The Glutathione System: A New Drug Target in Neuroimmune Disorders

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

(2013) Gerwyn Morris et al.   BMC Medicine

A randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders

(2013) Ahmad Ghanizadeh et al.   BMC Psychiatry

N-Acetylcysteine as an Adjunct to Risperidone for Treatment of Negative Symptoms in Patients With Chronic Schizophrenia

(2013) Mehdi Farokhnia et al.   CLINICAL NEUROPHARMACOLOGY

Dimethyl Fumarate for Treatment of Multiple Sclerosis: Mechanism of Action, Effectiveness, and Side Effects

(2013) Ralf A. Linker et al.   Current Neurology and Neuroscience Reports

Interplay between the pro-oxidant and antioxidant systems and proinflammatory cytokine levels, in relation to iron metabolism and the erythron in depression

(2013) Joanna Rybka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modulation of glutathione intracellular levels alters the spontaneous proliferation of lymphocyte from HTLV-1 infected patients

(2013) Renata Novaes et al.   IMMUNOBIOLOGY

Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways

(2013) Gerwyn Morris et al.   METABOLIC BRAIN DISEASE

Glutathione: A redox signature in monitoring EPI-743 therapy in children with mitochondrial encephalomyopathies

(2013) Anna Pastore et al.   MOLECULAR GENETICS AND METABOLISM

Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats

(2013) Sawsan Aboul-Fotouh   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Inhibitory Effect of Glutathione on Oxidative Liver Injury Induced by Dengue Virus Serotype 2 Infections in Mice

(2013) Juan Wang et al.   PLoS One

Antifatigue Effects of Panax ginseng C.A. Meyer: A Randomised, Double-Blind, Placebo-Controlled Trial

(2013) Hyeong-Geug Kim et al.   PLoS One

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells

(2013) Megan L. Steele et al.   Redox Biology

l-Methylfolate as Adjunctive Therapy for SSRI-Resistant Major Depression: Results of Two Randomized, Double-Blind, Parallel-Sequential Trials

(2012) George I. Papakostas et al.   AMERICAN JOURNAL OF PSYCHIATRY

Protein-Thiol Oxidation and Cell Death: Regulatory Role of Glutaredoxins

(2012) Erin M.G. Allen et al.   ANTIOXIDANTS & REDOX SIGNALING

Nuclear glutathione

(2012) José Luis García-Giménez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inflammation, DNA methylation and colitis-associated cancer

(2012) L. Hartnett et al.   CARCINOGENESIS

Mitochondrial Ca2+ and apoptosis

(2012) Carlotta Giorgi et al.   CELL CALCIUM

Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells

(2012) Jaleel Kizhakkayil et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein thiyl radical mediates S-glutathionylation of complex I

(2012) Patrick T. Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes

(2012) Mazen Kurdi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The relevance of oxidative stress status in first episode and recurrent depression

(2012) Cristinel Stefanescu et al.   JOURNAL OF AFFECTIVE DISORDERS

Indirect Moxibustion (CV4 and CV8) Ameliorates Chronic Fatigue: A Randomized, Double-Blind, Controlled Study

(2012) Hyeong Geug Kim et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

N-acetylcysteine reverses cardiac myocyte dysfunction in HIV-Tat proteinopathy

(2012) Fangping Chen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Glutathione/thioredoxin systems modulate mitochondrial H2O2emission: An experimental-computational study

(2012) Miguel Antonio Aon et al.   JOURNAL OF GENERAL PHYSIOLOGY

Coenzyme Q10 Effects on Creatine Kinase Activity and Mood in Geriatric Bipolar Depression

(2012) Brent P. Forester et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation

(2012) Junpei Takaki et al.   Journal of Neuroinflammation

Oxidative stress and glutathione response in tissue cultures from persons with major depression

(2012) Sara A. Gibson et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Increased nuclear factor-κB and loss of p53 are key mechanisms in Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS)

(2012) Gerwyn Morris et al.   MEDICAL HYPOTHESES

A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome

(2012) Gerwyn Morris et al.   METABOLIC BRAIN DISEASE

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications

(2012) S Moylan et al.   MOLECULAR PSYCHIATRY

Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology

(2012) Dikoma C. Shungu et al.   NMR IN BIOMEDICINE

Lipoic Acid Improves Mitochondrial Function in Nonalcoholic Steatosis Through the Stimulation of Sirtuin 1 and Sirtuin 3

(2012) M. Pilar Valdecantos et al.   Obesity

Putative neuroprotective agents in neuropsychiatric disorders

(2012) Seetal Dodd et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Association between three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to bipolar disorder

(2012) Zahra Rezaei et al.   PSYCHIATRY RESEARCH

Plasma thiol status is altered in children with mitochondrial diseases

(2012) Heli Salmi et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes

(2012) Sung Gu Han et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases

(2012) William M. Johnson et al.   Nutrients

Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile

(2012) Rima Kaddurah-Daouk et al.   Scientific Reports

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

(2012) Jillian C Belrose et al.   Molecular Brain

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

(2012) S Rose et al.   Translational Psychiatry

New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates—Nrf2 activators and GSK-3 inhibitors

(2012) Michael Maes et al.   INFLAMMOPHARMACOLOGY

Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization

(2011) Y. Kamide et al.   ALLERGY

Epigenetic Mechanisms of Depression and Antidepressant Action

(2011) Vincent Vialou et al.   Annual Review of Pharmacology and Toxicology

Resveratrol Improves Hippocampal Atrophy in Chronic Fatigue Mice by Enhancing Neurogenesis and Inhibiting Apoptosis of Granular Cells

(2011) Junji Moriya et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The effects of hyperbaric oxygen therapy on blood–brain barrier permeability in septic rats

(2011) Sezen Milli Avtan et al.   BRAIN RESEARCH

A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: Modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium

(2011) John J. Haddad   CELLULAR IMMUNOLOGY

Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control

(2011) Chitranshu Kumar et al.   EMBO JOURNAL

Prefrontal cortex glutathione S-transferase levels in patients with bipolar disorder, major depression and schizophrenia

(2011) Jeremy W. Gawryluk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Glutamate cysteine ligase (GCL) and self reported depression: An association study from the HUNT

(2011) Michael Berk et al.   JOURNAL OF AFFECTIVE DISORDERS

The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: An open label trial

(2011) Michael Berk et al.   JOURNAL OF AFFECTIVE DISORDERS

Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway

(2011) Ildefonso Rodríguez-Ramiro et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells

(2011) Lili Ji et al.   MOLECULAR CARCINOGENESIS

Genistein attenuates genioglossus muscle fatigue under chronic intermittent hypoxia by down-regulation of oxidative stress level and up-regulation of antioxidant enzyme activity through ERK1/2 signaling pathway

(2011) WH Ding et al.   ORAL DISEASES

Aged Red Garlic Extract Reduces Cigarette Smoke Extract-induced Cell Death in Human Bronchial Smooth Muscle Cells by Increasing Intracellular Glutathione Levels

(2011) Yi-Yeong Jeong et al.   PHYTOTHERAPY RESEARCH

Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult

(2011) Julie M. Robillard et al.   PLoS One

N-acetylcysteine for major depressive episodes in bipolar disorder

(2011) Pedro V Magalhães et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Potentials of Curcumin as an Antidepressant

(2011) S.K. Kulkarni et al.   TheScientificWorldJOURNAL

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Glutathione Peroxidase 1 Deficiency Attenuates Allergen-Induced Airway Inflammation by Suppressing Th2 and Th17 Cell Development

(2010) Hee Yeon Won et al.   ANTIOXIDANTS & REDOX SIGNALING

Differential Dependence on Cysteine from Transsulfuration versus Transport During T Cell Activation

(2010) Sanjay K. Garg et al.   ANTIOXIDANTS & REDOX SIGNALING

Environmentally induced oxidative stress in aquatic animals

(2010) Volodymyr I. Lushchak   AQUATIC TOXICOLOGY

Metabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes

(2010) Werner Siems et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Inhibitory effects of glutathione on dengue virus production

(2010) Yanping Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thioredoxin and thioredoxin reductase: Current research with special reference to human disease

(2010) Arne Holmgren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A nuclear glutathione cycle within the cell cycle

(2010) Pedro Diaz Vivancos et al.   BIOCHEMICAL JOURNAL

Redox Remodeling as an Immunoregulatory Strategy

(2010) Zhonghua Yan et al.   BIOCHEMISTRY

Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium

(2010) Freya L. Sheeran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Redox-optimized ROS balance: A unifying hypothesis

(2010) M.A. Aon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Adaptive response to oxidative stress: Bacteria, fungi, plants and animals

(2010) Volodymyr I. Lushchak   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

The use of thiols by ribonucleotide reductase

(2010) Arne Holmgren et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of glutathione in cell nucleus

(2010) Jelena Markovic et al.   FREE RADICAL RESEARCH

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

(2010) Jeremy W. Gawryluk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Respiration-dependent H2O2Removal in Brain Mitochondria via the Thioredoxin/Peroxiredoxin System

(2010) Derek A. Drechsel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione Synthesis and Turnover in the Human Erythrocyte

(2010) Julia E. Raftos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory T Cells Interfere with Glutathione Metabolism in Dendritic Cells and T Cells

(2010) Zhonghua Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c

(2010) Takeshi Kanno et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transcriptional Upregulation of Nrf2-Dependent Phase II Detoxification Genes in the Involved Epidermis of Vitiligo Vulgaris

(2010) Vivek T. Natarajan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Intracellular GSH Depletion Triggered Mitochondrial Bax Translocation to Accomplish Resveratrol-Induced Apoptosis in the U937 Cell Line

(2010) P. Guha et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genetic polymorphisms of glutathione S-transferase Z1 in an Iranian population

(2010) Samane Nafissi et al.   MOLECULAR BIOLOGY REPORTS

Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans

(2010) Dean P. Jones et al.   NUTRITION

Markers of Oxidative Stress in Erythrocytes and Plasma During Aging in Humans

(2010) Kanti Bhooshan Pandey et al.   Oxidative Medicine and Cellular Longevity

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

(2010) Marta Kubera et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Genetic polymorphisms of glutathione S-transferases GSTM1, GSTT1, GSTP1 and GSTA1 as risk factors for schizophrenia

(2010) Paolo Gravina et al.   PSYCHIATRY RESEARCH

Green tea consumption is associated with depressive symptoms in the elderly

(2009) Kaijun Niu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Redox Regulation of γ-Glutamyl Transpeptidase

(2009) Hongqiao Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nitric Oxide in Cell Survival: A Janus Molecule

(2009) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and biochemical evidence

(2009) Anand Kamal Sachdeva et al.   BEHAVIOURAL BRAIN RESEARCH

Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism

(2009) Toshiyuki Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

(2009) Andrew G. Cox et al.   BIOCHEMICAL JOURNAL

Functions of coenzyme Q10in inflammation and gene expression

(2009) Constance Schmelzer et al.   BIOFACTORS

Apoptosis and glutathione: beyond an antioxidant

(2009) R Franco et al.   CELL DEATH AND DIFFERENTIATION

Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells

(2009) Cassandra A. Godman et al.   CELL STRESS & CHAPERONES

Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal†

(2009) Xiaochun Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

(2009) Nina Kaludercic et al.   CIRCULATION RESEARCH

Fumaric Acid and its Esters: An Emerging Treatment for Multiple Sclerosis

(2009) D. Moharregh-Khiabani et al.   Current Neuropharmacology

Protective effects of antidepressants against chronic fatigue syndrome - induced behavioral changes and biochemical alterations

(2009) Anil Kumar et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Molecular Mechanisms of Thioredoxin and Glutaredoxin as Hydrogen Donors for Mammalian S Phase Ribonucleotide Reductase

(2009) Farnaz Zahedi Avval et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantification of hydroxyl radical produced during phacoemulsification

(2009) Jonathan M. Gardner et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

Role of nuclear glutathione as a key regulator of cell proliferation

(2009) Federico V. Pallardó et al.   MOLECULAR ASPECTS OF MEDICINE

Extracellular redox modulation by regulatory T cells

(2009) Zhonghua Yan et al.   Nature Chemical Biology

The Depletion of Nuclear Glutathione Impairs Cell Proliferation in 3t3 Fibroblasts

(2009) Jelena Markovic et al.   PLoS One

Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia

(2009) K. R. Atkuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An in vivo proton neurospectroscopy study of cerebral oxidative stress in myalgic encephalomyelitis (chronic fatigue syndrome)

(2009) B.K. Puri et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Mechanisms and Clinical Implications of Reversible Protein S-Glutathionylation

(2008) John J. Mieyal et al.   ANTIOXIDANTS & REDOX SIGNALING

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Redox compartmentalization in eukaryotic cells

(2008) Young-Mi Go et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial

(2008) Michael Berk et al.   BIOLOGICAL PSYCHIATRY

Glutathione and Parkinson's disease: Is this the elephant in the room?

(2008) Gail D. Zeevalk et al.   BIOMEDICINE & PHARMACOTHERAPY

Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[ a ]pyrene-treated mice: mechanism of its anti-initiating action

(2008) Rachana Garg et al.   CARCINOGENESIS

Kinetic Analysis of Intracellular Concentrations of Reactive Nitrogen Species

(2008) Chang Hoon Lim et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

(2008) Georg T. Wondrak et al.   FREE RADICAL BIOLOGY AND MEDICINE

The glutathione precursor N-acetylcysteine improves immune function in postmenopausal women

(2008) L ARRANZ et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

(2008) C.J. Harvey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glutathione and apoptosis

(2008) Magdalena L. Circu et al.   FREE RADICAL RESEARCH

Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia

(2008) F. Auchere et al.   HUMAN MOLECULAR GENETICS

Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model

(2008) Amit Gupta et al.   IMMUNOBIOLOGY

Serum homocysteine levels and cognitive functioning in euthymic bipolar patients

(2008) Vasco Videira Dias et al.   JOURNAL OF AFFECTIVE DISORDERS

Oxidative stress is fundamental to hyperbaric oxygen therapy

(2008) Stephen R. Thom   JOURNAL OF APPLIED PHYSIOLOGY

Novel Role for GlutathioneS-Transferase π

(2008) Danyelle M. Townsend et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Redox Environment in the Mitochondrial Intermembrane Space Is Maintained Separately from the Cytosol and Matrix

(2008) Jingjing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Neuronal Glutathione Synthesis

(2008) Koji Aoyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c

(2008) Allyson E. Vaughn et al.   NATURE CELL BIOLOGY

Venlafaxine reverses chronic fatigue-induced behavioral, biochemical and neurochemical alterations in mice

(2008) Ashish Dhir et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T 1H-MRS Study

(2008) Daisuke Matsuzawa et al.   PLoS One

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

(2007) Aruna Kode et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibition of murine AIDS by pro-glutathione (GSH) molecules

(2007) A. Fraternale et al.   ANTIVIRAL RESEARCH

How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis

(2007) Richard Deth et al.   NEUROTOXICOLOGY