SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation

Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways

(2011) C. Richardson et al.   JOURNAL OF CELL SCIENCE

Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization

(2010) Nicolas Dzamko et al.   BIOCHEMICAL JOURNAL

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

(2010) R. Jeremy Nichols et al.   BIOCHEMICAL JOURNAL

Role of the WNK-activated SPAK kinase in regulating blood pressure

(2010) Fatema H. Rafiqi et al.   EMBO Molecular Medicine

SPAK-Knockout Mice Manifest Gitelman Syndrome and Impaired Vasoconstriction

(2010) S.-S. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Carriers of Recessive WNK1/HSN2 Mutations for Hereditary Sensory and Autonomic Neuropathy Type 2 (HSAN2) Are More Sensitive to Thermal Stimuli

(2009) M. L. Loggia et al.   JOURNAL OF NEUROSCIENCE

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

(2008) Eric Delpire et al.   BIOCHEMICAL JOURNAL

Cotransporters, WNKs and hypertension: an update

(2008) Peter W Flatman   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

(2008) C. Richardson et al.   JOURNAL OF CELL SCIENCE

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

(2008) C. Richardson et al.   JOURNAL OF CELL SCIENCE

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

(2008) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA