Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage Response

(2014) A. M. Abdallah et al.   JOURNAL OF IMMUNOLOGY

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish

(2012) Eveline M. Weerdenburg et al.   CELLULAR MICROBIOLOGY

Comparative Genomics ofesxGenes from Clinical Isolates of Mycobacterium tuberculosis Provides Evidence for Gene Conversion and Epitope Variation

(2011) Swapna Uplekar et al.   INFECTION AND IMMUNITY

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway

(2011) Maria H. Daleke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis

(2011) Daria Bottai et al.   JOURNAL OF INFECTIOUS DISEASES

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Screening of Predicted Secreted Antigens from Mycobacterium bovis Reveals the Immunodominance of the ESAT-6 Protein Family

(2010) G. J. Jones et al.   INFECTION AND IMMUNITY

The Multifunctional PE_PGRS11 Protein fromMycobacterium tuberculosisPlays a Role in Regulating Resistance to Oxidative Stress

(2010) Rashmi Chaturvedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

(2010) Priscille Brodin et al.   PLoS Pathogens

EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity

(2010) Alejandra Garces et al.   PLoS Pathogens

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants

(2009) Stephen V. Gordon et al.   BIOESSAYS

ESX/type VII secretion systems and their role in host–pathogen interaction

(2009) Roxane Simeone et al.   CURRENT OPINION IN MICROBIOLOGY

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

(2009) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

(2009) Abdallah M. Abdallah et al.   MOLECULAR MICROBIOLOGY

Systematic Genetic Nomenclature for Type VII Secretion Systems

(2009) Wilbert Bitter et al.   PLoS Pathogens

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

(2008) T. P. Stinear et al.   GENOME RESEARCH

Frequent Homologous Recombination Events in Mycobacterium tuberculosis PE/PPE Multigene Families: Potential Role in Antigenic Variability

(2008) A. Karboul et al.   JOURNAL OF BACTERIOLOGY

Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP

(2008) Wafa Frigui et al.   PLoS Pathogens

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of outer membrane proteins of Mycobacterium tuberculosis

(2008) Houhui Song et al.   TUBERCULOSIS