N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
出版年份 2014 全文链接
标题
N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
作者
关键词
-
出版物
Molecular Oncology
Volume 9, Issue 3, Pages 628-639
出版商
Wiley
发表日期
2014-11-17
DOI
10.1016/j.molonc.2014.10.014
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Effect of MDV3100, an androgen receptor signaling inhibitor (ARSI), on overall survival in patients with prostate cancer postdocetaxel: Results from the phase III AFFIRM study.
- (2017) Howard I. Scher et al. JOURNAL OF CLINICAL ONCOLOGY
- Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
- (2015) Bo Cao et al. Oncotarget
- Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
- (2014) Maria Thadani-Mulero et al. CANCER RESEARCH
- Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
- (2013) P. Vrignaud et al. CLINICAL CANCER RESEARCH
- Taxanes: Still a Major Weapon in the Armamentarium Against Prostate Cancer
- (2013) Yohann Loriot et al. EUROPEAN UROLOGY
- Taxane Mechanisms of Action: Potential Implications for Treatment Sequencing in Metastatic Castration-resistant Prostate Cancer
- (2013) John M. Fitzpatrick et al. EUROPEAN UROLOGY
- An androgen receptor N-terminal domain antagonist for treating prostate cancer
- (2013) Jae-Kyung Myung et al. JOURNAL OF CLINICAL INVESTIGATION
- New Paradigms in Microtubule-Mediated Endocrine Signaling in Prostate Cancer
- (2013) S. J. Mistry et al. MOLECULAR CANCER THERAPEUTICS
- A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
- (2013) Andrea Lunardi et al. NATURE GENETICS
- Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205
- (2012) Martin Puhr et al. AMERICAN JOURNAL OF PATHOLOGY
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
- (2012) Siu Chiu Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
- (2011) Y. Sun et al. CANCER RESEARCH
- Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer
- (2011) M. S. Darshan et al. CANCER RESEARCH
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Management of metastatic castration-resistant prostate cancer after first-line docetaxel
- (2011) J.A. Harrington et al. EUROPEAN JOURNAL OF CANCER
- Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
- (2011) Emma Hörnberg et al. PLoS One
- Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases
- (2011) Xiaotun Zhang et al. PLoS One
- A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
- (2011) Rong Hu et al. PROSTATE
- Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor
- (2010) Raymond J. Andersen et al. CANCER CELL
- Tubulin-Targeting Chemotherapy Impairs Androgen Receptor Activity in Prostate Cancer
- (2010) M.-L. Zhu et al. CANCER RESEARCH
- A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels
- (2010) Tamzin M. Tanner et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
- (2010) Karin Jennbacken et al. ENDOCRINE-RELATED CANCER
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
- (2010) Hiroshi Tanaka et al. NATURE MEDICINE
- Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer
- (2010) Karen E. Knudsen et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- EMT, the cytoskeleton, and cancer cell invasion
- (2009) Mahmut Yilmaz et al. CANCER AND METASTASIS REVIEWS
- Dysfunctional Transforming Growth Factor- Receptor II Accelerates Prostate Tumorigenesis in the TRAMP Mouse Model
- (2009) H. Pu et al. CANCER RESEARCH
- Inhibition of the Androgen Receptor as a Novel Mechanism of Taxol Chemotherapy in Prostate Cancer
- (2009) L. Gan et al. CANCER RESEARCH
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells
- (2009) Meng-Lei Zhu et al. FASEB JOURNAL
- Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line
- (2009) Gemma Marcias et al. HUMAN MUTATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
- Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
- (2008) Jing Yang et al. DEVELOPMENTAL CELL
- Transcriptional regulation of cell polarity in EMT and cancer
- (2008) G Moreno-Bueno et al. ONCOGENE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now