A neurogenetics approach to understanding individual differences in brain, behavior and risk for psychopathology

Mineralocorticoid Receptor Iso/Val (rs5522) Genotype Moderates the Association Between Previous Childhood Emotional Neglect and Amygdala Reactivity

(2012) Ryan Bogdan et al.   AMERICAN JOURNAL OF PSYCHIATRY

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroscience, Clinical Evidence, and the Future of Psychiatric Classification in DSM-5

(2011) David J. Kupfer et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry

(2011) Laramie E. Duncan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide association studies of cerebral white matter lesion burden

(2011) Myriam Fornage et al.   ANNALS OF NEUROLOGY

Diffusion Imaging, White Matter, and Psychopathology

(2011) Moriah E. Thomason et al.   Annual Review of Clinical Psychology

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Deep Brain Stimulation for Psychiatric Disorders

(2011) Paul E. Holtzheimer et al.   Annual Review of Neuroscience

Association of Genetic Variants on 15q12 With Cortical Thickness and Cognition in Schizophrenia

(2011) Trygve E. Bakken   ARCHIVES OF GENERAL PSYCHIATRY

The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

(2011) Katja Karg et al.   ARCHIVES OF GENERAL PSYCHIATRY

Structural Neuroimaging Studies in Major Depressive Disorder

(2011) Matthew J. Kempton   ARCHIVES OF GENERAL PSYCHIATRY

The What, Where, and When of Catechol-O-Methyltransferase

(2011) Ahmad R. Hariri   BIOLOGICAL PSYCHIATRY

5-HTTLPR and COMTval158met genotype gate amygdala reactivity and habituation

(2011) Tina B. Lonsdorf et al.   BIOLOGICAL PSYCHOLOGY

Gene-environment interaction for childhood asthma and exposure to farming in Central Europe

(2011) Markus J. Ege et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Genetic Variation and Stress Interact to Influence Reward Learning

(2011) R. Bogdan et al.   JOURNAL OF NEUROSCIENCE

Stress-Related Methylation of the Catechol-O-Methyltransferase Val158 Allele Predicts Human Prefrontal Cognition and Activity

(2011) G. Ursini et al.   JOURNAL OF NEUROSCIENCE

Discovering imaging endophenotypes for major depression

(2011) G Hasler et al.   MOLECULAR PSYCHIATRY

Evidence of altered RNA stirs debate

(2011) Erika Check Hayden   NATURE

Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals

(2011) Young Seok Ju et al.   NATURE GENETICS

Multilocus Genetic Profile for Dopamine Signaling Predicts Ventral Striatum Reactivity

(2011) Yuliya S Nikolova et al.   NEUROPSYCHOPHARMACOLOGY

5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques

(2011) R. Bogdan et al.   NEUROSCIENCE LETTERS

Very Few RNA and DNA Sequence Differences in the Human Transcriptome

(2011) Daniel R. Schrider et al.   PLoS One

Serotonin transporter genotype modulates the association between depressive symptoms and amygdala activity among psychiatrically healthy adults

(2011) Seth J. Gillihan et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach

(2011) Fleur P. Velders et al.   PSYCHONEUROENDOCRINOLOGY

Reduced prefrontal functional connectivity in the default mode network is related to greater psychopathology in subjects with high genetic loading for schizophrenia

(2011) Joon Hwan Jang et al.   SCHIZOPHRENIA RESEARCH

Widespread RNA and DNA Sequence Differences in the Human Transcriptome

(2011) M. Li et al.   SCIENCE

Understanding risk for psychopathology through imaging gene–environment interactions

(2011) Luke W. Hyde et al.   TRENDS IN COGNITIVE SCIENCES

Differential susceptibility in youth: evidence that 5-HTTLPR x positive parenting is associated with positive affect ‘for better and worse’

(2011) B L Hankin et al.   Translational Psychiatry

Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability

(2010) Dina Ruano et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

(2010) Avshalom Caspi et al.   AMERICAN JOURNAL OF PSYCHIATRY

Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders

(2010) Thomas Insel et al.   AMERICAN JOURNAL OF PSYCHIATRY

Neurocognitive effects of HF-rTMS over the dorsolateral prefrontal cortex on the attentional processing of emotional information in healthy women: An event-related fMRI study

(2010) Rudi De Raedt et al.   BIOLOGICAL PSYCHOLOGY

Genome-wide association reveals genetic effects on human Aβ 42 and τ protein levels in cerebrospinal fluids: a case control study

(2010) Mi-Ryung Han et al.   BMC Neurology

A preliminary study of medial temporal lobe function in youths with a history of caregiver deprivation and emotional neglect

(2010) F. S. Maheu et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development

(2010) Tania L. Roth et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Endophenotype: a conceptual analysis

(2010) K S Kendler et al.   MOLECULAR PSYCHIATRY

Hints of hidden heritability in GWAS

(2010) Greg Gibson   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing

(2010) Hansoo Park et al.   NATURE GENETICS

Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: A review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry

(2010) Matthäus Willeit et al.   NEUROIMAGE

Imaging genetics—days of future past

(2010) Kristin L. Bigos et al.   NEUROIMAGE

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

(2010) Li Shen et al.   NEUROIMAGE

5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants

(2010) Jesse W. Richardson-Jones et al.   NEURON

Perceived social support moderates the link between threat-related amygdala reactivity and trait anxiety

(2010) Luke W. Hyde et al.   NEUROPSYCHOLOGIA

The serotonin transporter gene polymorphism and the effect of baseline on amygdala response to emotional faces

(2010) Elisabeth A.H. von dem Hagen et al.   NEUROPSYCHOLOGIA

Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response

(2010) Diego A Pizzagalli   NEUROPSYCHOPHARMACOLOGY

Genome-Wide Divergence of DNA Methylation Marks in Cerebral and Cerebellar Cortices

(2010) Yurong Xin et al.   PLoS One

Acute stress modulates genotype effects on amygdala processing in humans

(2010) H. Cousijn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association identifies candidate genes that influence the human electroencephalogram

(2010) C. A. Hodgkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopaminergic Network Differences in Human Impulsivity

(2010) J. W. Buckholtz et al.   SCIENCE

Overview of the Genetics of Major Depressive Disorder

(2010) Falk W. Lohoff   Current Psychiatry Reports

Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

(2010) Jean Mazella et al.   PLOS BIOLOGY

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

(2009)   AMERICAN JOURNAL OF PSYCHIATRY

The Neurobiology of Individual Differences in Complex Behavioral Traits

(2009) Ahmad R. Hariri   Annual Review of Neuroscience

Epigenetics and the Environmental Regulation of the Genome and Its Function

(2009) Tie-Yuan Zhang et al.   Annual Review of Psychology

Effects of HTR1A C(−1019)G on Amygdala Reactivity and Trait Anxiety

(2009) Eric Fakra et al.   ARCHIVES OF GENERAL PSYCHIATRY

Interaction of Childhood Maltreatment with the Corticotropin-Releasing Hormone Receptor Gene: Effects on Hypothalamic-Pituitary-Adrenal Axis Reactivity

(2009) Audrey R. Tyrka et al.   BIOLOGICAL PSYCHIATRY

Dissecting components of reward: ‘liking’, ‘wanting’, and learning

(2009) Kent C Berridge et al.   CURRENT OPINION IN PHARMACOLOGY

Effects of dopamine-related gene-gene interactions on working memory component processes

(2009) Christine Stelzel et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression

(2009) Neil Risch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Serotonin Transporter Availability in the Amygdala and Bed Nucleus of the Stria Terminalis Predicts Anxious Temperament and Brain Glucose Metabolic Activity

(2009) J. A. Oler et al.   JOURNAL OF NEUROSCIENCE

Vulnerability genes or plasticity genes?

(2009) J Belsky et al.   MOLECULAR PSYCHIATRY

Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis

(2009) D Mier et al.   MOLECULAR PSYCHIATRY

Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission

(2009) H P Jedema et al.   MOLECULAR PSYCHIATRY

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Assessing the neuroendocrine stress response in the functional neuroimaging context

(2009) Anthony P. King et al.   NEUROIMAGE

Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment

(2009) Ying-Jay Liou et al.   Pharmacogenetics and Genomics

Serotonin Transporter Genotype Modulates Social Reward and Punishment in Rhesus Macaques

(2009) Karli K. Watson et al.   PLoS One

Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease

(2009) Steven G. Potkin et al.   PLoS One

Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia

(2009) S. Whitfield-Gabrieli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

(2009) Elisabeth B. Binder   PSYCHONEUROENDOCRINOLOGY

Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone

(2009) Nienke van Leeuwen et al.   PSYCHONEUROENDOCRINOLOGY

Characterization of a glucocorticoid receptor gene (GR,NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance

(2008) Robert Kumsta et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Corticosteroid receptor-gene variants: Modulators of the stress-response and implications for mental health

(2008) Roel H. DeRijk et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Single dose of a dopamine agonist impairs reinforcement learning in humans: Evidence from event-related potentials and computational modeling of striatal-cortical function

(2008) Diane L. Santesso et al.   HUMAN BRAIN MAPPING

A Link between Serotonin-Related Gene Polymorphisms, Amygdala Activity, and Placebo-Induced Relief from Social Anxiety

(2008) T. Furmark et al.   JOURNAL OF NEUROSCIENCE

The serotonin transporter genotype is associated with intermediate brain phenotypes that depend on the context of eliciting stressor

(2008) N H Kalin et al.   MOLECULAR PSYCHIATRY

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Impact of interacting functional variants in COMT on regional gray matter volume in human brain

(2008) Robyn Honea et al.   NEUROIMAGE

Acute 5-HT Reuptake Blockade Potentiates Human Amygdala Reactivity

(2008) Kristin L Bigos et al.   NEUROPSYCHOPHARMACOLOGY

Pharmacogenetic Analysis of Genes Implicated in Rodent Models of Antidepressant Response: Association of TREK1 and Treatment Resistance in the STAR*D Study

(2008) Roy H Perlis et al.   NEUROPSYCHOPHARMACOLOGY

Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning

(2008) B. J. Kolber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of gene–environment interactions in depression: evidence that genes potentiate multiple sources of adversity

(2008) M. Wichers et al.   PSYCHOLOGICAL MEDICINE

A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype

(2008) Steven G. Potkin et al.   SCHIZOPHRENIA BULLETIN

Predicting Human Brain Activity Associated with the Meanings of Nouns

(2008) T. M. Mitchell et al.   SCIENCE

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics

Serotonin Transporter (5-HTTLPR) Genotype and Amygdala Activation: A Meta-Analysis

(2007) Marcus R. Munafò et al.   BIOLOGICAL PSYCHIATRY