Editorial Material
Hematology
Aziz Nazha
Summary: In this issue of Blood, Matek et al developed a computer vision model that can differentiate between bone marrow cell morphologies on a large, expert annotated dataset.
Review
Cell Biology
Qian Li, Nengxian Shi, Chen Cai, Mingming Zhang, Jing He, Ying Tan, Weijun Fu
Summary: Pyroptosis is a gene-regulated cell death process dependent on Caspase, which leads to the production of proinflammatory mediators. Mitochondria also play a crucial role in cell death, with mitochondrial outer membrane permeabilization being a key mechanism. Investigating the roles of mitochondria in pyroptosis can provide new strategies for regulating cell death with potential clinical benefits.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Psychology, Multidisciplinary
Lucas Morillo-Mendez, Rebecca Stower, Alex Sleat, Tim Schreiter, Iolanda Leite, Oscar Martinez Mozos, Martien G. S. Schrooten
Summary: Mentalizing, the ability to infer the mental states of others, has been found to play a role in human-robot interaction, specifically in gaze following. This study manipulated mental state attribution during a gaze cueing task and found that the effect of gaze cueing was reduced when participants perceived the robot as unable to see the screens. These results contribute to the understanding of social cognition and human-robot interaction.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Physiology
Dan Wu, Enny Kampmann, Geng Qian
Summary: MDPs are bioactive peptides encoded by small sORFs within mtDNA genes, playing a protective role in maintaining mitochondrial function and cell viability against metabolic stress. Clinical and experimental studies have shown that MDPs regulate glucose homeostasis, immune responses, mitochondrial function, and stress responses, suggesting their potential in the treatment of cardiovascular diseases.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Computer Science, Information Systems
Monica Lestari Paramita, Kalia Orphanou, Evgenia Christoforou, Jahna Otterbacher, Frank Hopfgartner
Summary: When using Google image search for Covid-19 information, users may see different content based on variations in information needs, geo-locations, and query languages.
INFORMATION PROCESSING & MANAGEMENT
(2021)
Article
Neurosciences
Heeseung Yu, Eunkyoung Han
Summary: This study investigated the selective exposure and confirmation bias of participants in choosing political videos and whether their political positions changed after watching videos that either supported or opposed their positions. Participants completed questionnaires and selected thumbnails of videos before watching, while their brain wave activity was measured. Results showed selective exposure in video thumbnail selection and confirmation bias in questionnaire responses, indicating a hardening of positions. There were significant differences in brain wave activity depending on the consistency between participants and the videos. Future research can expand beyond college students and Asia, and longitudinal studies can determine if patterns remain constant over time.
COGNITIVE NEURODYNAMICS
(2023)
Article
Physics, Applied
Mingyang Ni, Huaxia Deng, Xingzhi Xiao, Yu Cai, Xinglong Gong
Summary: Traditional imaging technology provides images that resemble human vision for post-information acquisition and interpretation. This Letter proposes a feature single-pixel imaging technique that allows for direct imaging of specific features without traditional image processing methods. This research offers a significant advancement in single-pixel imaging for feature information acquisition and has immense potential for applications in various industries and daily life scenarios.
APPLIED PHYSICS LETTERS
(2023)
Article
Physiology
Jing Zhang, Feng Zhang, Yanou Wang
Summary: Diabetic cardiomyopathy is associated with mitochondrial damage, specifically due to increased mitochondria-endoplasmic reticulum (ER) contact. Hyperglycemia induces this contact in cardiomyocytes, but silencing of Mfn2 can protect against mitochondrial dysfunction, calcium overload, apoptosis, and ER stress, enhancing cardiomyocyte survival under high-glucose conditions.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biochemical Research Methods
Chaitanya Chintaluri, Marta Bejtka, Wladyslaw Sredniawa, Michal Czerwinski, Jakub M. Dzik, Joanna Jedrzejewska-Szmek, Kacper Kondrakiewicz, Ewa Kublik, Daniel K. Wojcik
Summary: This study demonstrates that for any experimental setup and function space of current source densities, it is possible to identify precisely recoverable current source distributions, allowing for improvement in analysis results and interpretation of recorded brain data. By conceptually separating the estimation space from the experimental setup, sources not accessible to standard methods can be recovered.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Education & Educational Research
Kennedy Kam Ho Chan, Lihua Xu, Rebecca Cooper, Amanda Berry, Jan H. van Driel
Summary: Teacher noticing has emerged as a concept in recent years to capture the dynamic and situational aspects of teaching expertise, particularly in mathematics education research. This concept has also been introduced into the science education literature, where studies focus on defining, conceptualizing, and investigating teacher noticing. As teacher noticing has been imported into science education literature, there have been shifts in the original understanding and assumptions about this concept, prompting discussions on how findings from these studies can advance knowledge in science teaching expertise.
STUDIES IN SCIENCE EDUCATION
(2021)
Article
Psychology, Multidisciplinary
Jamal R. Williams, Yuri A. Markov, Natalia A. Tiurina, Viola S. Stormer
Summary: This study found that auditory context plays a critical role in visual object perception, demonstrating that the perceptual experience of visual objects is directly shaped by naturalistic auditory context.
PSYCHOLOGICAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Aurelie Jolivald, Kelly Yarnell, Carol Hall, Carrie Ijichi
Summary: Subjective equine personality questionnaires can effectively predict various outcomes in horses, but assessment tools need to meet criteria such as internal consistency, predictive validity, inter-rater reliability, and test-retest reliability. The Equine Personality Test (EPT) demonstrates internal consistency and high reliability in assessing horses' Agreeableness, Neuroticism, Extroversion, and Gregariousness towards People. However, caution is needed when interpreting the assessment of Gregariousness towards Horses. The reliability of EPT scores can be improved by involving primary caregivers as raters.
APPLIED ANIMAL BEHAVIOUR SCIENCE
(2022)
Review
Health Care Sciences & Services
Tomasz Rechcinski
Summary: The electrocardiogram (ECG) has gained new significance due to its digital recording, frequent use, and the application of artificial intelligence (AI) for processing. This literature review highlights various software tools used to extract new information from the ECG, such as natural language processing, backpropagation neural network, and convolutional neural network. These AI tools enable accurate predictions based on the ECG, including age, sex, abnormal heart valve structure, atrial electrical activity, immune response after transplantation, response to resynchronization therapy, and risk of sudden cardiac death. The simplicity, relatively low cost, and potential for remote examination make these results attractive. The presented studies represent only a fraction of the advancements expected in the current year.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Neurosciences
Diane Rekow, Jean-Yves Baudouin, Karine Durand, Arnaud Leleu
Summary: Visual categorization is the brain's ability to respond rapidly to certain category of inputs, and it might be influenced by odors. The experiment found that odor can enhance the response to ambiguous face-like objects, but it has no significant effect on other category-selective responses or general visual response. These findings suggest that the brain actively uses cues from different senses to categorize visual inputs, and olfaction can disambiguate visual information effectively.
Article
Chemistry, Physical
Shirong Qiang, Jingjing Wang, Yun Wang, Longmiao Yuan, Leiping Shi, Zhe Ding, Wei Wang, Jianjun Liang, Ping Li, Qiaohui Fan
Summary: X-ray photoelectron spectroscopy (XPS) is a useful technique for identifying the state of elements, but the effects of X-ray irradiation on the chemical state change are sometimes overlooked. This study reveals the negative shift in U 4f spectra induced by X-ray irradiation during XPS detection and suggests methods to reduce potential errors. The findings highlight the importance of considering X-ray induced alterations in chemical states when using X-ray techniques.
APPLIED SURFACE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Soyoung Hwang, Jung Yun Kang, Min Jae Kim, Dong Min Shin, Jeong Hee Hong
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2019)
Article
Gastroenterology & Hepatology
Aran Son, Malini Ahuja, Daniella M. Schwartz, Arpad Varga, William Swaim, Namju Kang, Jozsef Maleth, Dong Min Shin, Shmuel Muallem
Article
Endocrinology & Metabolism
Aran Son, Namju Kang, Sue Young Oh, Ki Woo Kim, Shmuel Muallem, Yu-Mi Yang, Dong Min Shin
JOURNAL OF ENDOCRINOLOGY
(2019)
Review
Biochemistry & Molecular Biology
Jung Yun Kang, Namju Kang, Yu-Mi Yang, Jeong Hee Hong, Dong Min Shin
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Pharmacology & Pharmacy
Soyoung Hwang, Dong Min Shin, Jeong Hee Hong
Article
Medicine, Research & Experimental
Ji Su Sun, Dong Joo Yang, Ann W. Kinyua, Seul Gi Yoon, Je Kyung Seong, Juwon Kim, Seok Jun Moon, Dong Min Shin, Yun-Hee Choi, Ki Woo Kim
Summary: The dysfunction of primary cilia in the ventromedial hypothalamus is linked to impaired energy and skeletal homeostasis, resulting in obesity and increased bone density. Dysfunction of VMH primary cilia leads to decreased sympathetic activation and central leptin resistance, impacting energy expenditure and bone metabolism.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Cell Biology
Soyoung Hwang, Peter Chang-Whan Lee, Dong Min Shin, Jeong Hee Hong
Summary: Spinophilin plays a crucial role in modulating the junctional network and cellular migration in lung cancer cells, affecting invasive ability and transporter activity.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Sue Young Oh, Namju Kang, Jung Yun Kang, Ki Woo Kim, Jong-Hoon Choi, Yu-Mi Yang, Dong Min Shin
Summary: This study revealed that Sestrin2 plays a crucial role in bone homeostasis and osteoclast differentiation by regulating NFATc1 and the TRAF6/p62 interaction in the RANKL-RANK-TRAF6 signaling pathway. The deletion of Sestrin2 led to a decrease in osteoclast differentiation and function, as well as reduced bone mass, suggesting its novel role in bone metabolism.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Hyun Jin Kim, Jiae Lee, Gong-Rak Lee, Narae Kim, Hye In Lee, Minjeong Kwon, Nam Young Kim, Jin Ha Park, Ye Hee Kang, Hyeong Ju Song, TaeSoo Kim, Dong Min Shin, Woojin Jeong
Summary: FN inhibits osteoclastogenesis by blocking CaMKIV and calcineurin, reducing the risk of bone diseases like osteoporosis.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sukjoon Lee, Dongzi Chen, Munsu Park, Sunil Kim, Yoon Jeong Choi, Seok Jun Moon, Dong Min Shin, Ji Hyun Lee, Euiseong Kim
Summary: Single-cell RNA sequencing revealed distinct gene expression patterns in specific clusters of human dental pulp stem cells (hDPSCs) and human periodontal ligament stem cells (hPDLSCs). hDPSCs exhibited osteogenic and neurogenic cell populations, while hPDLSCs mainly comprised osteogenic and myofibroblastic populations. The results can serve as valuable resources for further research in dental therapeutics.
JOURNAL OF ENDODONTICS
(2022)
Article
Toxicology
Dongun Lee, Peter Chang-Whan Lee, Jeong Hee Hong, Dong Min Shin
Summary: The study found that 8-estradiol treatment attenuated the oxalate or bicarbonate transporting activities through SLC26A6 and enhanced cancer cell migration. Even in the presence of 8-estradiol treatment, increased SLC26A6 expression weakened cellular migration. These results suggest that 8-estradiol treatment enhances cancer cell migration by inhibiting SLC26A6 activity.
TOXICOLOGY IN VITRO
(2022)
Article
Multidisciplinary Sciences
Seul Ki Kim, Le Trung Tran, Cherl NamKoong, Hyung Jin Choi, Hye Jin Chun, Yong-ho Lee, MyungHyun Cheon, ChiHye Chung, Junmo Hwang, Hyun-Ho Lim, Dong Min Shin, Yun-Hee Choi, Ki Woo Kim
Summary: Small humanin-like peptide 2 (SHLP2), a mitochondrial-derived peptide, plays a crucial role in energy homeostasis. The study demonstrates that SHLP2 can protect mice from high-fat diet-induced obesity and improve insulin sensitivity. It activates pro-opiomelanocortin (POMC) neurons in the hypothalamus, which suppresses food intake and promotes thermogenesis. The researchers also discover that SHLP2 binds to and activates chemokine receptor 7 (CXCR7).
NATURE COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Minjeong Ji, Hee Jung Ryu, Hyeon-Man Baek, Dong Min Shin, Jeong Hee Hong
Summary: The study found that modulation of the migratory module of fibroblast-like synoviocytes (FLSs) can attenuate the severity of rheumatoid arthritis (RA). The sodium bicarbonate cotransporter n1 (NBCn1) was identified in RA-FLSs and inhibiting NBCs reduced FLS migration and RA symptoms.
EXPERIMENTAL AND MOLECULAR MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Soyoung Hwang, Dong Min Shin, Jeong Hee Hong
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Pharmacology & Pharmacy
Namju Kang, Ki Woo Kim, Dong Min Shin
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
(2019)