Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

(2013) Kari Ann Shirey et al.   NATURE

Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ

(2012) Victoria J. Hammond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of 15-lipoxygenase in the inflammatory arthritis

(2012) Ming-Yueh Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Microparticles in physiological and in pathological conditions

(2010) Maria Augusta Roos et al.   CELL BIOCHEMISTRY AND FUNCTION

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

(2010) Emmanuel Lorne et al.   INTENSIVE CARE MEDICINE

Ligand docking and binding site analysis with PyMOL and Autodock/Vina

(2010) Daniel Seeliger et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Oxidized Phospholipids Are More Potent Antagonists of Lipopolysaccharide than Inducers of Inflammation

(2010) O. V. Oskolkova et al.   JOURNAL OF IMMUNOLOGY

Crystal Structure of Mouse MD-1 with Endogenous Phospholipid Bound in Its Cavity

(2010) Hitomi Harada et al.   JOURNAL OF MOLECULAR BIOLOGY

HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production

(2010) Rakel Carpintero et al.   PLoS One

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Crystal structure of soluble MD-1 and its interaction with lipid IVa

(2010) S.-i. Yoon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

Local Interleukin-1-Driven Joint Pathology Is Dependent on Toll-Like Receptor 4 Activation

(2009) Shahla Abdollahi-Roodsaz et al.   AMERICAN JOURNAL OF PATHOLOGY

Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis

(2009) I. C. van Eijk et al.   ANNALS OF THE RHEUMATIC DISEASES

Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2009) Rao Muralikrishna Adibhatla et al.   ANTIOXIDANTS & REDOX SIGNALING

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Free Thiol Group of MD-2 as the Target for Inhibition of the Lipopolysaccharide-induced Cell Activation

(2009) Mateja Manček-Keber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Roles of Hydrophobic Residues in Both MD-2 and Toll-like Receptor 4 in Activation by Endotoxin

(2009) Nuša Resman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylethanolamine-esterified Eicosanoids in the Mouse

(2009) Alwena H. Morgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Role of Inflammation in Atherosclerosis Associated with Rheumatoid Arthritis

(2008) Peter Libby   AMERICAN JOURNAL OF MEDICINE

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

(2008) Craig S. Nunemaker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Lipid, protein, DNA oxidation and antioxidant status in rheumatoid arthritis

(2008) Arzu Seven et al.   CLINICAL BIOCHEMISTRY

Oxidized Phospholipid Inhibition of Toll-like Receptor (TLR) Signaling Is Restricted to TLR2 and TLR4

(2008) Clett Erridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidized LDL and anti‐oxLDL antibody levels in peripheral atherosclerotic disease

(2008) Gülnur Andican et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION