HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites

Membrane Fusion: Five Lipids, Four SNAREs, Three Chaperones, Two Nucleotides, and a Rab, All Dancing in a Ring on Yeast Vacuoles

(2010) William Wickner   Annual Review of Cell and Developmental Biology

Membrane Budding

(2010) James H. Hurley et al.   CELL

Multisubunit Tethering Complexes and Their Role in Membrane Fusion

(2010) Cornelia Bröcker et al.   CURRENT BIOLOGY

Structure and mechanism in membrane trafficking

(2010) Frederick M Hughson et al.   CURRENT OPINION IN CELL BIOLOGY

HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion

(2010) Hao Xu et al.   EMBO JOURNAL

Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

(2010) Margarita Cabrera et al.   JOURNAL OF CELL BIOLOGY

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion

(2010) Jingshi Shen et al.   JOURNAL OF CELL BIOLOGY

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly

(2010) Christopher M. Hickey et al.   MOLECULAR BIOLOGY OF THE CELL

The SM protein Vps33 and the t-SNARE Habc domain promote fusion pore opening

(2010) Michel Pieren et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex

(2010) S. S. Rathore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Defined Subunit Arrangement and Rab Interactions Are Required for Functionality of the HOPS Tethering Complex

(2010) Clemens W. Ostrowicz et al.   TRAFFIC

A Structure-Based Mechanism for Vesicle Capture by the Multisubunit Tethering Complex Dsl1

(2009) Yi Ren et al.   CELL

The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p

(2009) M. L. M. Furgason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components

(2009) C. Stroupe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Analysis of DHHC Acyltransferases Implies Overlapping Substrate Specificity and a Two-Step Reaction Mechanism

(2009) Haitong Hou et al.   TRAFFIC

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

(2008) Joji Mima et al.   EMBO JOURNAL

Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

(2008) Christopher L. Brett et al.   JOURNAL OF CELL BIOLOGY

HOPS Proofreads the trans-SNARE Complex for Yeast Vacuole Fusion

(2008) Vincent J. Starai et al.   MOLECULAR BIOLOGY OF THE CELL