Estrogen receptor β ligands: Recent advances and biomedical applications

Synthesis and Evaluation of Estrogen Receptor β -Selective Ligands: Fluoroalkylated Indazole Estrogens

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Bromination from the Macroscopic Level to the Tracer Radiochemical Level:76Br Radiolabeling of Aromatic Compounds via Electrophilic Substitution

(2009) Dong Zhou et al.   BIOCONJUGATE CHEMISTRY

Synthesis and evaluation of aryl-substituted diarylpropionitriles, selective ligands for estrogen receptor β, as positron-emission tomographic imaging agents

(2009) Byung Seok Moon et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biphenyl C-cyclopropylalkylamides: New scaffolds for targeting estrogen receptor β

(2009) Miranda J. Sarachine et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Stimulating the GPR30 Estrogen Receptor with a Novel Tamoxifen Analogue Activates SF-1 and Promotes Endometrial Cell Proliferation

(2009) Benjamin C. Lin et al.   CANCER RESEARCH

Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta

(2009) Michael Waibel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phenethyl pyridines with non-polar internal substitutents as selective ligands for estrogen receptor beta

(2009) Michael Waibel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural Evolutions of Salicylaldoximes as Selective Agonists for Estrogen Receptor β

(2009) Filippo Minutolo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Estrogen receptor beta (ERβ) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells

(2009) Pamela A. Hershberger et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Activity and intracellular location of estrogen receptors α and β in human bronchial epithelial cells

(2009) Margarita M. Ivanova et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen receptor beta in breast cancer—Diagnostic and therapeutic implications

(2009) Johan Hartman et al.   STEROIDS

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

(2008) Eric R. Prossnitz et al.   Annual Review of Physiology

Synthesis, biological evaluation, structural–activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators

(2008) Irene Barrett et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Diarylheptanoids, new phytoestrogens from the rhizomes of Curcuma comosa: Isolation, chemical modification and estrogenic activity evaluation

(2008) Apichart Suksamrarn et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Promising core structure for nuclear receptor ligands: Design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton

(2008) Kiminori Ohta et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands

(2008) Jing Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deconstructing estradiol: Removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists

(2008) Mohammud Asim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Analysis of the effects of oestrogen receptor α (ERα)- and ERβ-selective ligands given in combination to ovariectomized rats

(2008) T Hertrampf et al.   BRITISH JOURNAL OF PHARMACOLOGY

Selective Estrogen Receptor Modulator Medicinal Chemistry At Merck. A Review

(2008) T. Blizzard   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Estrogen Receptor β Selective Ligand 5α-Androstane-3β, 17β-Diol Stimulates Spermatogonial Deoxyribonucleic Acid Synthesis in Rat Seminiferous Epitheliumin Vitro

(2008) Aida Wahlgren et al.   ENDOCRINOLOGY

Estrogen Receptor-β Agonist Diarylpropionitrile: Biological Activities ofR- andS-Enantiomers on Behavior and Hormonal Response to Stress

(2008) Michael J. Weiser et al.   ENDOCRINOLOGY

Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist

(2008) Fabrice Piu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist

(2008) Luis R. Gardell et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

CYP7B1-mediated metabolism of dehydroepiandrosterone and 5α-androstane-3β,17β-diol - potential role(s) for estrogen signaling

(2008) Hanna Pettersson et al.   FEBS Journal

The potential role of ERβ isoforms in the clinical management of breast cancer

(2008) C A Green et al.   HISTOPATHOLOGY

Different estrogen receptor β expression in distinct histologic subtypes of lung adenocarcinoma

(2008) Greta Alì et al.   HUMAN PATHOLOGY

Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)α agonist and unaffected by an ERβ antagonist

(2008) Helen L Jeanes et al.   JOURNAL OF ENDOCRINOLOGY

Synthesis and Evaluation of Estrogen Agonism of Diaryl 4,5-Dihydroisoxazoles, 3-Hydroxyketones, 3-Methoxyketones, and 1,3-Diketones: A Compound Set Forming a 4D Molecular Library

(2008) Juha T. Pulkkinen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Screening of Mono- and Di-Aryl Technetium and Rhenium Metallocarboranes. A New Class of Probes for the Estrogen Receptor

(2008) Patrick W. Causey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Monoaryl-Substituted Salicylaldoximes as Ligands for Estrogen Receptor β

(2008) Filippo Minutolo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Roles of Oestrogen Receptors α and β in Behavioural Neuroendocrinology: Beyond Yin/Yang

(2008) E. F. Rissman   JOURNAL OF NEUROENDOCRINOLOGY

Preclinical Development of a Neutral, Estrogen Receptor-Targeted, Tridentate 99mTc(I)-Estradiol-Pyridin-2-yl Hydrazine Derivative for Imaging of Breast and Endometrial Cancers

(2008) T. K. Nayak et al.   JOURNAL OF NUCLEAR MEDICINE

Estrogen receptor alpha negative breast cancer patients: Estrogen receptor beta as a therapeutic target

(2008) George P. Skliris et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Butyl 4-(butyryloxy)benzoate functions as a new selective estrogen receptor β agonist and induces GLUT4 expression in CHO-K1 cells

(2008) Zhaohu Lin et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular Structural Characteristics of Estrogen Receptor Modulators as Determinants of Estrogen Receptor Selectivity

(2008) S. Agatonovic-Kustrin et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Estrogen actions on mitochondria—Physiological and pathological implications

(2008) James W. Simpkins et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen Receptors α and β as Determinants of Gene Expression: Influence of Ligand, Dose, and Chromatin Binding

(2008) Edmund C. Chang et al.   MOLECULAR ENDOCRINOLOGY

Sterility and absence of histopathological defects in nonreproductive organs of a mouse ER -null mutant

(2008) M. C. Antal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of the membrane estrogen receptor, GPR30, with breast tumor metastasis and transactivation of the epidermal growth factor receptor

(2008) E FILARDO et al.   STEROIDS

ERβ in breast cancer—Onlooker, passive player, or active protector?

(2008) Emily M. Fox et al.   STEROIDS

Influence of Cellular ERα/ERβ Ratio on the ERα-Agonist Induced Proliferation of Human T47D Breast Cancer Cells

(2008) Ana Maria Sotoca Covaleda et al.   TOXICOLOGICAL SCIENCES

Estrogen receptor beta in the brain: From form to function

(2007) Michael J. Weiser et al.   BRAIN RESEARCH REVIEWS

Estrogenic Activities of Fatty Acids and a Sterol Isolated from Royal Jelly

(2007) Kazu-Michi Suzuki et al.   Evidence-based Complementary and Alternative Medicine

Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain

(2007) M. Morissette et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Liquiritigenin is a plant-derived highly selective estrogen receptor β agonist

(2007) Jennifer E. Mersereau et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Development of a Phase Transfer Catalyzed Asymmetric Synthesis for an Estrogen Receptor Beta Selective Agonist

(2007) Jeremy P. Scott et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The role of estrogen receptors in the control of energy and glucose homeostasis

(2007) A ROPERO et al.   STEROIDS

The role of estrogens and estrogen receptors in normal prostate growth and disease

(2007) Gail S. Prins et al.   STEROIDS

Molecular characterization of a B-ring unsaturated estrogen: Implications for conjugated equine estrogen components of Premarin

(2007) Robert W. Hsieh et al.   STEROIDS