Significant association of glutamate receptor, ionotropic N-methyl-d-aspartate 3A (GRIN3A), with nicotine dependence in European- and African-American smokers

(2010) Jennie Z. Ma et al.   HUMAN GENETICS

Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers

(2010) Jinxue Wei et al.   HUMAN GENETICS

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

(2010) Yingrui Li et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Resequencing of Nicotinic Acetylcholine Receptor Genes and Association of Common and Rare Variants with the Fagerström Test for Nicotine Dependence

(2010) Jennifer Wessel et al.   NEUROPSYCHOPHARMACOLOGY

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Genetic Variation in N-Methyl-D-Aspartate Receptor Subunit NR3A but Not NR3B Influences Susceptibility to Alzheimer’s Disease

(2009) Hsin-Ping Liu et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Detection of nonneutral substitution rates on mammalian phylogenies

(2009) K. S. Pollard et al.   GENOME RESEARCH

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

(2009) Bo Eskerod Madsen et al.   PLoS Genetics

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A functional polymorphism, rs6280, inDRD3is significantly associated with nicotine dependence in European-American smokers

(2008) Weihua Huang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers

(2008) J. Nussbaum et al.   HUMAN MOLECULAR GENETICS

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

Significant Association of ANKK1 and Detection of a Functional Polymorphism with Nicotine Dependence in an African-American Sample

(2008) Weihua Huang et al.   NEUROPSYCHOPHARMACOLOGY

Detection of Genetic Association and a Functional Polymorphism of Dynamin 1 Gene with Nicotine Dependence in European and African Americans

(2008) Qing Xu et al.   NEUROPSYCHOPHARMACOLOGY

Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function

(2007) A. Rigbi et al.   GENES BRAIN AND BEHAVIOR