The Role of Clusterin in Alzheimer’s Disease: Pathways, Pathogenesis, and Therapy

Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease

(2017) Yitshak I. Francis et al.   JOURNAL OF ALZHEIMERS DISEASE

Proteome-Based Plasma Markers of Brain Amyloid-β Deposition in Non-Demented Older Individuals

(2017) Madhav Thambisetty et al.   JOURNAL OF ALZHEIMERS DISEASE

The Role of Clusterin, Complement Receptor 1, and Phosphatidylinositol Binding Clathrin Assembly Protein in Alzheimer Disease Risk and Cerebrospinal Fluid Biomarker Levels

(2011) Brit-Maren M. Schjeide et al.   ARCHIVES OF GENERAL PSYCHIATRY

Neural hyperactivation in carriers of the Alzheimer's risk variant on the clusterin gene

(2011) Thomas M. Lancaster et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Common Alzheimer's Disease Risk Variant Within the CLU Gene Affects White Matter Microstructure in Young Adults

(2011) M. N. Braskie et al.   JOURNAL OF NEUROSCIENCE

Serum Clusterin Levels Are Not Increased in Presymptomatic Alzheimer’s Disease

(2011) Linda IJsselstijn et al.   JOURNAL OF PROTEOME RESEARCH

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment

(2011) Madhav Thambisetty et al.   NEUROIMAGE

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

Alzheimer's risk variants in the clusterin gene are associated with alternative splicing

(2011) M Szymanski et al.   Translational Psychiatry

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease

(2010) Minerva M. Carrasquillo et al.   ARCHIVES OF NEUROLOGY

Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes

(2010) Gyungah Jun   ARCHIVES OF NEUROLOGY

Identification of Novel Loci for Alzheimer Disease and Replication of CLU, PICALM, and BIN1 in Caribbean Hispanic Individuals

(2010) Joseph H. Lee et al.   ARCHIVES OF NEUROLOGY

Implication of CLU gene polymorphisms in Chinese patients with Alzheimer's disease

(2010) Jin-Tai Yu et al.   CLINICA CHIMICA ACTA

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

(2010) Jason J. Corneveaux et al.   HUMAN MOLECULAR GENETICS

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old

(2010) Jonas Mengel-From et al.   NEUROBIOLOGY OF AGING

Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

(2010) Tapio Nuutinen et al.   NEUROSCIENCE LETTERS

Genetic Variability in CLU and Its Association with Alzheimer's Disease

(2010) Rita J. Guerreiro et al.   PLoS One

Epigenetic regulation in the pathophysiology of Alzheimer's disease

(2010) Leonidas Chouliaras et al.   PROGRESS IN NEUROBIOLOGY

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects

(2010) Kristel Sleegers et al.   TRENDS IN GENETICS

The role of epigenetics in aging and age-related diseases

(2009) Vincenzo Calvanese et al.   AGEING RESEARCH REVIEWS

Clusterin: A forgotten player in Alzheimer's disease

(2009) Tapio Nuutinen et al.   BRAIN RESEARCH REVIEWS

Identification of Clusterin Domain Involved in NF-κB Pathway Regulation

(2009) Abdellatif Essabbani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase inhibitors: Potential in cancer therapy

(2009) P.A. Marks et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

(2009) Nicholas H. Varvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholesterol metabolism and transport in the pathogenesis of Alzheimer’s disease

(2009) Ian J. Martins et al.   JOURNAL OF NEUROCHEMISTRY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Meta-analysis of linkage studies for Alzheimer's disease—A web resource

(2009) Amy W. Butler et al.   NEUROBIOLOGY OF AGING

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Clusterin is epigenetically regulated in prostate cancer

(2008) Hanna E. Rauhala et al.   INTERNATIONAL JOURNAL OF CANCER

Structural and Quantitative Comparison of Cerebrospinal Fluid Glycoproteins in Alzheimer’s Disease Patients and Healthy Individuals

(2008) Carina Sihlbom et al.   NEUROCHEMICAL RESEARCH

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

(2008) Sun-Chong Wang et al.   PLoS One

Clusterin, a novel modulator of TGF-β signaling, is involved in Smad2/3 stability

(2007) Kwan-Bok Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of NF-κB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis

(2007) O. Takase et al.   KIDNEY INTERNATIONAL