Membrane Proteases in the Bacterial Protein Secretion and Quality Control Pathway

Membrane Proteases and Aminoglycoside Antibiotic Resistance

(2011) A. Hinz et al.   JOURNAL OF BACTERIOLOGY

Initial Efforts toward the Optimization of Arylomycins for Antibiotic Activity

(2011) Tucker C. Roberts et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies

(2011) David A. Widdick et al.   MOLECULAR MICROBIOLOGY

The crystal structure of GXGD membrane protease FlaK

(2011) Jian Hu et al.   NATURE

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-liberation cleavage of signal peptides is catalyzed by the site-2 protease (S2P) in bacteria

(2011) A. Saito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes

(2010) Bianca Schrul et al.   BIOCHEMICAL JOURNAL

In Vitro Analysis of the Staphylococcus aureus Lipoteichoic Acid Synthase Enzyme Using Fluorescently Labeled Lipids

(2010) M. Karatsa-Dodgson et al.   JOURNAL OF BACTERIOLOGY

Type I Signal Peptidase and Protein Secretion in Staphylococcus epidermidis

(2010) M. E. Powers et al.   JOURNAL OF BACTERIOLOGY

Allostery Is an Intrinsic Property of the Protease Domain of DegS

(2010) Jungsan Sohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Cryomicroscopy Structure of a Membrane-anchored Mitochondrial AAA Protease

(2010) Sukyeong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conversion of a Regulatory into a Degradative Protease

(2010) Sonja Hasenbein et al.   JOURNAL OF MOLECULAR BIOLOGY

Comprehensive Characterization of Methicillin-resistantStaphylococcus aureussubsp.aureusCOL Secretome by Two-dimensional Liquid Chromatography and Mass Spectrometry

(2010) Shobha Ravipaty et al.   MOLECULAR & CELLULAR PROTEOMICS

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues

(2010) Tobias Krojer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

New insights into S2P signaling cascades: Regulation, variation, and conservation

(2010) Gu Chen et al.   PROTEIN SCIENCE

Bacillus subtilis YqjG is required for genetic competence development

(2010) Manfred J. Saller et al.   PROTEOMICS

Stress-Responsive Systems Set Specific Limits to the Overproduction of Membrane Proteins in Bacillus subtilis

(2009) J. C. Zweers et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Proteolytic processing of Escherichia coli twin-arginine signal peptides by LepB

(2009) Iris Lüke et al.   ARCHIVES OF MICROBIOLOGY

Cleavage of a Multispanning Membrane Protein by an Intramembrane Serine Protease

(2009) Elinor Erez et al.   BIOCHEMISTRY

Profiling the Substrate Specificity of Viral Protease VP4 by a FRET-Based Peptide Library Approach

(2009) Ozlem Dogan Ekici et al.   BIOCHEMISTRY

Crystallographic Analysis of Bacterial Signal Peptidase in Ternary Complex with Arylomycin A2and a β-Sultam Inhibitor

(2009) Chuanyun Luo et al.   BIOCHEMISTRY

Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase

(2009) David A. Harris et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Quality Control of Cytoplasmic Membrane Proteins in Escherichia coli

(2009) Y. Akiyama   JOURNAL OF BIOCHEMISTRY

Intramembrane Proteolysis by Signal Peptide Peptidases: A Comparative Discussion of GXGD-type Aspartyl Proteases

(2009) Regina Fluhrer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptidic small molecule activators of the stress sensor DegS

(2009) Patrick Hauske et al.   Molecular BioSystems

Sequence-Specific Intramembrane Proteolysis: Identification of a Recognition Motif in Rhomboid Substrates

(2009) Kvido Strisovsky et al.   MOLECULAR CELL

Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW

(2009) Janine Heinrich et al.   MOLECULAR MICROBIOLOGY

Signal peptides are allosteric activators of the protein translocase

(2009) Giorgos Gouridis et al.   NATURE

Rip exposed: How ectodomain shedding regulates the proteolytic processing of transmembrane substrates

(2009) D. R. Dries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage

(2009) X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines

(2009) Takashi Tatsuta et al.   RESEARCH IN MICROBIOLOGY

Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY

(2009) J. van Stelten et al.   SCIENCE

OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism

(2009) Jungsan Sohn et al.   STRUCTURE

Rhomboid Proteases and their Biological Functions

(2008) Matthew Freeman   Annual Review of Genetics

Escherichia coliSignal Peptide Peptidase A Is a Serine-Lysine Protease with a Lysine Recruited to the Nonconserved Amino-Terminal Domain in the S49 Protease Family†

(2008) Peng Wang et al.   BIOCHEMISTRY

In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells

(2008) Sinisa Urban et al.   BIOLOGICAL CHEMISTRY

Substrate specificity of γ-secretase and other intramembrane proteases

(2008) A. J. Beel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Detection of cross-links between FtsH, YidC, HflK/C suggests a linked role for these proteins in quality control upon insertion of bacterial inner membrane proteins

(2008) Edwin van Bloois et al.   FEBS LETTERS

A Pair of Circularly Permutated PDZ Domains Control RseP, the S2P Family Intramembrane Protease ofEscherichia coli

(2008) Kenji Inaba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes

(2008) Jessica C Zweers et al.   Microbial Cell Factories

The Bacillus subtilis ABC transporter EcsAB influences intramembrane proteolysis through RasP

(2008) J. Heinrich et al.   MICROBIOLOGY-SGM

Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration

(2008) Özlem Doğan Ekici et al.   PROTEIN SCIENCE

Rhomboids: 7 years of a new protease family

(2008) Matthew Freeman   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

(2008) Kunio Nakatsukasa et al.   TRAFFIC

Crystal Structure of a Bacterial Signal Peptide Peptidase

(2007) Apollos C. Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress

(2003) Hanne-Leena Hyyryläinen et al.   MOLECULAR MICROBIOLOGY