The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats

High glucose modifies transient receptor potential canonical type 6 channels via increased oxidative stress and syndecan-4 in human podocytes

(2014) Florian Thilo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vitamin D Down-Regulates TRPC6 Expression in Podocyte Injury and Proteinuric Glomerular Disease

(2013) Ramon Sonneveld et al.   AMERICAN JOURNAL OF PATHOLOGY

High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species

(2013) Bing-Chen Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes

(2013) Z. Li et al.   CELL PROLIFERATION

25 (OH) Vitamin D Levels and Renal Disease Progression in Patients with Type 2 Diabetic Nephropathy and Blockade of the Renin-Angiotensin System

(2013) G. Fernandez-Juarez et al.   Clinical Journal of the American Society of Nephrology

Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats

(2013) Ming-Ming Pan et al.   FOOD AND CHEMICAL TOXICOLOGY

Novel Role of NOD2 in Mediating Ca 2+ Signaling

(2013) Huirong Han et al.   HYPERTENSION

Prevalence and Control of Diabetes in Chinese Adults

(2013) Yu Xu   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nuclear Factor κB Mediates Suppression of Canonical Transient Receptor Potential 6 Expression by Reactive Oxygen Species and Protein Kinase C in Kidney Cells

(2013) Yanxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gain-of-function Mutations in Transient Receptor Potential C6 (TRPC6) Activate Extracellular Signal-regulated Kinases 1/2 (ERK1/2)

(2013) David Chiluiza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiotensin II Activation of TRPC6 Channels in Rat Podocytes Requires Generation of Reactive Oxygen Species

(2013) Marc Anderson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vitamin D Receptor Signaling in Podocytes Protects against Diabetic Nephropathy

(2012) Y. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis

(2012) Hikaru Sugimoto et al.   NATURE MEDICINE

Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes

(2011) Sarabeth Graham et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)2vitamin D3: Genomic and non-genomic mechanisms

(2011) Mark R. Haussler et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

2α-Methyl-19-nor-(20S)-1,25-dihydroxyvitamin D3 protects the insulin 2 knockout non-obese diabetic mouse from developing type 1 diabetes without hypercalcaemia

(2011) C. M. Kiekhaefer et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

TRPC6 Enhances Angiotensin II-induced Albuminuria

(2011) J. Eckel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Blockade of Wnt/ -Catenin Signaling by Paricalcitol Ameliorates Proteinuria and Kidney Injury

(2010) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial

(2010) Dick de Zeeuw et al.   LANCET

Proteinuria, the Podocyte, and Insulin Resistance

(2010) Alessia Fornoni   NEW ENGLAND JOURNAL OF MEDICINE

1,25-Dihydroxyvitamin D3 Prevents Puromycin Aminonucleoside-Induced Apoptosis of Glomerular Podocytes by Activating the Phosphatidylinositol 3-Kinase/Akt-Signaling Pathway

(2009) Houqin Xiao et al.   AMERICAN JOURNAL OF NEPHROLOGY

TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription

(2009) Johannes Schlöndorff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The podocyte and diabetes mellitus: is the podocyte the key to the origins of diabetic nephropathy?

(2009) Gaddameedi R Reddy et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The role of transient receptor potential channels in kidney disease

(2009) Titia E. Woudenberg-Vrenken et al.   Nature Reviews Nephrology

Vitamin D and Kidney Disease

(2008) W. Al-Badr et al.   Clinical Journal of the American Society of Nephrology

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

(2008) Roger Bouillon et al.   ENDOCRINE REVIEWS

The Role of Transient Receptor Potential Channels in Metabolic Syndrome

(2008) Daoyan Liu et al.   HYPERTENSION RESEARCH

Sensitizing the Slit Diaphragm with TRPC6 Ion Channels

(2008) C. C. Moller et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppression of renin–angiotensin gene expression in the kidney by paricalcitol

(2008) Michael Freundlich et al.   KIDNEY INTERNATIONAL

Proteinuria in diabetic kidney disease: A mechanistic viewpoint

(2008) J.A. Jefferson et al.   KIDNEY INTERNATIONAL

Ang-II-induced Ca2+ influx is mediated by the 1/4/5 subgroup of the transient receptor potential proteins in cultured aortic smooth muscle cells from diabetic Goto-Kakizaki rats

(2008) Jodi F. Evans et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

(2008) Christian Faul et al.   NATURE MEDICINE