标题
Structural basis for RNA replication by the hepatitis C virus polymerase
作者
关键词
-
出版物
SCIENCE
Volume 347, Issue 6223, Pages 771-775
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2015-02-13
DOI
10.1126/science.1259210
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Review article: the efficacy and safety of sofosbuvir, a novel, oral nucleotide NS5B polymerase inhibitor, in the treatment of chronic hepatitis C virus infection
- (2014) R. S. Koff ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance
- (2014) Angela M. Lam et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development
- (2014) Célia Caillet-Saguy et al. ANTIVIRAL RESEARCH
- Infrequent Development of Resistance in Genotype 1–6 Hepatitis C Virus–Infected Subjects Treated With Sofosbuvir in Phase 2 and 3 Clinical Trials
- (2014) Evguenia S. Svarovskaia et al. CLINICAL INFECTIOUS DISEASES
- OPTN/SRTR 2012 Annual Data Report: Liver
- (2013) W. R. Kim et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C
- (2013) Edward J. Gane et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genotype and Subtype Profiling of PSI-7977 as a Nucleotide Inhibitor of Hepatitis C Virus
- (2012) Angela M. Lam et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Treating hepatitis C: current standard of care and emerging direct-acting antiviral agents
- (2012) F. Poordad et al. JOURNAL OF VIRAL HEPATITIS
- Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
- (2012) R. T. Mosley et al. JOURNAL OF VIROLOGY
- Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405
- (2012) N. Scrima et al. JOURNAL OF VIROLOGY
- A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes
- (2011) M. Schmitt et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus Nucleotide Inhibitors PSI-352938 and PSI-353661 Exhibit a Novel Mechanism of Resistance Requiring Multiple Mutations within Replicon RNA
- (2011) A. M. Lam et al. JOURNAL OF VIROLOGY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PSI-7851, a Pronucleotide of -D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication
- (2010) A. M. Lam et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977
- (2010) Eisuke Murakami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
- (2010) Déborah Harrus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
- (2010) Michael J. Sofia et al. JOURNAL OF MEDICINAL CHEMISTRY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase
- (2009) P. Simister et al. JOURNAL OF VIROLOGY
- Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients
- (2008) S. Le Pogam et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Structural Insights into Mechanisms of Catalysis and Inhibition in Norwalk Virus Polymerase
- (2008) Dmitry F. Zamyatkin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search