DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome

Exploring Off-Targets and Off-Systems for Adverse Drug Reactions via Chemical-Protein Interactome — Clozapine-Induced Agranulocytosis as a Case Study

(2011) Lun Yang et al.   PLoS Computational Biology

The Chemical Basis of Pharmacology

(2010) Michael J. Keiser et al.   BIOCHEMISTRY

Structure-Based Approaches to Target Fishing and Ligand Profiling

(2010) Didier Rognan   Molecular Informatics

Evaluation of Phenoxybenzamine in the CFA Model of Pain following Gene Expression Studies and Connectivity Mapping

(2010) Meiping Chang et al.   Molecular Pain

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

(2010)   NATURE BIOTECHNOLOGY

In-Silico Approaches to Multi-target Drug Discovery

(2010) Xiao Hua Ma et al.   PHARMACEUTICAL RESEARCH

Quality check of spontaneous adverse drug reaction reporting forms of different countries

(2010) M. S. Bandekar et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements

(2010) Enrico De Franchi et al.   PLoS One

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of systems pharmacology in understanding drug adverse events

(2010) Seth I. Berger et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

A CitationRank algorithm inheriting Google technology designed to highlight genes responsible for serious adverse drug reaction

(2009) Lun Yang et al.   BIOINFORMATICS

Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses

(2009) A P Chiang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The value of drug repositioning in the current pharmaceutical market

(2009) E.L. Tobinick   DRUG NEWS & PERSPECTIVES

Building a drug–target network and its applications

(2009) Soyoung Lee et al.   Expert Opinion on Drug Discovery

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Mechanisms of drug combinations: interaction and network perspectives

(2009) Jia Jia et al.   NATURE REVIEWS DRUG DISCOVERY

SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical–protein interactome

(2009) Lun Yang et al.   NUCLEIC ACIDS RESEARCH

Human Disease-Drug Network Based on Genomic Expression Profiles

(2009) Guanghui Hu et al.   PLoS One

Cancer informatics for the clinician: An interaction database for chemotherapy regimens and antiepileptic drugs

(2009) Kevin Yi-Lwern Yap et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

(2009) Lun Yang et al.   PLoS Computational Biology