Brain edema in acute liver failure: mechanisms and concepts

Sulfonylurea Receptor 1 Contributes to the Astrocyte Swelling and Brain Edema in Acute Liver Failure

(2014) A. R. Jayakumar et al.   Translational Stroke Research

Brain edema in acute liver failure: Role of neurosteroids

(2013) A.R. Jayakumar et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

(2013) Boris Görg et al.   HEPATOLOGY

Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure

(2013) Kiran K. Thumburu et al.   JOURNAL OF NEUROCHEMISTRY

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy

(2013) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROCHEMISTRY

Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering

(2013) Vinita Rangroo Thrane et al.   NATURE MEDICINE

The liver–brain axis in liver failure: neuroinflammation and encephalopathy

(2013) Roger F. Butterworth   Nature Reviews Gastroenterology & Hepatology

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Aquaporin-4 deletion in mice reduces encephalopathy and brain edema in experimental acute liver failure

(2013) Kakulavarapu V. Rama Rao et al.   NEUROBIOLOGY OF DISEASE

Blocking NMDA Receptors Delays Death in Rats with Acute Liver Failure by Dual Protective Mechanisms in Kidney and Brain

(2013) Omar Cauli et al.   NEUROMOLECULAR MEDICINE

Increased renal expression and urinary excretion of TLR4 in acute kidney injury associated with cirrhosis

(2012) Naina Shah et al.   LIVER INTERNATIONAL

Microglia contribute to ammonia-induced astrocyte swelling in culture

(2012) Kakulavarapu V. Rama Rao et al.   METABOLIC BRAIN DISEASE

Ammonia induces aquaporin-4 rearrangement in the plasma membrane of cultured astrocytes

(2012) Guillermo Bodega et al.   NEUROCHEMISTRY INTERNATIONAL

Oxidative and nitrosative stress in ammonia neurotoxicity

(2012) Marta Skowrońska et al.   NEUROCHEMISTRY INTERNATIONAL

Role of cerebral endothelial cells in the astrocyte swelling and brain edema associated with acute hepatic encephalopathy

(2012) A.R. Jayakumar et al.   NEUROSCIENCE

Prevention and treatment of hepatic encephalopathy: Focusing on gut microbiota

(2012) Matteo Garcovich   WORLD JOURNAL OF GASTROENTEROLOGY

Microglia activation in hepatic encephalopathy in rats and humans

(2011) Irina Zemtsova et al.   HEPATOLOGY

Interaction between cytokines and ammonia in the mitochondrial permeability transition in cultured astrocytes

(2011) Veronica M. Alvarez et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neuroimaging in acute liver failure

(2011) Laia Chavarria et al.   NEUROCHEMISTRY INTERNATIONAL

Ammonia-induced brain swelling and neurotoxicity in an organotypic slice model

(2011) Adam Back et al.   NEUROLOGICAL RESEARCH

Novel Treatment Targets for Cerebral Edema

(2011) Brian P. Walcott et al.   Neurotherapeutics

Brain Edema in Acute Liver Failure

(2010) Kakulavarapu V. Rama Rao et al.   AMERICAN JOURNAL OF PATHOLOGY

Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy

(2010) Regina Rodrigo et al.   GASTROENTEROLOGY

Brain Region-Selective Mechanisms Contribute to the Progression of Cerebral Alterations in Acute Liver Failure in Rats

(2010) Omar Cauli et al.   GASTROENTEROLOGY

Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy

(2010) Boris Görg et al.   HEPATOLOGY

Locomotor impairment and cerebrocortical oxidative stress in portal vein ligated rats in vivo

(2010) Jonathan Brück et al.   JOURNAL OF HEPATOLOGY

Marked potentiation of cell swelling by cytokines in ammonia-sensitized cultured astrocytes

(2010) Kakulavarapu V Rama Rao et al.   Journal of Neuroinflammation

Brain Aquaporin-4 in Experimental Acute Liver Failure

(2010) Kakulavarapu V. Rama Rao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Acute liver failure

(2010) William Bernal et al.   LANCET

Prevention and management of brain edema in patients with acute liver failure

(2010) Fin Stolze Larsen et al.   LIVER TRANSPLANTATION

Brain expression of the water channels Aquaporin-1 and -4 in mice with acute liver injury, hyperammonemia and brain edema

(2010) Martin Eefsen et al.   METABOLIC BRAIN DISEASE

NF-κB in the mechanism of brain edema in acute liver failure: Studies in transgenic mice

(2010) A.R. Jayakumar et al.   NEUROBIOLOGY OF DISEASE

Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity

(2009) Dieter Häussinger et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Direct Evidence for Central Proinflammatory Mechanisms in Rats with Experimental Acute Liver Failure: Protective Effect of Hypothermia

(2009) Wenlei Jiang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Protein kinase G is involved in ammonia-induced swelling of astrocytes

(2009) Agnieszka Konopacka et al.   JOURNAL OF NEUROCHEMISTRY

Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline

(2009) Wenlei Jiang et al.   JOURNAL OF NEUROCHEMISTRY

Inhibitors of the mitochondrial permeability transition reduce ammonia-induced cell swelling in cultured astrocytes

(2009) Pichili V. B. Reddy et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Brain volume regulation: osmolytes and aquaporin perspectives

(2009) H. Pasantes-Morales et al.   NEUROSCIENCE

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Ammonia induces RNA oxidation in cultured astrocytes and brainin vivo

(2008) Boris Görg et al.   HEPATOLOGY

Na-K-Cl Cotransporter-1 in the Mechanism of Ammonia-induced Astrocyte Swelling

(2008) Arumugam R. Jayakumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measurement of cytotoxic and interstitial components of cerebral edema in acute hepatic failure by diffusion tensor imaging

(2008) Vijan Rai et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Signaling factors in the mechanism of ammonia neurotoxicity

(2008) M. D. Norenberg et al.   METABOLIC BRAIN DISEASE

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

(2008) G.J. del Zoppo   NEUROSCIENCE