Article
Food Science & Technology
Yilmaz Ucar, Yesim Ozogul, Mustafa Durmus, Fatih Ozogul
Summary: The study found that different concentrations of nisin can inhibit the production of biogenic amines in seabass fillets, with Gram-positive foodborne pathogens being more sensitive to it. However, bacterial loads in the broth were not always correlated with biogenic amine formation.
Review
Food Science & Technology
Debapriya Mohanty, Mrutyunjay Suar, Sandeep Kumar Panda
Summary: Food spoilage bacteria and multidrug-resistant foodborne pathogens are major public health concerns, causing economic losses and posing threats to consumers. The fusion of biotechnology and nanotechnology offers potential in developing effective formulations against these microorganisms. This review critically examines the application of bacteriocins and nanomaterials in the food industry, exploring their antimicrobial activity and precision in delivery. It highlights the challenges in commercialization and provides essential information on the nanotechnological advancements and future scopes in combating food spoilage bacteria and foodborne pathogens.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Xinyi Pang, Xiaoye Song, Minjie Chen, Shuhua Tian, Zhaoxin Lu, Jing Sun, Xiangfei Li, Yingjian Lu, Hyun-Gyun Yuk
Summary: Studies have shown that LAB bacteriocins can effectively inhibit the formation of foodborne bacterial biofilms on food contact surfaces, but have difficulty in eradicating preformed biofilms. Their antibiofilm activity can be strengthened through synergistic combination with other antimicrobials, incorporation in nanoconjugates, and implementation of bioengineering.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Food Science & Technology
Manyun Yang, Xiaobo Liu, Yaguang Luo, Arne J. Pearlstein, Shilong Wang, Hayden Dillow, Kevin Reed, Zhen Jia, Arnav Sharma, Bin Zhou, Dan Pearlstein, Hengyong Yu, Boce Zhang
Summary: The system developed integrates paper chromogenic arrays (PCAs) and machine learning to automatically recognize PCA patterns on multiplexed viable pathogens with strain-level specificity. This approach has the potential to advance non-destructive pathogen detection and identification on food.
Article
Biotechnology & Applied Microbiology
Laura Nyhan, Des Field, Colin Hill, Michael Callanan, Maire Begley
Summary: This study investigated the combination of bioengineered nisin derivatives produced by Lactococcus lactis with the aim of discovering combinations with enhanced antimicrobial activity against Listeria. The results showed that certain combinations of nisin derivatives exhibited superior anti-listerial activity compared to individual derivatives or nisin A, with potential applications in food systems.
Article
Agriculture, Multidisciplinary
Aryadina M. Ribeiro, Aline D. Paiva, Alexandra M. O. Cruz, Maria C. D. Vanetti, Sukarno O. Ferreira, Hilario C. Mantovani
Summary: The study found that bovicin HC5 and nisin had bactericidal effects on A. acidoterrestris in fruit juices and reduced the D-90 degrees C values by up to 30-fold. Atomic force microscopy revealed substantial structural changes in the cellular framework of A. acidoterrestris vegetative cells treated with bovicin HC5 or nisin.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Review
Food Science & Technology
Yago Alves de Aguiar Bernardo, Denes Kaic AlvesdDo Rosario, Carlos Adam Conte-Junior
Summary: Ultrasound is a promising non-thermal technology for sterilizing milk and dairy products, but there are limitations to its industrial adoption. This review focuses on the capacity of ultrasound to inactivate pathogenic and spoilage bacteria in milk and discusses the scientific limitations of using ultrasound on an industrial scale.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Ghoson M. Daba, Faten A. Mostafa, Shireen A. A. Saleh, Waill A. Elkhateeb, Ghada Awad, Taisei Nomiyama, Takeshi Zendo, Asmaa Negm El-Dein
Summary: The Lactiplantibacillus plantarum strain GCNRC_GA15 isolated from Egyptian goat cheese showed broad antimicrobial activity with a bacteriocin (GA15) of proteineous nature. The bacteriocin GA15 exhibited heat and pH stability and its production could be increased significantly using a statistically optimized medium.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Microbiology
Longcheng Guo, Joseph Wambui, Chenhui Wang, Francis Muchaamba, Maria Victoria Fernandez-Cantos, Jaap Broos, Taurai Tasara, Oscar P. Kuipers, Roger Stephan
Summary: This study discovered a new variant of lantibiotic called cesin, which kills bacteria by inhibiting cell wall synthesis without pore formation. The lantibiotic demonstrated potent antimicrobial activity and stability, making it a potential antimicrobial compound for food and/or health applications.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Longcheng Guo, Joseph Wambui, Chenhui Wang, Francis Muchaamba, Maria Victoria Fernandez-Cantos, Jaap Broos, Taurai Tasara, Oscar P. Kuipers, Roger Stephan
Summary: Cesin, a novel variant of nisin, efficiently kills bacteria by inhibiting cell wall synthesis without pore formation. It demonstrates a broad and potent antimicrobial profile, attributed to lipid II binding and electrostatic interactions with teichoic acids. The stability tests show that cesin is highly stable under different environmental conditions.
MICROBIOLOGY SPECTRUM
(2023)
Article
Public, Environmental & Occupational Health
V. A. Leslie, Khaloud Mohammed Alarjani, Arunkumar Malaisamy, Balamuralikrishnan Balasubramanian
Summary: The study isolated a bacteriocin-producing strain Lactobacillus plantarum LA21 from the fermented food shidal, which showed antibacterial activity against pathogens, with the lowest minimum inhibitory concentration observed in Listeria monocytogenes. Additionally, molecular docking studies demonstrated relatively intense interactions between bacteriocins and their targets.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Biotechnology & Applied Microbiology
Natan De Jesus Pimentel-Filho, Stephan Fuchs, Maria Cristina Baracat-Pereira, Hilario Cuquetto Mantovani, Katharina Riedel, Maria Cristina Dantas Vanetti
Summary: This study investigates the stress response of Staphylococcus aureus to bovicin HC5 using a proteomic approach. The results show that sublethal concentrations of the bacteriocin repress protein synthesis, leading to growth reduction in the bacteria, while inducing certain proteins related to energy-efficient catabolism. This knowledge can help identify potential targets for controlling this pathogen.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Asma Ansari, Fariha Ibrahim, Muhammad Samee Haider, Afsheen Aman
Summary: The study demonstrates that Bac-IB45 produced by Lactiplantibacillus plantarum can be used as a biopreservative to effectively improve the shelf life of meat under refrigeration, with its unique N-terminal sequence aiding in inhibiting bacterial growth and preserving the texture and color of the meat.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Review
Medical Laboratory Technology
Atieh Darbandi, Arezoo Asadi, Marzieh Mahdizade Ari, Elnaz Ohadi, Malihe Talebi, Masoume Halaj Zadeh, Amir Darb Emamie, Roya Ghanavati, Maryam Kakanj
Summary: Various bacteriocins produced by lactic acid bacteria have been modified by scientists and shown to be highly effective against foodborne pathogens. The health-promoting attributes of Bifidobacterium and Lactobacillus bacteria have been characterized, and understanding their antimicrobial mechanisms is crucial. This review extensively studied the structure, classification, safety, and antibacterial properties of bacteriocins, and their impact on foodborne pathogens and antibiotic-resistant bacteria.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Article
Food Science & Technology
Salam A. Ibrahim, Raphael D. Ayivi, Tahl Zimmerman, Shahida Anusha Siddiqui, Ammar B. Altemimi, Hafize Fidan, Tuba Esatbeyoglu, Reza Vaseghi Bakhshayesh
Summary: In the face of frequent outbreaks of foodborne diseases, there is a growing emphasis on food safety and microbial control strategies. Natural antimicrobial compounds synthesized by lactic acid bacteria have shown potential in inhibiting pathogens and are widely used in the food industry.
Review
Biochemistry & Molecular Biology
Jennifer Fan, Santosh K. Mishra
Summary: Understanding the mechanisms of itch in cutaneous allergic diseases is crucial for developing new therapeutic approaches to relieve itch. Recent studies have focused on endogenous mediators released from immune/nonimmune skin cells and the receptors on sensory neurons, offering potential for more effective treatment of allergic itch.
Article
Dermatology
Santosh K. Mishra
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
Article
Education, Scientific Disciplines
Santosh Kumar Mishra, Rahul Kumar, Purushottam Ramchandra Patil, Rishiksh Gupta, Alok Mahor, Peeyush Bhardwaj
Summary: This study designed transdermal patches containing Simvastatin for managing blood lipid levels. The patches were prepared using Eudragit polymer grades ERL100 and ERS100. The best formulation was identified as F8 based on the evaluation of physicochemical characteristics and ex-vivo permeation study.
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
(2022)
Article
Metallurgy & Metallurgical Engineering
Prasenjit Biswas, Mrinal Sahu, Sanjeev Das, Santosh Mishra, Archana Mallik
Summary: The processing of Al-MMC through liquid state processing, specifically stir casting, can achieve continuous casting with uniform distribution of reinforcement particles. Researchers conducted simulation-based optimization of various parameters for the newly developed continuous casting setup, leading to successful synthesis of high-quality MMCs with minimum cast defects. This economical continuous casting process shows promise for industrial scale production of high-quality Al-MMCs.
INTERNATIONAL JOURNAL OF METALCASTING
(2022)
Review
Neurosciences
Parth Shirolkar, Santosh K. Mishra
Summary: The TRP channel superfamily responds to various stimuli, including itch. Six TRP channels are involved in itch perception, primarily in the skin and dorsal root ganglia. Mutations and activations of these channels can cause discomfort and disease.
NEUROSCIENCE LETTERS
(2022)
Review
Nanoscience & Nanotechnology
Niranjan Chatterjee, Piyush Kumar, Krishan Kumar, Santosh K. Misra
Summary: Carbon nanoparticles (CNPs) have been widely used in biology for sensing, imaging, and therapy due to their biocompatibility and unique properties. This article discusses the correlations between synthesis, characterization, and utilization of CNPs, and explores their applications in various biological activities. The insights gained from this study can lead to the development of new CNPs with improved applications and evaluation methods, ultimately benefiting human needs in the future.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2022)
Article
Neurosciences
Laura Minnema, Ankita Gupta, Santosh K. Mishra, B. Duncan X. Lascelles
Summary: This study investigates the functional role of artemin/GFR alpha 3 signaling in osteoarthritis pain and finds that anti-artemin monoclonal antibody can reverse hypersensitivity and restore limb use.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Engineering, Manufacturing
P. R. Sreeraj, Santosh Kr. Mishra, Purushottam Kumar Singh
Summary: Additive manufacturing is a promising process for complex geometries, but often fails to meet specifications due to surface quality issues and various flaws. Non-destructive evaluation is considered to be an effective method to detect and control these defects. This review discusses common defects in additive manufacturing components and the application of non-destructive evaluation methods to address them.
PROGRESS IN ADDITIVE MANUFACTURING
(2022)
Review
Biotechnology & Applied Microbiology
Ashutosh Khaswal, Neha Chaturvedi, Santosh Kumar Mishra, Priya Ranjan Kumar, Prabir Kumar Paul
Summary: The genus Geobacillus, comprising thermophilic bacteria, shows high environmental adaptability and potential for biotechnological applications. With diverse metabolic abilities, these microorganisms have promising prospects for producing biofuels, enzymes, and for bioremediation.
FOLIA MICROBIOLOGICA
(2022)
Review
Environmental Sciences
A. Ojha, S. Jaiswal, P. Thakur, S. K. Mishra
Summary: Accumulation of heavy metals increases toxic contaminants in soil and the environment, posing significant threats to ecosystems. Bioremediation, using microorganisms to lower/remove toxicity, is an important, cost-effective solution. Alternative methods like nanobioremediation, vermiremediation, and genetically modified microbes have also shown promise.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Reenu Kashyap, Kapil Singh Narayan, Shilpa Vij
Summary: This study evaluated the antimicrobial activity of bioactive peptides generated from fermented colostrum whey and found that <10 kDa peptide fractions from L. rhamnosus C25 fermented colostrum whey showed the strongest inhibition against diarrheagenic E. coli strains. The presence of diarrheagenic genes in the E. coli strains was confirmed using PCR, and the interaction between potent peptides and E. coli was observed using a scanning electron microscope.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Engineering, Electrical & Electronic
Alka Mishra, Surekha Bhusnur, Santosh Mishra
Summary: In the last 20 years, most human deaths have been caused by heart failure. ECG is an important clinical test for diagnosing dangerous cardiac electrical disturbances. Generating an artificial ECG signal that reflects the characteristics of a real ECG signal is challenging due to noise and artifacts. This paper presents a method of modeling an ECG signal and classifies it using different techniques. The tree algorithm shows the best performance in classifying abnormal and normal sinus rhythms, eliminating the need for pre-processing and traditional feature extraction techniques.
CIRCUITS SYSTEMS AND SIGNAL PROCESSING
(2023)
Article
Biotechnology & Applied Microbiology
Manish Singh Sansi, Daraksha Iram, Shilpa Vij, Suman Kapila, Sunita Meena
Summary: Goat milk proteins were partially purified and hydrolyzed to produce bioactive peptides with inhibitory activity against alpha-amylase, pancreatic lipase, angiotensin converting enzyme, and antibacterial properties against selected pathogens.
JOURNAL OF FOOD SAFETY
(2023)
Article
Biotechnology & Applied Microbiology
Upma Pal, Shilpa Vij
Summary: This study aimed to improve the ethanol tolerance of K. marxianus through adaptive evolutionary engineering. The ethanol tolerance of the parent strain was significantly increased through adaptive evolution, resulting in a significant increase in ethanol production.
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2022)
Article
Chemistry, Organic
Suryakanta Dehuri, Santosh Kumar Mishra, Bamaprasad Bag
Summary: The study successfully synthesized molecular probes with Fe(III)-selective properties by experimenting with n-alkyl substituents of varying chain lengths, demonstrating the efficient modulation of photophysical signalling parameters by these substituents.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
