Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

Activity of the β-catenin phosphodestruction complex at cell–cell contacts is enhanced by cadherin-based adhesion

(2009) Meghan T. Maher et al.   JOURNAL OF CELL BIOLOGY

Contribution of the 15 amino acid repeats of truncated APC to β-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients

(2009) E M Kohler et al.   ONCOGENE

Wnt Signaling from Development to Disease: Insights from Model Systems

(2009) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis

(2009) Claudia Gaspar et al.   PLoS Genetics

Cell regulation by the Apc protein

(2008) Brooke M McCartney et al.   CURRENT OPINION IN CELL BIOLOGY

Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo

(2008) Wynne Peterson-Nedry et al.   DEVELOPMENTAL BIOLOGY

Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

 -Catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

APC Is Essential for Targeting Phosphorylated β-Catenin to the SCFβ-TrCP Ubiquitin Ligase

(2008) YunYun Su et al.   MOLECULAR CELL

Recruitment of adenomatous polyposis coli and β-catenin to axin-puncta

(2008) M C Faux et al.   ONCOGENE

Dual Positive and Negative Regulation of Wingless Signaling by Adenomatous Polyposis Coli

(2008) C. M. Takacs et al.   SCIENCE