SHIP2 regulates epithelial cell polarity through its lipid product, which binds to Dlg1, a pathway subverted by hepatitis C virus core protein

Interplay among cellular polarization, lipoprotein metabolism and hepatitis C virus entry

(2016) Ignacio Benedicto   WORLD JOURNAL OF GASTROENTEROLOGY

Exome Sequencing Identifies INPPL1 Mutations as a Cause of Opsismodysplasia

(2012) Céline Huber et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration

(2012) Katsuhiro Kato et al.   MOLECULAR BIOLOGY OF THE CELL

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

(2012) Annalisa Bianco et al.   PLoS Pathogens

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2in regulating insulin sensitivity defined by knock-in analysis

(2011) Stephan Wullschleger et al.   BIOCHEMICAL JOURNAL

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

SHIP2 multiple functions: A balance between a negative control of PtdIns(3,4,5)P3level, a positive control of PtdIns(3,4)P2production, and intrinsic docking properties

(2011) Christophe Erneux et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication

(2011) K. L. Berger et al.   JOURNAL OF VIROLOGY

The Host Phosphoinositide 5-Phosphatase SHIP2 Regulates Dissemination of Vaccinia Virus

(2011) S. McNulty et al.   JOURNAL OF VIROLOGY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Metabolomic Profile of Hepatitis C Virus-Infected Hepatocytes

(2011) Barbara Roe et al.   PLoS One

Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes

(2011) P. Cossart   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis c virus and host cell lipids: An intimate connection

(2011) Gualtiero Alvisi et al.   RNA Biology

Phosphoinositides in Cell Architecture

(2011) A. Shewan et al.   Cold Spring Harbor Perspectives in Biology

Membrane Targeting of Bazooka/PAR-3 Is Mediated by Direct Binding to Phosphoinositide Lipids

(2010) Michael P. Krahn et al.   CURRENT BIOLOGY

Hepatitis C Virus: Assembly and Release of Virus Particles

(2010) Daniel M. Jones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

(2010) Eva Herker et al.   NATURE MEDICINE

Assembly of infectious hepatitis C virus particles

(2010) Ralf Bartenschlager et al.   TRENDS IN MICROBIOLOGY

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

(2009) Lisa M. Ooms et al.   BIOCHEMICAL JOURNAL

Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening

(2009) Maud Trotard et al.   FASEB JOURNAL

Protein phosphatase 2A PR130/B″α1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling

(2009) Karen Zwaenepoel et al.   FASEB JOURNAL

Hepatitis C Virus Infection Reduces Hepatocellular Polarity in a Vascular Endothelial Growth Factor–Dependent Manner

(2009) Christopher J. Mee et al.   GASTROENTEROLOGY

PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells

(2009) N. Stenzel et al.   JOURNAL OF CELL SCIENCE

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

(2009) J. Borawski et al.   JOURNAL OF VIROLOGY

Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

(2009) C. J. Mee et al.   JOURNAL OF VIROLOGY

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

(2009) Alexander Ploss et al.   NATURE

Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins

(2009) Vinca Icard et al.   PLoS One

Liver Cancer-Derived Hepatitis C Virus Core Proteins Shift TGF-Beta Responses from Tumor Suppression to Epithelial-Mesenchymal Transition

(2009) Serena Battaglia et al.   PLoS One

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid droplets as dynamic organelles connecting storage and efflux of lipids

(2008) Sven-Olof Olofsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The docking properties of SHIP2 influence both JIP1 tyrosine phosphorylation and JNK activity

(2008) Jingwei Xie et al.   CELLULAR SIGNALLING

Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity

(2008) Wei Yu et al.   EMBO REPORTS

Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum

(2008) Ignacio Benedicto et al.   HEPATOLOGY

Vectorial Entry and Release of Hepatitis A Virus in Polarized Human Hepatocytes

(2008) M. J. Snooks et al.   JOURNAL OF VIROLOGY

Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

(2008) S. Liu et al.   JOURNAL OF VIROLOGY

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Coordinated protein sorting, targeting and distribution in polarized cells

(2008) Ira Mellman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatitis C Virus Core Protein Induces Lipid Droplet Redistribution in a Microtubule- and Dynein-Dependent Manner

(2008) Steeve Boulant et al.   TRAFFIC