Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring
出版年份 2015 全文链接
标题
Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring
作者
关键词
Paternal age, Infertility, Semen parameters, Reproduction, Genetics, Sperm DNA damage, Telomere length, Aneuploidy, Epigenetics, Offspring, Assisted reproductive techniques
出版物
Reproductive Biology and Endocrinology
Volume 13, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-04-18
DOI
10.1186/s12958-015-0028-x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Consistent age-dependent declines in human semen quality: A systematic review and meta-analysis
- (2015) Sheri L. Johnson et al. AGEING RESEARCH REVIEWS
- Mitochondrial permeability transition increases reactive oxygen species production and induces DNA fragmentation in human spermatozoa
- (2015) F. Treulen et al. HUMAN REPRODUCTION
- Oxidative stress and male reproductive health
- (2014) RobertJ Aitken et al. ASIAN JOURNAL OF ANDROLOGY
- Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing
- (2014) Francesca Rossiello et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis
- (2014) Jing Zhao et al. FERTILITY AND STERILITY
- Development of a high-resolution Y-chromosome microarray for improved male infertility diagnosis
- (2014) Ryan K.C. Yuen et al. FERTILITY AND STERILITY
- MicroRNAs and spermatogenesis
- (2014) Noora Kotaja FERTILITY AND STERILITY
- Paternal influence of sperm DNA integrity on early embryonic development
- (2014) L. Simon et al. HUMAN REPRODUCTION
- How to overcome male infertility after 40: Influence of paternal age on fertility
- (2014) Stephanie Belloc et al. MATURITAS
- Infertile men older than 40 years are at higher risk of sperm DNA damage
- (2014) Saad Alshahrani et al. Reproductive Biology and Endocrinology
- Assessing sperm chromatin and DNA damage: clinical importance and development of standards
- (2014) A. Zini et al. Andrology
- Paternal Age at Childbearing and Offspring Psychiatric and Academic Morbidity
- (2014) Brian M. D’Onofrio et al. JAMA Psychiatry
- A Comprehensive Assessment of Parental Age and Psychiatric Disorders
- (2014) John J. McGrath et al. JAMA Psychiatry
- Grand-paternal age and the development of autism-like symptoms in mice progeny
- (2014) S Sampino et al. Translational Psychiatry
- MicroRNAs as Mediators of the Ageing Process
- (2014) Lorna Harries Genes
- Effects of age on male fertility
- (2013) Michael Zitzmann BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- The Paternal Age Effect: A Multifaceted Phenomenon
- (2013) Jamila R. Momand et al. BIOLOGY OF REPRODUCTION
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
- (2013) Linda Broer et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Aging sperm negatively impacts in vivo and in vitro reproduction: a longitudinal murine study
- (2013) Mandy G. Katz-Jaffe et al. FERTILITY AND STERILITY
- Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels
- (2013) Timothy G. Jenkins et al. FERTILITY AND STERILITY
- Age thresholds for changes in semen parameters in men
- (2013) Bronte A. Stone et al. FERTILITY AND STERILITY
- The clinical utility of sperm DNA integrity testing: a guideline
- (2013) FERTILITY AND STERILITY
- Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: assessment of genetic variants and assisted reproductive technology outcome
- (2013) Debbie Montjean et al. FERTILITY AND STERILITY
- Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress
- (2013) T.B. Smith et al. FREE RADICAL BIOLOGY AND MEDICINE
- microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy
- (2013) Clémence Belleannée et al. HUMAN REPRODUCTION
- In young men sperm telomere length is related to sperm number and parental age
- (2013) A. Ferlin et al. HUMAN REPRODUCTION
- Leukocyte Telomere Length and the Father's Age Enigma: Implications for Population Health and for Life Course
- (2013) A. Aviv et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Defining “Term” Pregnancy
- (2013) Catherine Y. Spong JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- High prevalence of isolated sperm DNA damage in infertile men with advanced paternal age
- (2013) Mausumi Das et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- The future for genetic studies in reproduction
- (2013) G. W. Montgomery et al. MOLECULAR HUMAN REPRODUCTION
- The source and significance of DNA damage in human spermatozoa; a commentary on diagnostic strategies and straw man fallacies
- (2013) R. J. Aitken et al. MOLECULAR HUMAN REPRODUCTION
- Male-driven de novo mutations in haploid germ cells
- (2013) M.-C. Gregoire et al. MOLECULAR HUMAN REPRODUCTION
- Dicer Expression Exhibits a Tissue-Specific Diurnal Pattern That Is Lost during Aging and in Diabetes
- (2013) Yuanqing Yan et al. PLoS One
- Age, the environment and our reproductive future: bonking baby boomers and the future of sex
- (2013) R John Aitken REPRODUCTION
- Telomeres shorten at equivalent rates in somatic tissues of adults
- (2013) Lily Daniali et al. Nature Communications
- Autism Risk Across Generations
- (2013) Emma M. Frans et al. JAMA Psychiatry
- The role of DNA damage and repair in aging through the prism of Koch-like criteria
- (2012) Alexey A. Moskalev et al. AGEING RESEARCH REVIEWS
- Analysis of sperm telomere length in men with idiopathic infertility
- (2012) J. Thilagavathi et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Perinatal characteristics and retinoblastoma
- (2012) Julia E. Heck et al. CANCER CAUSES & CONTROL
- Paternal age at birth is associated with offspring leukocyte telomere length in the nurses' health study
- (2012) J. Prescott et al. HUMAN REPRODUCTION
- The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
- (2012) L. Robinson et al. HUMAN REPRODUCTION
- Epigenetics and its role in male infertility
- (2012) Rima Dada et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans
- (2012) K. I. Aston et al. MOLECULAR HUMAN REPRODUCTION
- Fathers bequeath more mutations as they age
- (2012) Ewen Callaway NATURE
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- Rate of de novo mutations and the importance of father’s age to disease risk
- (2012) Augustine Kong et al. NATURE
- Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
- (2012) Brian J. O’Roak et al. NATURE
- Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
- (2012) Marzia Fumagalli et al. NATURE CELL BIOLOGY
- Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants
- (2012) D. T. A. Eisenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Clinical Utility of the Protamine 1/Protamine 2 Ratio in Sperm
- (2012) Laszlo Nanassy et al. PROTEIN AND PEPTIDE LETTERS
- Advanced paternal age increases the risk of schizophrenia and obsessive–compulsive disorder in a Chinese Han population
- (2012) Yuejing Wu et al. PSYCHIATRY RESEARCH
- A comparison of ejaculated and testicular spermatozoa aneuploidy rates in patients with high sperm DNA damage
- (2012) Sergey I. Moskovtsev et al. Systems Biology in Reproductive Medicine
- Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data
- (2012) Joy E Lawn et al. BMC Pregnancy and Childbirth
- Study of aneuploidy rate and sperm DNA fragmentation in large-headed, multiple-tailed spermatozoa
- (2011) S. Brahem et al. ANDROLOGIA
- Correlation between male age, WHO sperm parameters, DNA fragmentation, chromatin packaging and outcome in assisted reproduction technology
- (2011) M. Nijs et al. ANDROLOGIA
- Turning point of age for semen quality: a population-based study in Chinese men
- (2011) Qian-Xi Zhu et al. FERTILITY AND STERILITY
- The effects of male aging on semen quality, sperm DNA fragmentation and chromosomal abnormalities in an infertile population
- (2011) Sonia Brahem et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics
- (2011) B. Demir et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Leukocyte telomere length, breast cancer risk in the offspring: The relations with father's age at birth
- (2011) Konstantin G. Arbeev et al. MECHANISMS OF AGEING AND DEVELOPMENT
- A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder
- (2011) Z Kaminsky et al. MOLECULAR PSYCHIATRY
- De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
- (2011) G Kirov et al. MOLECULAR PSYCHIATRY
- Paternal age and psychiatric disorders: Findings from a Dutch population registry
- (2011) Jacobine E. Buizer-Voskamp et al. SCHIZOPHRENIA RESEARCH
- Advanced paternal and grandpaternal age and schizophrenia: A three-generation perspective
- (2011) Emma M. Frans et al. SCHIZOPHRENIA RESEARCH
- Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males
- (2011) N. El Hajj et al. Sexual Development
- Are sperm chromatin and DNA defects relevant in the clinic?
- (2011) Armand Zini Systems Biology in Reproductive Medicine
- Analysis of Sperm Aneuploidies and DNA Fragmentation in Patients With Globozoospermia or With Abnormal Acrosomes
- (2011) Sonia Brahem et al. UROLOGY
- Critical Appraisal of World Health Organization's New Reference Values for Human Semen Characteristics and Effect on Diagnosis and Treatment of Subfertile Men
- (2011) Sandro C. Esteves et al. UROLOGY
- Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here
- (2011) Evdokia Anagnostou et al. Molecular Autism
- Comparative profiling of genes and miRNAs expressed in the newborn, young adult, and aged human epididymides
- (2010) Jinsong Zhang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Impact of cellular senescence signature on ageing research
- (2010) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- Human Male Infertility Associated with Mutations in NR5A1 Encoding Steroidogenic Factor 1
- (2010) Anu Bashamboo et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Paternal Age at Birth of First Child and Risk of Schizophrenia
- (2010) Liselotte Petersen et al. AMERICAN JOURNAL OF PSYCHIATRY
- Advanced age increases chromosome structural abnormalities in human spermatozoa
- (2010) Cristina Templado et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Assessing loss of imprint methylation in sperm from subfertile men using novel methylation polymerase chain reaction Luminex analysis
- (2010) Akiko Sato et al. FERTILITY AND STERILITY
- The effect of paternal age on assisted reproduction outcome
- (2010) Lena Dain et al. FERTILITY AND STERILITY
- Epigenetics and the origins of paternal effects
- (2010) James P. Curley et al. HORMONES AND BEHAVIOR
- State of the Art for Genetic Testing of Infertile Men
- (2010) Robert I. McLachlan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications
- (2010) Riccardo Dolcetti et al. MEDICINAL RESEARCH REVIEWS
- Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies
- (2010) C M Hultman et al. MOLECULAR PSYCHIATRY
- Influence of paternal age on assisted reproduction outcome
- (2010) Jose Bellver et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Effect of maternal and paternal age on pregnancy and miscarriage rates after intrauterine insemination
- (2010) Stéphanie Belloc et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Meta-analysis of Paternal Age and Schizophrenia Risk in Male Versus Female Offspring
- (2010) Brian Miller et al. SCHIZOPHRENIA BULLETIN
- TUNEL as a Test for Sperm DNA Damage in the Evaluation of Male Infertility
- (2010) Rakesh K. Sharma et al. UROLOGY
- Envejecimiento y calidad seminal: un análisis de 9.168 casos en Córdoba, Argentina
- (2010) Rosa Isabel Molina et al. ARCHIVOS ESPANOLES DE UROLOGIA
- DNA Damage in Human Spermatozoa Is Highly Correlated with the Efficiency of Chromatin Remodeling and the Formation of 8-Hydroxy-2′-Deoxyguanosine, a Marker of Oxidative Stress1
- (2009) Geoffry N. De Iuliis et al. BIOLOGY OF REPRODUCTION
- Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men
- (2009) Céline Chalas Boissonnas et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Large-scale parent–child comparison confirms a strong paternal influence on telomere length
- (2009) Katarina Nordfjäll et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Paternal age and assisted reproductive technology outcome in ovum recipients
- (2009) Martha Luna et al. FERTILITY AND STERILITY
- Negative influence of paternal age on clinical intracytoplasmic sperm injection cycle outcomes in oligozoospermic patients
- (2009) Renata Cristina Ferreira et al. FERTILITY AND STERILITY
- Semen quality and age-specific changes: a study between two decades on 3,729 male partners of couples with normal sperm count and attending an andrology laboratory for infertility-related problems in an Indian city
- (2009) Dyutiman Mukhopadhyay et al. FERTILITY AND STERILITY
- Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing
- (2009) Daniel Summerer GENOMICS
- Sperm chromatin structure assay as an independent predictor of fertility in vivo: a case-control study
- (2009) Aleksander Giwercman et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Are Tests of Sperm DNA Damage Clinically Useful? Pros and Cons
- (2009) A. Zini et al. JOURNAL OF ANDROLOGY
- Paternal and maternal ages at conception and risk of bipolar affective disorder in their offspring
- (2009) P. R. Menezes et al. PSYCHOLOGICAL MEDICINE
- Paternal age as a risk factor for schizophrenia: How important is it?
- (2009) E. Fuller Torrey et al. SCHIZOPHRENIA RESEARCH
- Sperm DNA Damage: Correlation to Severity of Semen Abnormalities
- (2009) Sergey I. Moskovtsev et al. UROLOGY
- The Ups and Downs of Mutation Frequencies during Aging Can Account for the Apert Syndrome Paternal Age Effect
- (2009) Song-Ro Yoon et al. PLoS Genetics
- Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
- (2008) M. Kimura et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Advanced Parental Age and the Risk of Autism Spectrum Disorder
- (2008) M. S. Durkin et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Advancing Paternal Age and Bipolar Disorder
- (2008) Emma M. Frans et al. ARCHIVES OF GENERAL PSYCHIATRY
- What would the brain look like in Angelman syndrome?
- (2008) Bernard Dan et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Sperm head morphology is related to high deoxyribonucleic acid stainability assessed by sperm chromatin structure assay
- (2008) Armand Zini et al. FERTILITY AND STERILITY
- Deoxyribonucleic acid repair and apoptosis in testicular germ cells of aging fertile men: the role of the poly(adenosine diphosphate-ribosyl)ation pathway
- (2008) Moetaz M. El-Domyati et al. FERTILITY AND STERILITY
- Statement on guidance for genetic counseling in advanced paternal age
- (2008) Helga V Toriello et al. GENETICS IN MEDICINE
- The aetiology of sperm protamine abnormalities and their potential impact on the sperm epigenome
- (2008) Douglas T. Carrell et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Hypothalamic-Pituitary-Testicular Axis Disruptions in Older Men Are Differentially Linked to Age and Modifiable Risk Factors: The European Male Aging Study
- (2008) Frederick C. W. Wu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Strong association of de novo copy number mutations with sporadic schizophrenia
- (2008) Bin Xu et al. NATURE GENETICS
- Telomeres and Aging
- (2008) Geraldine Aubert et al. PHYSIOLOGICAL REVIEWS
- Offspring's Leukocyte Telomere Length, Paternal Age, and Telomere Elongation in Sperm
- (2008) Masayuki Kimura et al. PLoS Genetics
- Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles
- (2007) John L. Frattarelli et al. FERTILITY AND STERILITY
- Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?
- (2007) John A. Collins et al. FERTILITY AND STERILITY
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