The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks

(2012) Timothy S. Gomez et al.   MOLECULAR BIOLOGY OF THE CELL

The roles of flotillin microdomains - endocytosis and beyond

(2011) G. P. Otto et al.   JOURNAL OF CELL SCIENCE

The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading

(2011) Gary J. Doherty et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of the MVB Pathway by SCAMP3

(2011) Thomas Falguières et al.   TRAFFIC

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

SNX-BAR-Mediated Endosome Tubulation is Co-ordinated with Endosome Maturation

(2011) Jan R.T. van Weering et al.   TRAFFIC

HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion

(2010) Aftab Taiyab et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

(2010) Srikumar M. Raja et al.   CANCER BIOLOGY & THERAPY

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

A dual role for ErbB2 signaling in cardiac trabeculation

(2010) J. Liu et al.   DEVELOPMENT

Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis

(2010) Marcel Mettlen et al.   JOURNAL OF CELL BIOLOGY

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

(2010) Mark T. Howes et al.   JOURNAL OF CELL BIOLOGY

The endocytic matrix

(2010) Giorgio Scita et al.   NATURE

Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases

(2009) Jasmine V. Abella et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GRAF1-dependent endocytosis: Figure 1

(2009) Gary J. Doherty et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Geldanamycin and its anti-cancer activities

(2009) Yayoi Fukuyo et al.   CANCER LETTERS

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Rab11a and HSP90 Regulate Recycling of Extracellular  -Synuclein

(2009) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Evolving novel anti-HER2 strategies

(2009) Kellie L Jones et al.   LANCET ONCOLOGY

Expression of Epidermal Growth Factor Receptor or ErbB3 Facilitates Geldanamycin-Induced Down-Regulation of ErbB2

(2009) N. M. Pedersen et al.   MOLECULAR CANCER RESEARCH

At the crossroads of polarity, proliferation and apoptosis: The use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression

(2009) Thomas Vaccari et al.   Molecular Oncology

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: Relevance of receptor endocytosis

(2009) T. Ben-Kasus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The GTPase-Activating Protein GRAF1 Regulates the CLIC/GEEC Endocytic Pathway

(2008) Richard Lundmark et al.   CURRENT BIOLOGY

Publisher's Note

(2008)   EXPERIMENTAL CELL RESEARCH

Molecular assemblies and membrane domains in multivesicular endosome dynamics

(2008) Thomas Falguières et al.   EXPERIMENTAL CELL RESEARCH

Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity

(2008) Kirsten Sandvig et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer

(2008) Kirstine Roepstorff et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells

(2008) D. J. Barr et al.   JOURNAL OF CELL SCIENCE

Geldanamycin-Induced Down-Regulation of ErbB2 from the Plasma Membrane Is Clathrin Dependent but Proteasomal Activity Independent

(2008) N. M. Pedersen et al.   MOLECULAR CANCER RESEARCH

Endocytosis and Cancer: an ‘Insider’ Network with Dangerous Liaisons

(2008) Letizia Lanzetti et al.   TRAFFIC