Extracellular Heat Shock Protein 90 Signals through Subdomain II and the NPVY Motif of LRP-1 Receptor to Akt1 and Akt2: a Circuit Essential for Promoting Skin Cell Migration In Vitro and Wound Healing In Vivo

Exploiting PI3K/mTOR signaling to accelerate epithelial wound healing

(2013) RM Castilho et al.   ORAL DISEASES

MicroRNA-99 Family Targets AKT/mTOR Signaling Pathway in Dermal Wound Healing

(2013) Yi Jin et al.   PLoS One

Spermatogenesis arrest caused by conditional deletion of Hsp90α in adult mice

(2012) Chiaki Kajiwara et al.   Biology Open

Secreted heat shock protein-90 (Hsp90) in wound healing and cancer

(2011) Wei Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing

(2011) L. Feldmeyer et al.   BRITISH JOURNAL OF DERMATOLOGY

A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice

(2011) Chieh-Fang Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway

(2011) Young Woo Kim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α–positive tumors

(2011) Divya Sahu et al.   MOLECULAR BIOLOGY OF THE CELL

The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse

(2011) Iwona Grad et al.   PLoS One

A Novel Extracellular Hsp90 Mediated Co-Receptor Function for LRP1 Regulates EphA2 Dependent Glioblastoma Cell Invasion

(2011) Udhayakumar Gopal et al.   PLoS One

Extracellular Heat Shock Protein (Hsp)70 and Hsp90α Assist in Matrix Metalloproteinase-2 Activation and Breast Cancer Cell Migration and Invasion

(2011) Jessica D. Sims et al.   PLoS One

Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells

(2011) T. Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular heat shock protein HSP90β secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-β1

(2010) Shigeki Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits

(2010) Dimitris Stellas et al.   BMC CELL BIOLOGY

Distinct Biological Roles for the Akt Family in Mammary Tumor Progression: Figure 1.

(2010) Rachelle L. Dillon et al.   CANCER RESEARCH

Secreted Heat Shock Protein 90α Induces Colorectal Cancer Cell Invasion through CD91/LRP-1 and NF-κB-mediated Integrin αVExpression

(2010) Jinn-Shiun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated Wound Healing by mTOR Activation in Genetically Defined Mouse Models

(2010) Cristiane H. Squarize et al.   PLoS One

MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1

(2009) Heesang Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90  autocrine signaling to promote keratinocyte migration

(2009) D. T. Woodley et al.   JOURNAL OF CELL SCIENCE

Dysregulation of the mTOR Pathway Secondary to Mutations or a Hostile Microenvironment Contributes to Cancer and Poor Wound Healing

(2009) Richard A.F. Clark et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY