HDAC and HAT Inhibitors Differently Affect Analgesia Mediated by Group II Metabotropic Glutamate Receptors

HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model

(2013) Yosuke Matsushita et al.   BRITISH JOURNAL OF PHARMACOLOGY

Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine

(2013) Bruna Cuccurazzu et al.   NEUROPSYCHOPHARMACOLOGY

Curcumin promotes nerve regeneration and functional recovery in rat model of nerve crush injury

(2013) Junxiong Ma et al.   NEUROSCIENCE LETTERS

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

(2013) Franziska Denk et al.   PAIN

SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition

(2013) Jesse E. Hanson et al.   PLoS One

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

(2013) C. Nasca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice

(2012) Carmelo Puglia et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

p300 Exerts an Epigenetic Role in Chronic Neuropathic Pain through its Acetyltransferase Activity in Rats following Chronic Constriction Injury (CCI)

(2012) Xiao-Yan Zhu et al.   Molecular Pain

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

(2012) Mitsumasa Kurita et al.   NATURE NEUROSCIENCE

Metabotropic glutamate receptors and the control of chronic pain

(2011) Santina Chiechio et al.   CURRENT OPINION IN PHARMACOLOGY

Curcumin Enhances the Efficacy of Chemotherapy by Tailoring p65NFκB-p300 Cross-talk in Favor of p53-p300 in Breast Cancer

(2011) Gouri Sankar Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mGlu2 Metabotropic Glutamate Receptors Restrain Inflammatory Pain and Mediate the Analgesic Activity of Dual mGlu2/mGlu3 Receptor Agonists

(2011) Magda Zammataro et al.   Molecular Pain

Epigenetic suppression of GAD65 expression mediates persistent pain

(2011) Zhi Zhang et al.   NATURE MEDICINE

Inhibition of Class II Histone Deacetylases in the Spinal Cord Attenuates Inflammatory Hyperalgesia

(2010) Guang Bai et al.   Molecular Pain

Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain

(2010) Santina Chiechio et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain

(2009) S. Chiechio et al.   MOLECULAR PHARMACOLOGY

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

(2008) Stephanie Spange et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity

(2008) Sebla B. Kutluay et al.   VIROLOGY