期刊
MATERIALS LETTERS
卷 93, 期 -, 页码 133-136出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2012.11.040
关键词
Electrospinning; Biomimetic; Polymeric composites; Collagen; Hydroxyapatite
资金
- National Science Council of Taiwan, Republic of China [NSC-100-2120-M-038-002]
In this study, a composite scaffold made of alginate (AL), chitosan (ChS), collagen (Col), and hydroxyapatite (HAp) was fabricated by electrospinning techniques. The distribution of each component of composite scaffold was revealed by confocal laser scanning microscope (CLSM) using fluorescent labeling polymers. The morphology and microstructure of the scaffold was examined using a field-emission scanning electron microscope (FE-SEM) and transmission electron microscopy (TEM). To mimic the stability of these scaffolds in physiological fluids, the degree of disintegration of collagen from these scaffolds in collagenase solution was also tested. The results showed that the composite scaffold can greatly reduce the disintegration by 35% for 10 days in collagenase solution. Therefore, this composite is expected to be a potential scaffold for bone tissue engineering applications. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据