Genetic markers for Clostridium difficile lineages linked to hypervirulence

Use of Modified PCR Ribotyping for Direct Detection of Clostridium difficile Ribotypes in Stool Samples

(2011) S. Janezic et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Clinical Clostridium difficile: Clonality and Pathogenicity Locus Diversity

(2011) Kate E. Dingle et al.   PLoS One

Longitudinal investigation of Clostridium difficile shedding in piglets

(2010) J. Scott Weese et al.   ANAEROBE

Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile

(2010) Gemma L Marsden et al.   BMC GENOMICS

Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

(2010) M. Merrigan et al.   JOURNAL OF BACTERIOLOGY

Relatedness of Human and Animal Clostridium difficile PCR Ribotype 078 Isolates Determined on the Basis of Multilocus Variable-Number Tandem-Repeat Analysis and Tetracycline Resistance

(2010) D. Bakker et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Mechanisms behind variation in the Clostridium difficile 16S-23S rRNA intergenic spacer region

(2010) A. Indra et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficile infection in Europe: a hospital-based survey

(2010) Martijn P Bauer et al.   LANCET

Evolutionary dynamics of Clostridium difficile over short and long time scales

(2010) M. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of Clostridium difficile in pigs and other animals in Slovenia

(2009) Jana Avbersek et al.   ANAEROBE

Flavin-dependent thymidylate synthase: A novel pathway towards thymine

(2009) Eric M. Koehn et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Typing Clostridium difficile strains based on tandem repeat sequences

(2009) N HENNING ZaiSS et al.   BMC MICROBIOLOGY

Complete Restriction of Fluoroquinolone Use to Control an Outbreak of Clostridium difficile Infection at a Community Hospital

(2009) Alexander J. Kallen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Microarray Identification of Clostridium difficile Core Components and Divergent Regions Associated with Host Origin

(2009) T. Janvilisri et al.   JOURNAL OF BACTERIOLOGY

Multilocus Sequence Typing ofClostridium difficile

(2009) David Griffiths et al.   JOURNAL OF CLINICAL MICROBIOLOGY

An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene

(2009) Eric M. Koehn et al.   NATURE

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Design, synthesis and evaluation of potent thymidylate synthase X inhibitors

(2008) F. Esra Önen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Emergence ofClostridium difficileInfection Due to a New Hypervirulent Strain, Polymerase Chain Reaction Ribotype 078

(2008) Abraham Goorhuis et al.   CLINICAL INFECTIOUS DISEASES

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

(2008) T. Akerlund et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Isolation of Clostridium difficile from food animals in Slovenia

(2008) T. Pirs et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Flavin-dependent thymidylate synthase X limits chromosomal DNA replication

(2008) F. Escartin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA