Resequencing of Nicotinic Acetylcholine Receptor Genes and Association of Common and Rare Variants with the Fagerström Test for Nicotine Dependence

Interpretation of Association Signals and Identification of Causal Variants from Genome-wide Association Studies

(2010) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Behavioral Counseling and Varenicline Treatment for Smoking Cessation

(2010) Gary E. Swan et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Association of genes coding for the α-4, α-5, β-2 and β-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence

(2009) Jean-François Etter et al.   ADDICTIVE BEHAVIORS

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

(2009) Nancy L. Saccone et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence

(2009) Xiangning Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood

(2009) Kenneth A. Perkins et al.   BEHAVIOURAL PHARMACOLOGY

Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers

(2009) Kenneth A. Perkins et al.   BEHAVIOURAL PHARMACOLOGY

Clinical trial participant characteristics and saliva and DNA metrics

(2009) Denise M Nishita et al.   BMC Medical Research Methodology

Nicotinic Acetylcholine Receptor  2 Subunit (CHRNB2) Gene and Short-Term Ability to Quit Smoking in Response to Nicotine Patch

(2009) K. A. Perkins et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Nicotinic receptors and nicotine addiction

(2009) Jean-Pierre Changeux   COMPTES RENDUS BIOLOGIES

Common vs. rare allele hypotheses for complex diseases

(2009) Nicholas J Schork et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis

(2009) M. Sabatelli et al.   HUMAN MOLECULAR GENETICS

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

(2009) Rachel M. Freathy et al.   HUMAN MOLECULAR GENETICS

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

(2009) Kaisu Keskitalo et al.   HUMAN MOLECULAR GENETICS

Natural Variation within the Neuronal Nicotinic Acetylcholine Receptor Cluster on Human Chromosome 15q24: Influence on Heritable Autonomic Traits in Twin Pairs

(2009) B. K. Rana et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

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(2009) Tomas Drgon et al.   MOLECULAR MEDICINE

Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15

(2009) Y-Z Liu et al.   MOLECULAR PSYCHIATRY

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Dopamine Genes and Nicotine Dependence in Treatment-Seeking and Community Smokers

(2009) Andrew W Bergen et al.   NEUROPSYCHOPHARMACOLOGY

Common and Unique Biological Pathways Associated with Smoking Initiation/Progression, Nicotine Dependence and Smoking Cessation

(2009) Ju Wang et al.   NEUROPSYCHOPHARMACOLOGY

Examination of the Nicotine Dependence (NICSNP) Consortium findings in the Iowa adoption studies population

(2009) Robert A. Philibert et al.   NICOTINE & TOBACCO RESEARCH

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

(2009) Timothy B. Baker et al.   NICOTINE & TOBACCO RESEARCH

Association of nicotinic acetylcholine receptor subunit α4 polymorphisms with nicotine dependence in 5500 Germans

(2009) L P Breitling et al.   PHARMACOGENOMICS JOURNAL

Power of deep, all-exon resequencing for discovery of human trait genes

(2009) G. V. Kryukov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

(2009) Bo Eskerod Madsen et al.   PLoS Genetics

Evaluation of next generation sequencing platforms for population targeted sequencing studies

(2009) Olivier Harismendy et al.   GENOME BIOLOGY

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with ‘pleasurable buzz’ during early experimentation with smoking

(2008) Richard Sherva et al.   ADDICTION

A comparison of the Fagerström Test for Nicotine Dependence and smoking prevalence across countries

(2008) Karl Fagerström et al.   ADDICTION

A Combinatorial Approach to Detecting Gene-Gene and Gene-Environment Interactions in Family Studies

(2008) Xiang-Yang Lou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

High fractions of exogenous DNA in human buccal samples reduce the quality of large-scale genotyping

(2008) David López Herráez et al.   ANALYTICAL BIOCHEMISTRY

Gene-Gene Interactions Among CHRNA4, CHRNB2, BDNF, and NTRK2 in Nicotine Dependence

(2008) Ming D. Li et al.   BIOLOGICAL PSYCHIATRY

Smoking Cessation and Variations in Nicotinic Acetylcholine Receptor Subunits α-5, α-3, and β-4 Genes

(2008) Lutz Philipp Breitling et al.   BIOLOGICAL PSYCHIATRY

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Why Most Discovered True Associations Are Inflated

(2008) John P. A. Ioannidis   EPIDEMIOLOGY

Association of amyloid precursor protein-binding protein, family B, member 1 with nicotine dependence in African and European American smokers

(2008) Guo-Bo Chen et al.   HUMAN GENETICS

Nicotinic acetylcholine receptor β2 subunit gene implicated in a systems-based candidate gene study of smoking cessation

(2008) David V. Conti et al.   HUMAN MOLECULAR GENETICS

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

(2008) J C Wang et al.   MOLECULAR PSYCHIATRY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

Common and rare variants in multifactorial susceptibility to common diseases

(2008) Walter Bodmer et al.   NATURE GENETICS

Identification of genetic variants using bar-coded multiplexed sequencing

(2008) David W Craig et al.   NATURE METHODS

Genetic Association of the CHRNA6 and CHRNB3 Genes with Tobacco Dependence in a Nationally Representative Sample

(2008) Nicole R Hoft et al.   NEUROPSYCHOPHARMACOLOGY

A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction

(2008) Robert B. Weiss et al.   PLoS Genetics

Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction

(2007) Yann S. Mineur et al.   BIOCHEMICAL PHARMACOLOGY

Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function

(2007) A. Rigbi et al.   GENES BRAIN AND BEHAVIOR