Structure, regulation and cellular functions of Rab geranylgeranyl transferase and its cellular partner Rab Escort Protein

CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the retinal pigment epithelium of choroideremia mice

(2012) Tanya Tolmachova et al.   JOURNAL OF GENE MEDICINE

Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with rab geranylgeranyl transferase

(2011) Gabriella Esposito et al.   HUMAN MUTATION

Regulation of β2-Adrenergic Receptor Maturation and Anterograde Trafficking by an Interaction with Rab Geranylgeranyltransferase

(2011) Véronik Lachance et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Biochemical and molecular mechanisms of action of bisphosphonates

(2010) Michael J. Rogers et al.   BONE

Understanding and Exploiting Protein Prenyltransferases

(2010) Uyen T. T. Nguyen et al.   CHEMBIOCHEM

Arabidopsis RAB geranylgeranyl transferase β-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects

(2010) Michal Hála et al.   PLANT JOURNAL

Rab GTPases implicated in inherited and acquired disorders

(2010) Shreya Mitra et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis

(2009) J. Singh et al.   GENES & DEVELOPMENT

Spp382p Interacts with Multiple Yeast Splicing Factors, Including Possible Regulators of Prp43 DExD/H-Box Protein Function

(2009) S. Pandit et al.   GENETICS

Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation

(2009) Yao-Wen Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sfp1 Interaction with TORC1 and Mrs6 Reveals Feedback Regulation on TOR Signaling

(2009) Harri Lempiäinen et al.   MOLECULAR CELL

The functional effect of pathogenic mutations in Rab escort protein 1

(2009) Y.V. Sergeev et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging

(2009) Uyen T T Nguyen et al.   Nature Chemical Biology

Griscelli syndrome: a model system to study vesicular trafficking

(2009) Mireille Van Gele et al.   Pigment Cell & Melanoma Research

The Plastidial 2-C-Methyl-D-Erythritol 4-Phosphate Pathway Provides the Isoprenyl Moiety for Protein Geranylgeranylation in Tobacco BY-2 Cells

(2009) E. Gerber et al.   PLANT CELL

Loss-of-Function Mutations in Rab Escort Protein 1 (REP-1) Affect Intracellular Transport in Fibroblasts and Monocytes of Choroideremia Patients

(2009) Natalia V. Strunnikova et al.   PLoS One

Geranylgeranyl transferase type II inhibition prevents myeloma bone disease

(2008) Michelle A. Lawson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation

(2008) Zhong Guo et al.   EMBO JOURNAL

Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1

(2008) Arowu R. Tanaka et al.   GENES TO CELLS

Contribution of the Mevalonate and Methylerythritol Phosphate Pathways to the Biosynthesis of Dolichols in Plants

(2008) Karolina Skorupinska-Tudek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY