Hybrid pharmacophore-based drug design, synthesis, and antiproliferative activity of 1,4-dihydropyridines-linked alkylating anticancer agents

Synthesis, physicochemical and kinetic studies of redox derivative of bis(2-chloroethylamine) as alkylating cytotoxic agent for brain delivery

(2015) Rajesh K. Singh et al.   Arabian Journal of Chemistry

The synthesis and biological evaluation of new DNA-directed alkylating agents, phenyl N-mustard-4-anilinoquinoline conjugates containing a urea linker

(2014) Bhavin Marvania et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of potent antitumor water-soluble phenyl N-mustard-benzenealkylamide conjugates via a bioisostere approach

(2014) Satishkumar D. Tala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis in vitro/in vivo evaluation and in silico physicochemical study of prodrug approach for brain targeting of alkylating agent

(2013) Rajesh K. Singh et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis and evaluation of aminobenzophenone derivatives containing nitrogen mustard moiety as potential central nervous system antitumor agent

(2013) Rajesh K. Singh et al.   MEDICINAL CHEMISTRY RESEARCH

Reversible redox system-based drug design, synthesis, and evaluation for targeting nitrogen mustard across brain

(2013) Rajesh K. Singh et al.   MEDICINAL CHEMISTRY RESEARCH

Cytogenetic and antineoplastic effects by newly synthesised steroidal alkylators in lymphocytic leukaemia P388 cells in vivo

(2012) C. Mourelatos et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Design and Evaluation of Primaquine-Artemisinin Hybrids as a Multistage Antimalarial Strategy

(2011) Rita Capela et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design, synthesis and antitumor evaluation of phenyl N-mustard-quinazoline conjugates

(2011) Bhavin Marvania et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bivalent bendamustine and melphalan derivatives as anticancer agents

(2011) Ana Maria Scutaru et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents

(2010) Naval Kapuriya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Anti-breast cancer activity of some novel 1,2-dihydropyridine, thiophene and thiazole derivatives

(2010) Mansour S. Al-Said et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia-activated prodrugs in cancer therapy: progress to the clinic

(2010) William A Denny   Future Oncology

Efficient Drug Lead Discovery and Optimization

(2009) William L. Jorgensen   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis, biological evaluation and molecular docking studies of amide-coupled benzoic nitrogen mustard derivatives as potential antitumor agents

(2009) Qing-Zhong Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and antitumor activity of new dihydropyridine thioglycosides and their corresponding dehydrogenated forms

(2009) Hebat-Allah S. Abbas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dihydropyridines and atypical MDR: A novel perspective of designing general reversal agents for both typical and atypical MDR

(2008) Ramin Miri et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and cytotoxic properties of new fluorodeoxyglucose-coupled chlorambucil derivatives

(2008) Bastien Reux et al.   BIOORGANIC & MEDICINAL CHEMISTRY