Article
Pharmacology & Pharmacy
Pamela Soledad Bustos, Melisa de los Angeles Quinteros, Diego Sebastian Gomez, Maria Gabriela Ortega, Paulina Laura Paez, Natalia Lorena Guinazu
Summary: This study investigated the effects of silver bionanoparticles (AgNPs) on human trophoblasts, revealing changes in cell morphology, reduced cell viability, alterations in redox balance with increased ROS and RNS levels, as well as protein oxidation and genotoxic damage. The cytotoxicity of AgNPs was found to be mediated by nitric oxide and glutathione pathways, highlighting differences in toxicity mechanisms between eukaryotic and prokaryotic cells and emphasizing the importance of toxicity evaluation for the safety of AgNPs with pharmaceutical applications.
Article
Engineering, Environmental
Mislav Mustapic, Zvonko Glumac, Marija Heffer, Milorad Zjalic, Ivan Proloscic, Mostafa Masud, Senka Blazetic, Ana Vukovic, Motasim Billah, Aslam Khan, Suzana Segota, Md Shahriar Al Hossain
Summary: The research developed a drug delivery system based on combined AC/DC magnetic fields, using a magnetic syringe device to stimulate drug release and reduce cell viability, with the removal of drug carriers to prevent potential side effects in the patient's body.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Physical
Mostafa F. Al-Hakkani, Gamal A. Gouda, Sedky H. A. Hassan, Adham M. Nagiub
Summary: Ferric oxide Alpha Hematite nanoparticles (alpha-HNPs) synthesized using Echinacea purpurea liquid extract demonstrated excellent physicochemical properties and showed antibacterial and anti-inflammatory activities, as well as significant cytotoxic effects on various cell lines.
SURFACES AND INTERFACES
(2021)
Article
Environmental Sciences
Ka Young Kim, Shin Myung Kim, Jee Young Kim, Yoon-E Choi
Summary: Understanding the cytotoxic mechanisms of environmental contaminants, such as graphene oxide (GO), is crucial for assessing their environmental impacts and developing pollution control guidelines. This study found that the cytotoxicity of GO on microalgae is influenced by its size and the trophic mode of the microalgae. The major cytotoxic mechanism of GO is related to the inhibition of photosynthetic activity, and nano-sized GO is more toxic than micro-sized GO. Nano-sized GO enters the cells through endocytic activity/piercing, while micro-sized GO attaches to the cell surface. Both nano-sized and micro-sized GO induce oxidative stress in the cells, with higher oxidative stress parameters observed in cells exposed to nano-sized GO.
Article
Nanoscience & Nanotechnology
Liping Zou, Guiping Cheng, Chengcheng Xu, Heyu Liu, Yingying Wang, Nianyu Li, Xiaorong Fan, Changhong Zhu, Wei Xia
Summary: CuNPs induce oxidative stress in human ovarian granulosa cells, possibly through the MAPK14-Nrf2 signaling pathway to induce HO-1 expression, but HO-1 can protect cells from oxidative stress induced by CuNPs.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Biophysics
Masoud Eskandani, Morteza Eskandani, Somayeh Vandghanooni, Bahman Navidshad, Farzad Mirzaei Aghjehgheshlagh, Ali Nobakht
Summary: This study successfully enhanced the bioavailability of L-carnitine (LC) using solid lipid nanoparticles (SLNs) as carriers and demonstrated the protective effects of LC-SLNs against intracellular oxidative stress damages.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Rafal Kretowski, Agata Jablonska-Trypuc, Marzanna Cechowska-Pasko
Summary: This study evaluated the anti-cancer effect and mechanism of action of SiNPs in breast cancer cell lines. The results showed that 5-15 nm SiNPs induced dose-dependent cytotoxicity in MDA-MB-231 and ZR-75-1 cells, and also induced apoptosis through decreasing mitochondrial membrane potential and increasing the activity of caspase-9 and caspase-3. Additionally, these nanoparticles caused an increase in selected oxidative stress parameters in breast cancer cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Tamanna Roy, Surya Kanta Dey, Ananya Pradhan, Angsuman Das Chaudhuri, Malay Dolai, Santi M. Mandal, Sujata Maiti Choudhury
Summary: In this research, eco-friendly and cost-effective silver nanoparticles were synthesized and characterized. These nanoparticles showed significant antioxidant and antineoplastic effects both in vitro and in vivo. The nanoparticles induced cytotoxicity and oxidative stress in cancer cells, while enhancing the antioxidant status of the host. These findings suggest that these nanoparticles have potential applications in T-cell lymphoma therapy.
Article
Multidisciplinary Sciences
Natalia Janik-Olchawa, Agnieszka Drozdz, Damian Ryszawy, Maciej Pudelek, Karolina Planeta, Zuzanna Setkowicz, Maciej Sniegocki, Magdalena Wytrwal-Sarna, Marta Gajewska, Joanna Chwiej
Summary: This study compared the impact of PEG-coated magnetite nanoparticles with different core sizes on six selected cell lines. It was found that exposure to these nanoparticles led to decreased cell viability, which was dependent on exposure time rather than core diameter. The nanoparticles not only increased the proliferation rate of macrophages but also stimulated tumor cell divisions. Additionally, the smallest nanoparticles mainly induced an increase in ROS levels in cells.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Koigoora Srikanth, Venkatramaiah Nutalapati
Summary: The study found that exposure to copper ferrite nanoparticles led to a decrease in cell survival, increased oxidative stress, decreased antioxidant capacity, and morphological changes in CCO cells. The research also delves into the detailed mechanism of toxicity of CuFe2O4NPs in other model cell lines to assess the risk to inhabiting organisms.
Article
Chemistry, Multidisciplinary
Songjing Zhong, Zeyu Zhang, Yunchao Zhao, Shaobo Wang, Quanhong Hu, Linlin Li
Summary: Researchers have fabricated bismuth nanoclusters as nanozymes that exhibit both catalytic and photothermal therapy effects. These nanozymes can generate toxic substances and deplete antioxidants in the tumor microenvironment, leading to remarkable antitumor effects.
Article
Chemistry, Multidisciplinary
Songjing Zhong, Zeyu Zhang, Yunchao Zhao, Shaobo Wang, Quanhong Hu, Linlin Li
Summary: We have designed a highly efficient bismuth nanocluster supported on nitrogen-doped porous carbon as a nanozyme (Bi-NC) for cancer therapy. At the same time, Bi-NC shows good photothermal conversion performance to generate heat for strengthening the therapy.
Article
Polymer Science
Vitaly K. Vorobiov, Alexander N. Bugrov, Igor A. Kasatkin, Sergey A. Bolshakov, Maria P. Sokolova, Nikolay N. Smirnov, Michael A. Smirnov
Summary: A hybrid hydrogel based on polypyrrole and hydrothermally prepared alpha-Fe2O3 nanoparticles was synthesized, showing increased specific capacitance and good cycling stability. The uniform distribution of alpha-Fe2O3 particles in the hybrid hydrogel had a significant impact on its structure and electrochemical performance.
Article
Chemistry, Physical
Mostafa A. Al-Hakkani, Gamal M. Gouda, Sedky H. A. Hassan, Mahmoud M. A. Mohamed, Adham M. Nagiub
Summary: The current study evaluates the adsorption performance of biofabricated α-HNPs for the removal of Cfx drug from pharmaceutical wastewater. The results show that α-HNPs have strong adsorption capacity for the drug and exhibits inhibitory effects on various bacteria and cancer cells, indicating their potential therapeutic value.
SURFACES AND INTERFACES
(2022)
Article
Multidisciplinary Sciences
Suresh Sagadevan, Ramesh Poonchi Sivasankaran, J. Anita Lett, Is Fatimah, Getu Kassegn Weldegebrieal, Estelle Leonard, Minh-Vien Le, Tetsuo Soga
Summary: The synthesis and characterization of hematite (& alpha;-Fe2O3) nanoparticles (NPs) were conducted, and their photocatalytic properties were studied. The α-Fe2O3 NPs were found to have a rhombohedral phase confirmed by XRD, and FT-IR was used to analyze functional groups on the catalyst surface. The bandgap energy was determined to be 2.25 eV using UV-Vis DRS, and SEM images showed a spherical morphology. The α-Fe2O3 NPs exhibited oxidation and reduction properties as analyzed by CV. Under natural sunlight, the degradation efficiency of methylene blue (MB) dye using the α-Fe2O3 NPs reached 33% in 2 hours, with a pseudo-first-order rate constant of 0.0033 min(-1).
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.