Regulation of Feedback between Protein Kinase A and the Proteasome System Worsens Huntington's Disease

Phosphorylation of Rpt6 Regulates Synaptic Strength in Hippocampal Neurons

(2012) S. N. Djakovic et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Growth of New Dendritic Spines Is Regulated by the Proteasome

(2012) Andrew M. Hamilton et al.   NEURON

When Cytokinin, a Plant Hormone, Meets the Adenosine A2A Receptor: A Novel Neuroprotectant and Lead for Treating Neurodegenerative Disorders?

(2012) Yi-Chao Lee et al.   PLoS One

A deconvolution method to improve automated 3D-analysis of dendritic spines: application to a mouse model of Huntington’s disease

(2011) Nicolas Heck et al.   Brain Structure & Function

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

(2011) Albert Giralt et al.   HUMAN MOLECULAR GENETICS

Gastrodia elata prevents huntingtin aggregations through activation of the adenosine A2A receptor and ubiquitin proteasome system

(2011) Chuen-Lin Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

A New Drug Design Targeting the Adenosinergic System for Huntington's Disease

(2011) Nai-Kuei Huang et al.   PLoS One

Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines

(2010) Baris Bingol et al.   CELL

Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments

(2010) Xiang Li et al.   HUMAN MOLECULAR GENETICS

Huntington's disease: From molecular basis to therapeutic advances

(2010) Sylvia Krobitsch et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity

(2010) Xiaonan H. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute Polyglutamine Expression in Inducible Mouse Model Unravels Ubiquitin/Proteasome System Impairment and Permanent Recovery Attributable to Aggregate Formation

(2010) Z. Ortega et al.   JOURNAL OF NEUROSCIENCE

A Role for the Ubiquitin-Proteasome System in Activity-Dependent Presynaptic Silencing

(2010) X. Jiang et al.   JOURNAL OF NEUROSCIENCE

A2A receptor knockout worsens survival and motor behaviour in a transgenic mouse model of Huntington's disease

(2010) Stéphane Mievis et al.   NEUROBIOLOGY OF DISEASE

Inhibition of the Striatal Specific Phosphodiesterase PDE10A Ameliorates Striatal and Cortical Pathology in R6/2 Mouse Model of Huntington's Disease

(2010) Carmela Giampà et al.   PLoS One

CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

(2010) Eva Benito et al.   TRENDS IN NEUROSCIENCES

The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin–proteasome system

(2009) Ming-Chang Chiang et al.   HUMAN MOLECULAR GENETICS

Non-proteolytic Regulation of p53-mediated Transcription through Destabilization of the Activator·Promoter Complex by the Proteasomal ATPases

(2009) Young-Chan Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin-Proteasome Reporter GFPu Does Not Accumulate in Neurons of the R6/2 Transgenic Mouse Model of Huntington's Disease

(2009) John S. Bett et al.   PLoS One

The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease

(2009) Kevin St.P. Mcnaught et al.   SYNAPSE

A Critical Evaluation of Adenosine A2A Receptors as Potentially “Druggable” Targets in Huntingtons Disease

(2008) Patrizia Popoli et al.   CURRENT PHARMACEUTICAL DESIGN

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

(2008) Jianjun Wang et al.   JOURNAL OF CELL BIOLOGY

PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts

(2008) Mitsutoshi Asai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sumoylation of Specificity Protein 1 Augments Its Degradation by Changing the Localization and Increasing the Specificity Protein 1 Proteolytic Process

(2008) Yi-Ting Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Expanded-Polyglutamine Huntingtin Protein Suppresses the Secretion and Production of a Chemokine (CCL5/RANTES) by Astrocytes

(2008) S.-Y. Chou et al.   JOURNAL OF NEUROSCIENCE

Comparative Study of Anti-hepatitis B Virus RNA Interference by Double-stranded Adeno-associated Virus Serotypes 7, 8, and 9

(2008) Chun-Chi Chen et al.   MOLECULAR THERAPY

Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

(2008) Hwan-Ching Tai et al.   NATURE REVIEWS NEUROSCIENCE