Article
Chemistry, Physical
Marcin Lemanowicz, Justyna Chrzanowska, Milena Kotek, Anna Mielanczyk, Maria Kupczak, Daria Niewolik, Anna Korytkowska-Walach, Olesya Klymenko, Alicja Kocur, Dorota Neugebauer
Summary: This study proposed a new method using stimuli-responsive star polymer for crystallization to obtain hollow crystals. The importance of the polymer's phase transition occurrence in the crystal growth process was demonstrated and monitored through absorbance readings and nucleation energetic effects analysis. It was suggested that hydrophobic particles created from polymeric aggregates served as templates for hollow crystal formation.
Article
Polymer Science
Jianhao He, Wenjie Zhang, Chunna Lv, Ruyi Chen, Linan Wang, Yudong Wang, Xiangcheng Pan
Summary: Thermo and pH-responsive star-like block copolymers were synthesized via photoinduced atom transfer radical polymerization with controlled molecular weight and low dispersity using a low ppm level of CuBr2 /tris[2-(dimethylamino)ethyl]amine (Me6TREN) complex. The polymers exhibit both lower critical solution temperature (LCST) transition in water and upper critical solution temperature (UCST) transition in ethanol, with UCST decreasing and LCST increasing based on the composition of side chains and pH in water. These polymers have great biocompatibility, mild phase transition temperature, and adjustable LCST with pH in organisms, making them potential candidates for pH-responsive and thermosensitive applications and as nanoreactors for inorganic nanoparticles growth.
Article
Polymer Science
Hanieh Mardani, Hossein Roghani-Mamaqani, Sina Shahi, Mehdi Salami-Kalajahi
Summary: Stimuli-responsive block copolymers containing light-responsive coumarin moieties were synthesized and used for pH detection through aggregation-induced fluorescence emission intensification mechanism. The micellar structure of self-assembled copolymer chains in aqueous media was confirmed by nuclear magnetic resonance spectroscopy. Dimerization kinetics of the coumarin moieties in micellar assemblies were investigated at different pH values, showing the potential for fluorescence chemosensing of pH.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Song Zhang, Jia Lv, Peng Gao, Qiuyu Feng, Hui Wang, Yiyun Cheng
Summary: This study presented a dendrimer engineered with a high density of 4-diethylaminophenyl groups on the surface, which could efficiently assemble with cargo proteins in serum solutions, enabling intracellular protein delivery. The dendrimer exhibited pH-responsive disassembly behavior after cell internalization, successfully delivering various cargo proteins into living cells with maintained bioactivity. This provides a convenient and efficient strategy for designing polymers with high serum-tolerance in cytosolic protein delivery.
Article
Chemistry, Analytical
Sevketcan Sarikaya, Frank Gardea, Jeffrey T. Auletta, Jamshid Kavosi, Alex Langrock, David M. Mackie, Mohammad Naraghi
Summary: Polymeric artificial muscles offer high actuation stroke and lightweight nature, but many rely on large temperature changes which may cause polymer degradation. This study explores athermal pH-responsive artificial muscles made of aligned and coiled fibers to amplify actuation stroke and work capacity. The coiled pH-responsive fibers show significant improvements in contractive actuation stroke and work capacity compared to their aligned counterparts.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Chaolei Hu, Yimeng Sun, Gil van Wissen, Yitong Peng, Andrij Pich
Summary: In this study, visible light- and temperature-responsive poly(N-vinylcaprolactam) microgels decorated by donor-acceptor Stenhouse adducts (DASAs) were synthesized for the first time using a robust and straightforward post-modification synthesis route. The microgels exhibited homogeneous distributions and temperature responsiveness in aqueous solutions. The photoswitching behaviors of the microgels in different solvents were systematically investigated, and their size in aqueous solutions could be modulated by visible light irradiation. Moreover, the microgels showed potential application in the photostimulated delivery of hydrophobic drugs.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Physical
Jonathan Miras, Chao Liu, Eva Blomberg, Esben Thormann, Susana Vilchez, Jordi Esquena
Summary: Crosslinked chitosan-based nanofilms prepared with the nontoxic reagent genipin showed pH-responsive behavior, swelling at pH 3 and shrinking at pH 6, with reversible changes between these two pH values. The wettability of the nanofilms decreased with increased crosslinking. Quartz crystal microbalance with dissipation (QCM-D) and atomic force microscopy (AFM) were used to study the swelling capacity and elastic properties of the nanofilms, showing irreversible changes at pH 9. AFM results also demonstrated an increase in elastic modulus from approximately 500 MPa at pH 3 to around 700 MPa at pH 6.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Biotechnology & Applied Microbiology
Fan Li, Yan Liang, Miaochen Wang, Xing Xu, Fen Zhao, Xu Wang, Yong Sun, Wantao Chen
Summary: The pH cascade-responsive micellar nanoplatform with nucleus-targeted ability effectively combines synergistic chemo-photodynamic therapy for cancer treatment. The novel multifunctional nanoplatform demonstrates high anticancer efficacy both in vitro and in vivo, making it a promising candidate for synergistic anticancer therapy.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Ruonan Wu, Yuhan Yan, Xingxing Li, Yebang Tan
Summary: In this study, S-PHEDM star block copolymers with pH-responsive properties were synthesized for the controllable reduction of heavy oil viscosity. The properties of the star polymers were characterized, and the aggregation behavior and oil/water interfacial properties were studied. The cyclic regulation of emulsion stability was achieved by adjusting the pH values, providing a new idea for enhancing efficiency during heavy oil recovery.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Multidisciplinary Sciences
Karishma Tiwari, Solagna Modak, Pulak Sarkar, Santanu Ray, Vasista Adupa, K. Anki Reddy, Sumit Kumar Pramanik, Amitava Das, Santanu Karan
Summary: This article reports a method for the room temperature synthesis of ultrathin polyimine nanofilms using transition metal ion catalysts. The membranes exhibit high water permeance, high rejection for certain molecules, and low rejection for others, making them efficient for molecular separation.
Article
Engineering, Chemical
Johanne Pirkin-Benameur, Denis Bouyer, Damien Quemener
Summary: Soft-matter materials research has made significant progress, introducing self-oscillating materials that utilize chemical oscillators to control pH-sensitive polymer chain movements, resulting in continuous pore-size oscillation. The functionalization of commercial membranes with polyethersulfone allows for pore size oscillation, as confirmed by water permeation analysis.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Review
Oncology
Shunli Chu, Xiaolu Shi, Ye Tian, Fengxiang Gao
Summary: The complexity of the tumor microenvironment can be overcome by using pH-responsive polymers for targeted drug delivery, improving treatment efficacy and reducing adverse reactions.
FRONTIERS IN ONCOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yan Qin, Jianguo Yi, Yue Zhang
Summary: The coupling of structurally and functionally controllable polymers with biologically active peptide materials has led to significant research progress in the field of polymers. In this study, a pH-responsive hyperbranched polymer hPDPA was prepared by combining ATRP with SCVP using a three-component reaction of Passerini. The pH-responsive polymer peptide hybrids hPDPA/PArg/HA were obtained, and they could self-assemble into vesicles with narrow dispersion and nanoscale dimensions. When used as drug carriers, they showed significant inhibitory effects on cancer cells through the synergistic therapy based on ROS and NO.
Article
Pharmacology & Pharmacy
Marzieh Sajadi Bami, Mohammad Amin Raeisi Estabragh, Payam Khazaeli, Mandana Ohadi, Gholamreza Dehghannoudeh
Summary: This review examines recent studies on pH-responsive drug delivery systems (DDS) synthesis, properties, mechanisms, and applications. pH-sensitive DDSs deliver drugs at the precise time required by the disease's pathophysiology, improving therapeutic effectiveness and patient compliance. pH-sensitive polymer systems combined with nanotechnology offer a promising alternative to traditional targeting systems, addressing challenges such as non-specific tissue distribution, decreased drug effectiveness, and systemic side effects.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Polymer Science
Carolin Naas, Ulrich Scheler, Uwe Lappan
Summary: The growth and mobility of polyelectrolyte multilayers can be influenced by adjusting the pH value during preparation. Changes in pH lead to non-linear growth behavior and affect the formation and properties of the multilayers.
Article
Polymer Science
Antonina Simakova, Saadyah Averick, Arman Moini Jazani, Krzysztof Matyjaszewski
Summary: This article reports a method for preparing cationic nanogels by atom transfer radical polymerization under inverse microemulsion conditions. The use of a hydrophilic inimer prevents the growth of droplets during polymerization. The surface functionality of the nanogels can be modulated by applying different reactive surfactants or grafting hydrophilic shells. The synthesized cationic nanogels are biocompatible and have a high complexation ability for plasmid DNA.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2023)
Article
Biophysics
Muhit Rana, Tugba Yilmaz, Shirli Cohen, Sinem Beyhan, Avni A. Argun
Summary: Fungal infections pose a significant health concern, especially in immunocompromised population, and a rapid and accurate diagnostic method is needed to improve patient prognosis. In this study, we developed a cost-effective nucleic acid sensor that can detect histoplasmosis-causing fungal genes in whole blood or bronchoalveolar lavage samples earlier than current methods. The sensor uses immobilized nucleic acid probes to directly and label-free detect the presence of specific fungal genes through electrochemical analysis. It provides ultra-sensitive detection of DNA molecules with a limit of detection down to 100 aM, and the turnaround time for sample to result is less than 90 minutes, which is significantly faster than the current clinical procedure.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Entomology
Xinan Li, Saige Zhu, Qiuchi Li, Yulin Sun, Yanbo Wang, Xujun Tian, Xiao Ran, Xiangrui Li, Yunhui Zhang, Haifeng Gao, Xun Zhu
Summary: This study found a highly sulfoxaflor-resistant population of wheat aphids, which also exhibited moderate resistance to two pyrethroid insecticides and low resistance to another insecticide. However, this resistance was accompanied by severely adverse biological fitness.
Article
Agronomy
Qiuchi Li, Xinan Li, Yulin Sun, Xujun Tian, Saige Zhu, Yanbo Wang, Haifeng Gao, Caihua Shi, Xun Zhu
Summary: By comparing the transcriptomes of sensitive and resistant strains of Rhopalosiphum padi to beta-cypermethrin, this study elucidates the mechanisms and genetic basis of resistance. The results show that resistance to beta-cypermethrin is associated with cuticle proteins and detoxification metabolic processes. These findings are significant for further research on the complex mechanism of resistance to beta-cypermethrin in R. padi and other wheat aphids.
Article
Engineering, Environmental
Quanhui Ye, Xiuyu Jin, Baotong Zhu, Haifeng Gao, Na Wei
Summary: In this study, a new biosorbent (MNPLanM) was developed by immobilizing Lanmodulin-SpyCatcher on the surface of SpyTag-functionalized magnetic nanoparticles (MNPs) for selective separation and recovery of rare earth elements (REEs) from waste streams. The biosorbent exhibited high adsorption activity and fast kinetics, and the adsorbed REEs could be efficiently desorbed. MNPLanM selectively adsorbed REEs in the presence of non-REEs and showed high stability after multiple adsorption-desorption cycles. Furthermore, MNPLanM effectively concentrated REEs from low-grade feedstocks, achieving a significant increase in REE purity.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Mateusz Olszewski, Xiaolei Hu, Ting-Chih Lin, Krzysztof Matyjaszewski, Natalia Lebedeva, Philip Taylor
Summary: Star polymers were synthesized via ARGET ATRP and used as effective stabilizers for Pickering emulsions. The interfacial properties of PEO stars adsorbed at oil-water interfaces were investigated using interfacial tension and interfacial rheology. The results offer important insights into the interfacial rheology of PEO star polymers in the context of their application as stabilizers for Pickering emulsions.
Article
Polymer Science
Kriti Kapil, Arman Moini Jazani, Grzegorz Szczepaniak, Hironobu Murata, Mateusz Olszewski, Krzysztof Matyjaszewski
Summary: Photoinduced ATRP techniques using green light and dual catalysis have been developed for efficient and controlled polymerization. This method allows rapid synthesis of well-defined polymers without the need for deoxygenation, overcoming the limitations of UV light-induced polymerization. The system also enables temporal control and synthesis of various hydrophilic acrylate monomers.
Article
Polymer Science
Guanyi Hou, Yingxue Hao, Ruifeng Jiang, Sai Li, Yonglai Lu, Jun Liu, Liqun Zhang, Krzysztof Matyjaszewski
Summary: The rapidly developing aerospace industry has a severe requirement for rubber components utilized for spacecraft, especially the resistance to extreme temperature differences because of the complex space environment. However, it is difficult to increase the service temperature range of the existing elastomeric materials based on traditional methods. By introducing a new type of long-side chain siloxane, a novel silicone elastomer with an unprecedented wide temperature range (-149-400°C) is designed, which does not introduce other heteroatoms.
Article
Polymer Science
Yi Wang, Francesca Lorandi, Marco Fantin, Krzysztof Matyjaszewski
Summary: Polymerizations in aqueous dispersed media benefit from good heat transfer, low viscosity, low content of volatile compounds, and established industrial use. The implementation of ATRP in dispersed media has highlighted the possibility of achieving improved livingness and producing a variety of macromolecular architectures. ATRP techniques employing low-ppm catalyst loadings have enabled access to a larger variety of polymer architectures and functional polymer particles, which have found applications in molecular recognition, drug delivery, bio-quantification, and advanced coatings.
Article
Chemistry, Multidisciplinary
Jaepil Jeong, So Young An, Xiaolei Hu, Yuqi Zhao, Rongguan Yin, Grzegorz Szczepaniak, Hironobu Murata, Subha R. Das, Krzysztof Matyjaszewski
Summary: This study presents an approach to convert biomass RNA into an acrylic crosslinker by acyl imidazole chemistry, allowing for the fabrication of materials with tunable properties. It also explores reversible-deactivation radical polymerization methods and metallization of the biomass RNA-based material, expanding the opportunities in biomass-based biomaterial fabrication.
Article
Polymer Science
Julian Sobieski, Sajjad Dadashi Silab, Lucas Thevenin, Krzysztof Matyjaszewski, Christophe Fliedel, Rinaldo Poli
Summary: The termination processes of the tertiary carbomethoxyisopropylradical, (COOMe)Me2C & BULL;, were investigated by H-1 NMR. The investigation assessed the contributions of the Cu-I/L-catalyzed radical termination (CRT) and the reductive radical termination (RRT) to the spontaneous bimolecular radical terminations (RT). It also reassessed the product distribution for the RT of the diffused and caged radicals obtained from the thermal activation of V-601.
Article
Polymer Science
Krzysztof Jerczynski, Julita Muszynska, Gokhan Demirci, Onur Cetinkaya, Paulina Filipczak, Grzegorz Nowaczyk, Jaroslaw Grobelny, Krzysztof Matyjaszewski, Marcin Kozanecki, Joanna Pietrasik
Summary: This work reports on the efficient performance of hybrid particles with silver nanoparticles distributed within single polymer molecules as Surface Enhanced Raman Scattering (SERS) supports. Through controlled synthesis methods and structure parameters of polymer templates, the researchers successfully synthesized hybrid particles with star-like topology and achieved stable detection of analytes at nanomolar level.
Article
Polymer Science
Rongguan Yin, Yuqi Zhao, Jaepil Jeong, Jirameth Tarnsangpradit, Tong Liu, So Young An, Yue Zhai, Xiaolei Hu, Michael R. Bockstaller, Krzysztof Matyjaszewski
Summary: Gradient copolymer brush nanoparticles with different compositional ratios were synthesized from surface-modified silica nanoparticles, and they demonstrated better mechanical properties and uniform microstructures.
Article
Chemistry, Multidisciplinary
Izabela Zaborniak, Martyna Korbecka, Zuzanna Michno, Pawel Chmielarz, Krzysztof Matyjaszewski
Summary: In this study, a high molecular weight water-soluble polymer was synthesized through polymerization in a vegetable oil-based inverse emulsion, resulting in low dispersity and high molecular weight. This approach offers advantages in terms of environmental friendliness and can replace toxic organic solvents.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Kostas Parkatzidis, Nghia P. Truong, Krzysztof Matyjaszewski, Athina Anastasaki
Summary: A photocatalytic ATRP depolymerization method is introduced, which lowers the reaction temperature and enables temporal control, achieving high monomer recovery and end-group fidelity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
