Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1

Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism

(2014) C. Arenaccio et al.   JOURNAL OF VIROLOGY

Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1

(2014) Claudia Arenaccio et al.   Retrovirology

Rekindled HIV infection

(2014) J. D. Siliciano et al.   SCIENCE

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases

(2013) Jung-Hyun Lee et al.   MOLECULAR CELL

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

(2013) Celsa A. Spina et al.   PLoS Pathogens

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

(2013) Susanne Eriksson et al.   PLoS Pathogens

HIV-1 genome is often defective in PBMCs and rectal tissues after long-term HAART as a result of APOBEC3 editing and correlates with the size of reservoirs

(2012) S. Fourati et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

(2012) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages

(2012) I. Kadiu et al.   JOURNAL OF IMMUNOLOGY

A Flexible Model of HIV-1 Latency Permitting Evaluation of Many Primary CD4 T-Cell Reservoirs

(2012) Kara G. Lassen et al.   PLoS One

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

(2011) Takayuki Kogure et al.   HEPATOLOGY

Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs

(2011) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling

(2010) Arthit Chairoungdua et al.   JOURNAL OF CELL BIOLOGY

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells

(2010) Alberto Bosque et al.   METHODS

HIV-1 is budded from CD4+ T lymphocytes independently of exosomes

(2010) In-Woo Park et al.   Virology Journal

The ESCRT pathway and HIV-1 budding: Figure 1

(2009) Yoshiko Usami et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

(2009) Claudia Muratori et al.   Cell Host & Microbe

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC

Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

(2008) Nancy M Archin et al.   AIDS

Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants

(2008) Réjean Cantin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism

(2008) K. Muthumani et al.   JOURNAL OF VIROLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

(2008) S. Palmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE