Article
Chemistry, Physical
Imran Deen, Gurpreet Singh Selopal, Zhiming M. Wang, Federico Rosei
Summary: Coatings with bioactive and biodegradable properties were fabricated using electrophoretic deposition with composite collagen, chitosan, and copper-doped phosphate glass. Variations in the coating composition were achieved by altering the concentrations of collagen and chitosan in the solutions, as well as by depositing phosphate glass with different levels of copper dopant. The ability to deposit these polymer-phosphate glass coatings offers potential for tailored orthopaedic implants with enhanced bioactivity and reduced risk of rejection.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Arman Molaei, MardAli Yousefpour
Summary: Composite coatings of chitosan-bioglass-hydroxyapatite-halloysite nanotube were successfully produced by electrophoretic deposition, demonstrating good corrosion resistance and apatite-inducing ability in corrected simulated body fluid.
Article
Materials Science, Multidisciplinary
Ozge Varlik, Yapincak Goncu, A. Y. Nuran
Summary: Titanium diboride-chitosan composite coatings were successfully produced by electrophoretic deposition techniques. The effect of process parameters on the coatings was investigated and the suspension properties and deposition mechanism were discussed. The results showed that the coatings had a uniform and crack-free morphology, and the chitosan content significantly affected the adhesion behavior.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Review
Chemistry, Applied
Suman Kumari, Hanuma Reddy Tiyyagura, Yasir Beeran Pottathara, Kishor Kumar Sadasivuni, Deepalekshmi Ponnamma, Timothy E. L. Douglas, Andre G. Skirtach, M. K. Mohan
Summary: Metallic implants have been dominant in load-bearing applications in biomedical implant industries, while polymeric implants show great promise for tissue engineering applications. The surface properties of implants are critical for interactions with body tissues, with desired properties including biocompatibility, corrosion resistance, and antibacterial activity. Various methods such as electrophoretic deposition and sol-gel methods have been used for producing polymer coatings on implants.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Aneeqa Nawaz, Muhammad Atiq Ur Rehman
Summary: This study successfully deposited chitosan/gelatin/Ag-Mn MBGNs composite on the PEEK/BG layer, showing good antibacterial activity and biocompatibility. The addition of Mn and Ag had a significant effect on bacteria growth, but showed negligible impact on the bioactivity of the coatings. The multi-structured coatings exhibited suitable wettability and surface roughness for orthopedic applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Xin Song, Yong Hu, Huiping Qi, Zhijie Yan
Summary: In this research, a TiB2-Chitosan coating was successfully fabricated using electrophoretic deposition on the surface of 6Cr13 martensitic stainless steel. The effect of different deposition parameters on the morphology of the coating was investigated. The results showed that the TiB2-Chitosan coating significantly improved the corrosion resistance of the substrate, and the optimal deposition parameters were 40 V/60 s.
Article
Materials Science, Coatings & Films
Morteza Farrokhi-rad, Somayeh Emamalipour, Faezeh Mohammadzadeh, Younes Beygi-Khosrowshahi, Hossein Hassannejad, Ashkan Nouri
Summary: Alginate coatings were fabricated by electrophoretic deposition using alcohol-water mixtures at different ratios, with the coating deposited at 10V for 1 minute from a 60% water ethanolic solution selected as the optimum coating for promoting cell expansion and showing antibacterial activity. The EPD rate increased with water content, leading to more bubbles in the coatings, and the coated sample exhibited around 30% increase in cell expansion after 7 days compared to the blank sample. Additionally, the coated sample demonstrated antibacterial activity against Bacillus bacteria.
SURFACE ENGINEERING
(2021)
Article
Polymer Science
Arash Ghalayani Esfahani, Maria Sartori, Chiara Bregoli, Jacopo Fiocchi, Carlo Alberto Biffi, Ausonio Tuissi, Gianluca Giavaresi, Alessandro Presentato, Rosa Alduina, Angela De Luca, Alessia Cabrini, Cristina De Capitani, Milena Fini, Emanuele Gruppioni, Marino Lavorgna, Alfredo Ronca
Summary: Prosthetic reconstruction can provide functional and aesthetic benefits to individuals with hand and finger injuries. This study developed a new silver-doped chitosan coating as a potential solution for infection therapy. The coatings exhibited impressive biological and physical properties.
Article
Materials Science, Coatings & Films
Muhammad Asim Akhtar, Camilla E. Mariotti, Bice Conti, Aldo R. Boccaccini
Summary: In this study, chitosan-bioactive glass-ferulic acid composite coatings were successfully fabricated using AC-EPD technique. The coatings exhibited good biocompatibility and antibacterial properties, enhancing the viability of MG-63 human osteoblast-like cells. Furthermore, the coatings formed a hydroxyapatite surface layer after incubation in simulated body fluid.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Yang Hu, Yunan Qing, Yongjie Wei, Dongdong Li
Summary: The functional composite coating prepared on TC4 substrate by MAO and EPD technologies exhibited good adhesion and corrosion resistance, as well as significant bactericidal efficiency exceeding 98%.
Article
Materials Science, Multidisciplinary
Sandeep Singh, Gurpreet Singh, Niraj Bala
Summary: The study focused on electrophoretic deposition of hydroxyapatite, bioglass, and iron oxide nanoparticles nanocomposite coating into chitosan matrix on AZ91 Mg alloy. The nanocomposite coatings exhibited a porous spherical structure, with the hydroxyapatite-bioglass-1% iron oxide coating showing the highest corrosion resistance. Hemocompatibility tests indicated a hemolysis ratio < 5% and no detrimental effects on erythrocytes, suggesting the potential of this coating for degradable implant applications.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Materials Science, Coatings & Films
Sandeep Singh, Gurpreet Singh, Niraj Bala
Summary: The study fabricated a composite coating of CS-HA-BG-Fe3O4 with bioactivity, high corrosion resistance, and excellent cell proliferation, suitable for biomedical applications.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Applied
Mengna Tian, Zhangfei Lin, Wenyan Tang, Wenpeng Wu, Li Wang, Jinglai Zhang
Summary: Electrophoretic deposition was used to prepare bioactive glass-chitosan coating loaded with tetracycline on AZ31B magnesium alloy. The coating exhibited improved corrosion resistance, antibacterial activity, and osteogenic induction properties. It has potential for application in medical devices and bone implant materials.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Chemistry, Applied
Ehsan Vafa, Reza Bazargan-Lari, Mohammad Ebrahim Bahrololoom
Summary: In this study, a polyvinyl alcohol reinforced natural chitosan/bioactive glass composite coating was prepared on 316L stainless steel by electrophoretic deposition process. The 25% PVA concentration in the composite coating showed increased corrosion resistance and bio-stability compared to 15% and 20% PVA concentrations, with better bioactivity and hydroxyapatite forming ability in vitro observed with 20% PVA concentration.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Chemistry, Medicinal
Ewelina Pabjanczyk-Wlazlo, Nina Tarzynska, Anna Bednarowicz, Adam K. Puszkarz, Grzegorz Szparaga
Summary: Hyaluronate and alginate are non-toxic and biocompatible polymers used for surface modification, but their application on textiles is limited. This study analyzed the effects of EPD process parameters and fibrous carrier structures on the characteristics of deposited layers, providing a basis for further development of fibrous materials in medical applications.
Review
Materials Science, Multidisciplinary
Farnaz Ghorbani, Theresa Reiter, Liliana Liverani, Dirk W. Schubert, Aldo R. Boccaccini, Judith A. Roether
Summary: Electrospinning is a promising method for designing fibrous tissue engineering scaffolds for hard and soft tissues. Incorporating bioactive cues, such as bioactive glass (BG), into electrospun biopolymer fibers has shown potential in improving fiber properties and enhancing biological performance. This article provides a comprehensive overview of BG-containing electrospun polymer composite fibers and discusses their effects on mechanical properties, biological response, and applications in bone regeneration, wound healing, and drug delivery. The study highlights essential aspects for future translational research in tissue engineering using BG-polymer composite fibers.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Giovanni Falcone, Sonja Kuth, Aldo R. Boccaccini, Rita P. Aquino, Tiziana Esposito, Paola Russo
Summary: To fully utilize the potential of 3D printing, particularly in the case of semisolid extrusion (SSE), the technological challenges need to be addressed. This study focuses on investigating the physicochemical properties of natural polymers, specifically alginate hydrogel, for 3D printing tablets that are easy to swallow. By adding sorbitol as a plasticizer, the aim is to improve the swallowability of the tablets. Different concentrations of sorbitol solution are evaluated to determine the best composition in terms of printing and technological properties. The results highlight a predictable relationship between the amount of sorbitol loaded and the residual mass of the final platforms.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
F. Maciag, T. Moskalewicz, K. Cholewa-Kowalska, Z. Hadzhieva, M. Dziadek, A. Lukaszczyk, A. R. Boccaccini
Summary: The objective of this study was to develop cathodic electrophoretic deposition (EPD) to obtain composite coatings of mesoporous sol-gel glass (MSGG) particles embedded in a zein matrix on Ti-13Nb-13Zr substrates. The EPD process successfully produced uniform coatings with open porosity and good adhesion to the substrates. The coated substrates exhibited improved resistance to electrochemical corrosion, as well as moderate hydrophilicity and roughness. The composite coatings also showed enhanced antibacterial properties and the ability to form hydroxyapatite.
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
(2023)
Review
Materials Science, Multidisciplinary
Annabel Braem, Nur Hidayatul Nazirah Kamarudin, Nitu Bhaskar, Zoya Hadzhieva, Andrea Mele, Jeremy Soulie, Denver P. Linklater, Linda Bonilla-Gameros, Aldo R. Boccaccini, Ipsita Roy, Christophe Drouet, Elena P. Ivanova, Diego Mantovani, Bikramjit Basu
Summary: Peri-implant infection is a significant challenge in the clinical field. Researchers are developing biomaterial and bioengineering-based antimicrobial strategies to tackle this issue. However, the development of these approaches is hindered by challenges like biocompatibility concerns, reduced antimicrobial effectiveness, long-term stability issues, and antibiotic resistance development. This review provides insights into current state-of-the-art biomaterial-based antimicrobial approaches and highlights the importance of translational research strategies and regulatory frameworks for clinical implementation. The integration of computational tools and experimental databases using artificial intelligence (AI) is proposed as a vision to accelerate the development of next-generation biomaterial-based antimicrobial strategies.
INTERNATIONAL MATERIALS REVIEWS
(2023)
Article
Materials Science, Biomaterials
Irem Unalan, Stefan Schruefer, Dirk W. Schubert, Aldo R. Boccaccini
Summary: This study aimed to develop 3D-printed hydrogels as multifunctional wound dressings containing phytotherapeutic agents. Results showed that blending xanthan gum (XAN) overcame the challenges associated with sodium alginate (ALG) in terms of printability and shape fidelity. Clove essential oil (CLV) was successfully incorporated into the 3D-printed hydrogels, exhibiting long-term release and enhanced antioxidant and antibacterial activity. Additionally, CLV showed potential anti-inflammatory effects and had no toxic effect on NHDF cells. Overall, this study highlights the potential benefits of incorporating natural phytotherapeutics into 3D-printed hydrogels for wound healing.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Oncology
Joerg Fellenberg, Sarina Losch, Max R. Marinescu, Birgit Frey, Burkhard Lehner, Marcela Arango-Ospina, Zoya Hadzhieva, Aldo R. Boccaccini, Fabian Westhauser
Summary: The cytotoxic effects of bioactive glasses (BGs) on giant cell tumor (GCTB) cell lines were observed in vitro, and a significant reduction in tumor formation and growth was seen in the chicken chorioallantoic membrane (CAM) assay. These findings suggest that BGs could be potential candidates for the treatment of GCTBs.
Article
Pharmacology & Pharmacy
Mirna L. Sanchez, Hugo Valdez, Micaela Conde, Pamela Viana-Mendieta, Aldo R. Boccaccini
Summary: This article discusses the development of biomaterial platforms using functional hydrogels for delivering reagents of interest in the field of biomedicine. In situ dosing of therapeutic components for dermatological injuries, such as diabetic foot ulcers, is a novel strategy to improve wound healing. Hydrogels have shown advantages over other therapies in terms of comfort and their compatibility with tissues. The paper also proposes a new approach to wound care by modulating macrophage polarization using advanced biomaterials.
Editorial Material
Biotechnology & Applied Microbiology
Farnaz Ghorbani, Behafarid Ghalandari, Aldo R. Boccaccini, Derek H. Rosenzweig
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Thomas Gruhn, Camilo Ortiz Monsalve, Claudia Mueller, Susanne Heid, Aldo R. Boccaccini, Sahar Salehi
Summary: In this study, the dynamics of anisotropic fillers in fibrous structures with hydrogel-based matrices were analyzed using computational simulations. Microfabricated rods were used as anisotropic fillers in the fabrication of composite filaments and their orientation in the fibers was evaluated experimentally. The results showed that the fillers were not well aligned during the extrusion process, leading to a random distribution in the fibers.
BIOENGINEERING-BASEL
(2023)
Article
Electrochemistry
F. Maciag, T. Moskalewicz, K. Cholewa-Kowalska, Z. Hadzhieva, M. Dziadek, B. Dubiel, A. Lukaszczyk, A. R. Boccaccini
Summary: Cu- and Mg-doped mesoporous sol-gel bioactive glasses were developed and their microstructure was investigated. The electrophoretic deposition conditions for composite coatings on Ti-13Nb-13Zr substrates were determined. The coated alloy showed enhanced resistance to electrochemical corrosion and improved antibacterial properties compared to pure zein.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Irem Unalan, Ilenia Occhipinti, Marta Miola, Enrica Verne, Aldo R. Boccaccini
Summary: This study used polycaprolactone (PCL) and melt electrowriting (MEW) technique to fabricate scaffolds coated with superparamagnetic iron oxide nanoparticles (SPIONs) and silica-coated-SPIONs (Si-SPIONs). The hydrophilicity of the scaffolds was improved by alkaline treatment. The scaffolds showed good biocompatibility. The alkaline-treated scaffolds and SPIONs/Si-SPIONs-coated scaffolds exhibited higher pre-osteoblastic cell adhesion and proliferation efficiency. All samples were able to generate heat when subjected to an alternating magnetic field, useful for hyperthermia treatment.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Jonas Hazur, Jonas Roeder, Jonas Czwalinna, Dirk W. W. Schubert, Aldo R. R. Boccaccini
Summary: The main challenge in extrusion-based bioprinting is to develop inks with multiple characteristics before, during, and after printing. Hydrogel microparticles (HMPs) are proposed to produce internally pre-crosslinked inks, which effectively improve printability. Rheological measurements reveal the increase in yield stress and viscosity, as well as the reduction in loss angle, after HMP pre-crosslinking. Additionally, pre-crosslinking significantly alters the hydrogel's internal microstructure and NIH/3T3 cells proliferate in HMP pre-crosslinked bioinks.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Catalina Adler, Mahshid Monavari, Gustavo A. Abraham, Aldo R. Boccaccini, Farnaz Ghorbani
Summary: This study synthesized electroconductive silane-modified gelatin-poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) scaffolds to simulate the chemistry and piezoelectricity of bone. The scaffolds were functionalized with polydopamine (PDA) inspired by mussels to enhance hydrophilicity, cell interaction, and biomineralization. Analysis showed that the PDA-coated scaffolds had improved electrical resistance, hydrophilicity, compressive strength, modulus, and biomineralization capability. The scaffolds also promoted the viability, adhesion, proliferation, alkaline phosphatase expression, and HA deposition of MG-63 cells, indicating their potential for bone regeneration.
Article
Engineering, Biomedical
Hazel O. Simila, Ana M. Beltran, Aldo R. Boccaccini
Summary: This study investigated the antimicrobial and mechanical properties of dental floss coated with chitosan or chitosan + mesoporous bioactive glass nanoparticles. The coatings showed significant ability to inhibit bacterial growth after 24 hours, although the impact was minimal at 3 hours. Furthermore, the addition of these layers improved the tensile strength of the floss, making it more effective for cleaning between teeth. Enhanced investigations of these composites are therefore proposed due to their potential in promoting oral health.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2023)
Article
Chemistry, Physical
Soledad Stagnoli, Cintia Garro, Ozlem Ertekin, Susanne Heid, Stefan Seyferth, Gaston Soria, N. Mariano Correa, Aldo Leal-Egana, Aldo R. Boccaccini
Summary: This study developed a system for delivering water-insoluble drugs, which can efficiently load drugs and increase the likelihood of drug uptake by cancer cells instead of healthy cells. The system also demonstrates high efficiency and stability during topical application, and it is less invasive compared to alternative methods.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.
