Cholesterol depletion enhances TGF-β Smad signaling by increasing c-Jun expression through a PKR-dependent mechanism

Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility

(2017) Erine H. Budi et al.   TRENDS IN CELL BIOLOGY

Differential regulation of translation and endocytosis of alternatively spliced forms of the type II bone morphogenetic protein (BMP) receptor

(2016) Ayelet R. Amsalem et al.   MOLECULAR BIOLOGY OF THE CELL

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

(2016) Sebastian Zimmer et al.   Science Translational Medicine

Signaling Receptors for TGF-β Family Members

(2016) Carl-Henrik Heldin et al.   Cold Spring Harbor Perspectives in Biology

The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins

(2016) Andrew D. Rouillard et al.   Database-The Journal of Biological Databases and Curation

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

(2016) Aristidis Moustakas et al.   Journal of Clinical Medicine

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

(2015) Erine H. Budi et al.   Science Signaling

Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism

(2015) Vasundhara Kain et al.   Scientific Reports

A Critical Role for PKR Complexes with TRBP in Immunometabolic Regulation and eIF2α Phosphorylation in Obesity

(2015) Takahisa Nakamura et al.   Cell Reports

ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

(2015) Baby Periyanayaki Muthusamy et al.   PLOS BIOLOGY

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

(2015) Erine H. Budi et al.   Science Signaling

Disorders of Cholesterol Metabolism and Their Unanticipated Convergent Mechanisms of Disease

(2014) Frances M. Platt et al.   Annual Review of Genomics and Human Genetics

Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

(2014) Lei Qiang et al.   Autophagy

Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β

(2014) Keren E. Shapira et al.   MOLECULAR BIOLOGY OF THE CELL

The role of palmitoylation in regulating Ras localization and function

(2013) Sharon Eisenberg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular Pathways: Sterols and Receptor Signaling in Cancer

(2013) L. Gabitova et al.   CLINICAL CANCER RESEARCH

The role of signalling in cellular cholesterol homeostasis

(2013) Winnie Luu et al.   IUBMB LIFE

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of cholesterol biosynthesis and cancer signaling

(2012) Andrey Gorin et al.   CURRENT OPINION IN PHARMACOLOGY

Regulation of EMT by TGFβ in cancer

(2012) Carl-Henrik Heldin et al.   FEBS LETTERS

Oligomeric interactions of TGF-β and BMP receptors

(2012) Marcelo Ehrlich et al.   FEBS LETTERS

Post-translational regulation of TGF-β receptor and Smad signaling

(2012) Pinglong Xu et al.   FEBS LETTERS

Coated Pit-mediated Endocytosis of the Type I Transforming Growth Factor-β (TGF-β) Receptor Depends on a Di-leucine Family Signal and Is Not Required for Signaling

(2012) Keren E. Shapira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Getting ‘Smad’ about obesity and diabetes

(2012) C K Tan et al.   Nutrition & Diabetes

Regulation of cholesterol homeostasis

(2011) Leigh Goedeke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern

(2011) S. Eisenberg et al.   MOLECULAR AND CELLULAR BIOLOGY

Lowering LDL cholesterol reduces atherosclerotic risk in patients with chronic kidney disease

(2011) Gregory B. Lim   Nature Reviews Cardiology

Roles for the type III TGF-β receptor in human cancer

(2010) Catherine E. Gatza et al.   CELLULAR SIGNALLING

Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

(2010) Anton I. Rosenbaum et al.   JOURNAL OF NEUROCHEMISTRY

Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity

(2009) Shomyseh Sanjabi et al.   CURRENT OPINION IN PHARMACOLOGY

The regulation of TGF  signal transduction

(2009) A. Moustakas et al.   DEVELOPMENT

Role of the 5′-untranslated region in regulating translational efficiency of specific mRNAs in adult cardiocytes

(2009) Laura S. Spruill et al.   FASEB JOURNAL

Inhibitors of clathrin-dependent endocytosis enhance TGF  signaling and responses

(2009) C.-L. Chen et al.   JOURNAL OF CELL SCIENCE

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nucleocytoplasmic shuttling of Smad proteins

(2008) Caroline S Hill   CELL RESEARCH

To (TGF)β or not to (TGF)β: Fine-tuning of Smad signaling via post-translational modifications

(2008) Katharine H. Wrighton et al.   CELLULAR SIGNALLING

Specific Activation of Mitogen-activated Protein Kinase by Transforming Growth Factor-β Receptors in Lipid Rafts Is Required for Epithelial Cell Plasticity

(2008) Wei Zuo et al.   MOLECULAR BIOLOGY OF THE CELL

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY