Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitochondrion-Targeted Nuclear Genes

Mechanical Unloading Promotes Myocardial Energy Recovery in Human Heart Failure

(2014) A. A. Gupte et al.   Circulation-Cardiovascular Genetics

Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function

(2014) Renata O. Pereira et al.   FASEB JOURNAL

mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

(2013) Masahiro Morita et al.   Cell Metabolism

mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

(2013) Kenta Masui et al.   Cell Metabolism

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

(2013) Yang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical Unloading Activates FoxO3 to Trigger Bnip3‐Dependent Cardiomyocyte Atrophy

(2013) Dian J. Cao et al.   Journal of the American Heart Association

Inducible Overexpression of GLUT1 Prevents Mitochondrial Dysfunction and Attenuates Structural Remodeling in Pressure Overload but Does Not Prevent Left Ventricular Dysfunction

(2013) Renata O. Pereira et al.   Journal of the American Heart Association

Integration of cellular bioenergetics with mitochondrial quality control and autophagy

(2012) Bradford G. Hill et al.   BIOLOGICAL CHEMISTRY

AMP-Activated Protein Kinase Regulation and Biological Actions in the Heart

(2012) Vlad G. Zaha et al.   CIRCULATION RESEARCH

Cardiac PI3K-Akt Impairs Insulin-Stimulated Glucose Uptake Independent of mTORC1 and GLUT4 Translocation

(2012) Yi Zhu et al.   MOLECULAR ENDOCRINOLOGY

PTEN/Akt Signaling Controls Mitochondrial Respiratory Capacity through 4E-BP1

(2012) Chong Kiat Goo et al.   PLoS One

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

(2011) E. D. Abel et al.   CARDIOVASCULAR RESEARCH

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy

(2011) Christian Riehle et al.   CIRCULATION RESEARCH

Regulation of Foxo-Dependent Transcription by Post-Translational Modifications

(2011) Marco Boccitto et al.   CURRENT DRUG TARGETS

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

(2011) C. Sloan et al.   DIABETES

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor

(2010) Jessica Perez et al.   BIOCHEMICAL JOURNAL

FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress

(2010) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective effects of AMP-activated protein kinase in the cardiovascular system

(2010) Qiang Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

(2010) Ippei Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy

(2009) Jaya Krishnan et al.   Cell Metabolism

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

(2009) H. Bugger et al.   DIABETES

The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors

(2009) Ahmed Essaghir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

(2008) Yasuhiro Izumiya et al.   Cell Metabolism

O-GlcNAc Regulates FoxO Activation in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy

(2008) Jaetaek Kim et al.   MOLECULAR ENDOCRINOLOGY

The FoxO code

(2008) D R Calnan et al.   ONCOGENE