Article
Materials Science, Ceramics
Hiroyuki Hayashi, Keita Kouzai, Yuta Morimitsu, Isao Tanaka
Summary: Despite extensive research, accurately predicting successful synthesis conditions for new pseudo-binary oxides remains a challenge. This study introduces a synthesis-condition recommender system to efficiently explore a wide chemistry space and successfully discovered two yet-to-be-found pseudo-binary oxides through systematic synthesis experiments.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2022)
Article
Biochemistry & Molecular Biology
Logesh Mahendran, Abimanyu Ravichandran, A. M. Ballamurugan
Summary: Mesoporous silica network nanotubes were successfully fabricated using both organic and inorganic templates, with the phase analysis confirmed by XRD, the functional groups revealed by FTIR, and the tubular morphology analyzed by TEM. The mesoporous nature of each template sample was studied using BET instrument, and the surface area and porous size were calculated successfully for the fabricated silica network nanotubes.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Article
Materials Science, Coatings & Films
F. Khalesi, M. Farhadian, K. Raeissi
Summary: In this work, post-treatment sol-gel methods using acidic and alkaline TEOS solutions were applied to refine the porous network of ZrO2 coating and improve corrosion resistance. The alkaline TEOS solution resulted in the formation of a dense SiO2 interlayer and narrowed pores in the coating, providing the best barrier performance. On the other hand, the acidic TEOS solution mainly formed thin SiO2 layers on the ZrO2 coating surface, leading to poor barrier performance due to electrostatic repulsion forces.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yanting Lyu, Taka-Aki Asoh, Hiroshi Uyama
Summary: By converting recycled cigarette filters into cellulose filters as templates for preparing inorganic oxides, this study demonstrates the potential to produce TiO2 and SiO2 materials with fibrous structures and high surface areas, which can be used for water treatment applications.
Article
Polymer Science
Munguti Peter Muindi, Ji Hae Lee, HaeYong Kweon, Muo Kasina
Summary: This study investigates the extraction, gelation, structural, and cytotoxicity properties of silk sericin (SS) under different conditions, and finds that the concentration of ethanol and temperature have an impact on the properties of SS.
Article
Materials Science, Textiles
Jumei Zhao, Hongtao Zhou, Huizhen Ke, Xueliang Xiao, Qingqing Wang, Quan Feng
Summary: This study involved the fabrication of a PP porous film through melt electrospinning, with a superthin layer of SiO2 gel coating to reduce thermal shrinkage. The SiO2 gel also enhanced the decomposition temperature range and storage modulus of the PP film.
TEXTILE RESEARCH JOURNAL
(2021)
Article
Chemistry, Physical
Jefferson A. Lopes Matias, Evanimek B. Sabino da Silva, Rafael A. Raimundo, Djalma Ribeiro da Silva, Joao B. L. Oliveira, Marco A. Morales
Summary: Nanocrystalline Co sillenite-Co3O4 composites were prepared by combustion and sol-gel methods, and further characterized by various techniques. The sillenite phase exhibited nanostructured with similar content in products from both synthesis methods, showing both ferromagnetic and antiferromagnetic properties.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Physical
Xueting Lian, Jin Gao, Feifei Guo, Ang Qian, Xiaogang Li
Summary: The Sol-gel method was used to prepare a Si-Ti-epoxy organic-inorganic hybrid composite sol, which was cured on the carbon steel surface to form a transparent film with excellent electrochemical protection performance and hydrophobicity. The Si-Ti-epoxy hybrid film has a denser structure, higher impedance modulus, and lower corrosion current density compared to a double-thick epoxy film.
SURFACES AND INTERFACES
(2021)
Article
Materials Science, Ceramics
Zheng-Mao Yang, Han Yan, Jun-Jie Yang, Xiao Li
Summary: This study presents a micromechanical damage model to accurately describe the microstructural damage behaviors of ceramic matrix composites, incorporating matrix-cracking, hierarchical pore nucleation, and fiber breaking mechanisms. Two damage variables are proposed for the damage evolution of matrix and fiber bundles. The model outperforms existing counterparts by capturing microstructural damage mechanisms and allowing quantification of different damage contributions.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Yanhan Fei, Xujie Song, Lanjun Du, Yanchun Wang, Zhiming Du
Summary: This study proposes a method for preparing SiC porous ceramics at lower sintering temperatures using industrial-grade SiC abrasives, and successfully prepares ceramics with macroscopic and microscopic pore structures. This process route reduces production costs and simplifies the production process.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Lidia Resende Oliveira, Eduardo Jose Nassar, Hernane da Silva Barud, Jhonatan Miguel Silva, Lucas Alonso Rocha
Summary: Organic-inorganic composites have many potential commercial applications due to their combination of the chemical and thermal stability of inorganic oxides and the processability and flexibility of organic compounds and polymers.
Article
Chemistry, Physical
G. S. Zakharova, L. Singer, Z. A. Fattakhova, S. Wegener, E. Thauer, Q. Zhu, E. Shalaeva, R. Klingeler
Summary: MoO2/C composites were fabricated for the first time using tartaric acid/glucose-assisted sol-gel method and post-annealing at 500 degrees C in N-2 flow. The composites exhibit low crystallinity and small grain size, leading to good electrochemical performance. The adoption of glucose as carbon source effectively increases the carbon content in the composites, resulting in competitive electrochemical capacity.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Nanoscience & Nanotechnology
Maximiliano Jesus Jara Fornerod, Alberto Alvarez-Fernandez, Eric R. Williams, Maximilian W. A. Skoda, Beatriz Prieto-Simon, Nicolas H. Voelcker, Morgan Stefik, Marc-Olivier Coppens, Stefan Guldin
Summary: Mesoporous thin films are widely used for their high surface area and efficient mass and charge transport properties. A two-step calcination process can reduce film contraction and enhance structural control, resulting in mesoporous films with higher porosity and larger pores. These films exhibit favorable characteristics for mass transport of large molecules.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Yanmeng Guo, Hang Li, Bo Li, Shizhuo Su, Xin Zhong, Derui Kong, Yifan Chen, Yujie Song
Summary: In this study, organic-inorganic composites F70-TiO2 were designed and constructed to become an optical-functional photocatalyst. The optimized composition of F70-TiO2(1:15) demonstrated high photocatalytic activity for the conversion of benzylamine to N-benzylidene benzylamine under visible light irradiation. The introduction of fullerene derivatives into anatase TiO2 greatly enhanced the sunlight utilization and promoted the charge separation and transfer.
Article
Construction & Building Technology
Barbara Ferreira, Sara Sousa, Rui P. C. L. Sousa, Susana P. G. Costa, M. Manuela M. Raposo, Pier Parpot, Artur J. M. Valente, Rui F. P. Pereira, Rita B. Figueira
Summary: This work reports the synthesis of organic-inorganic hybrid membranes for potential optical fibre sensors for pH monitoring of concrete and reinforced concrete structures. The membranes were successfully obtained and showed promising results in simulated concrete pore solutions.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Engineering, Biomedical
Lucia F. Santos, Sonia G. Patricio, Ana Sofia Silva, Joao F. Mano
Summary: This article introduces a method of combining microfabrication platform with magnetic tissue engineering to successfully construct microtissues with complex architecture. By using cells as building units, it is possible to create tissues with multiscale and multifunctional properties, which has significant clinical relevance.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Sara C. Santos, Catarina A. Custodio, Joao F. Mano
Summary: This study introduces a novel human protein-derived porous scaffold produced from platelet lysates, which serves as a platform for xeno-free 3D cell culture. The results show that the scaffold has tunable morphology and mechanical properties, making it suitable for human cell culture without the need for animal-derived supplements.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Mehrzad Zargarzadeh, A. Sofia Silva, Claudia Nunes, Manuel A. Coimbra, Catarina A. Custodio, Joao F. Mano
Summary: In this study, a cell culture support system using enzymes immobilized in hydrogels was developed to generate glucose in situ from hydrogel degradation, promoting cell survival and tissue growth. The laminaran-based hydrogels provided glucose for metabolic activity in 3D cell culture, showing high potential in cell survival compared to native cell-laden laminaran hydrogels. This self-feeding hydrogel system opens up possibilities for applications in tissue regeneration, biofactories, disease models, and cell delivery systems.
MATERIALS HORIZONS
(2022)
Review
Chemistry, Multidisciplinary
Isabel M. Bjorge, Clara R. Correia, Joao F. Mano
Summary: This article highlights the importance of geometry and topography in actively regulating interactions between cells and the extracellular matrix, focusing on the design of 3D microcarriers with unique geometries and surface topographical cues. By modulating these structures, downstream signaling can be activated to control cell morphology, proliferation, and differentiation, contributing to achieving a functional histoarchitecture.
MATERIALS HORIZONS
(2022)
Article
Nanoscience & Nanotechnology
Isabel M. Bjorge, Barbara M. de Sousa, Sonia G. Patricio, Ana Sofia Silva, Liebert P. Nogueira, Lucia F. Santos, Sandra Vieira, Havard J. Haugen, Clara R. Correia, Joao F. Mano
Summary: A modular and hierarchical tissue-engineering strategy is proposed to fabricate vascularized large-scale constructs. The strategy promotes prevascularization and autonomously enhances osteogenesis and construct's mineralization.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Chemistry, Multidisciplinary
Beatriz S. Moura, Maria Monteiro, Luis P. Ferreira, Pedro Lavrador, Vitor M. Gaspar, Joao F. Mano
Summary: The extracellular matrix is crucial for bioinstructing the generation and maturation of human organoids in vitro. This article showcases the recent advances in bioengineering decellularized tissue hydrogels for organoid generation, discussing key design blueprints, characterization methodologies, and extracellular matrix processing toolboxes. The combination of tissue-specific hydrogels and cell engineering technologies may lead to tissue-like physiological responses and further development of organoids as disease surrogates or living therapeutics.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Biomedical
Maria Monteiro, Marta Rocha, Vitor M. Gaspar, Joao F. Mano
Summary: In this study, bioengineering pancreatic cancer models that mimic the tumor microenvironment using in vitro platforms was highly appreciated. These cancer-on-a-bead models exhibit biomimetic multicompartmentalization and tunable integration of cancer-associated stromal elements, recapitulating the signatures of human pancreatic tumors. The models also display increased drug resistance compared to their reductionistic counterparts.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Cell Biology
Daniela S. C. Bispo, Lenka Michalkova, Marlene Correia, Catarina S. H. Jesus, Iola F. Duarte, Brian J. Goodfellow, Mariana B. Oliveira, Joao F. Mano, Ana M. Gil
Summary: This study provides the first comprehensive characterization of the lipidome and exometabolome during osteogenic differentiation of human adipose tissue stem cells (hAMSCs) using NMR spectroscopy. Lipid changes primarily occur between days 1 and 7, followed by stabilization. The findings shed light on the mechanisms involved in membrane remodeling, antioxidant defense, protein synthesis, and energy metabolism during hAMSC osteogenic differentiation.
Article
Engineering, Mechanical
P. Pinto, A. Carvalho, F. S. Silva, J. R. Gomes, S. Madeira, O. Carvalho
Summary: The aim of this study was to evaluate the toothbrush abrasion resistance of four restorative dental CAD/CAM materials available on the market. The results showed that the surface characteristics of all tested materials, except zirconia, were modified by toothbrushing. Polymer was the most susceptible material to toothbrushing wear, while zirconia demonstrated significantly higher resistance to abrasion compared to other materials.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Engineering, Biomedical
Catharina Husteden, Yazmin A. Brito Barrera, Sophia Tegtmeyer, Joao Borges, Julia Giselbrecht, Matthias Menzel, Andreas Langner, Joao F. Mano, Christian E. H. Schmelzer, Christian Woelk, Thomas Groth
Summary: This article presents a gene-activated surface coating strategy for designing smart biomaterials for bone tissue engineering. The thin-film coating is made of polyelectrolyte multilayers composed of collagen I and chondroitin sulfate, and further functionalized with DNA/lipid-nanoparticles. The successful formation of the thin-film, fibrillar structuring of collagen, and homogeneous embedding of lipoplexes is demonstrated. Culturing mesenchymal stem cells on the functionalized multilayer shows excellent attachment, growth, and uptake of cargo like fluorescence-labelled DNA from lipoplexes. Furthermore, the functionalization of the multilayer induces osteogenic differentiation of mesenchymal stem cells.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Materials Science, Multidisciplinary
Joao Rocha Maia, Rita Sobreiro-Almeida, Franck Cleymand, Joao F. Mano
Summary: Three-dimensional printing has emerged as a promising method for biofabrication of tissue engineering constructs, aiming to create tissue/organ replacements for precision medicine. By using human-sourced biomaterials with optimal rheological properties, the best possible scaffolds can be created, enhancing clinical outcomes. This paper provides an overview of current efforts in achieving necessary ink properties for biofabrication and discusses crosslinking strategies. It also explores the state-of-the-art of using human-sourced inks and presents future perspectives on the field.
JOURNAL OF PHYSICS-MATERIALS
(2023)
Article
Mathematics
Pau Urdeitx, Sandra Clara-Trujillo, Jose Luis Gomez Ribelles, Mohamed H. Doweidar
Summary: Bone marrow mechanical conditions are important in multiple myeloma cancer, but the complexity of these conditions hinders effective treatments. Agent-based computational models can help identify the tumor microenvironment. A novel hybrid 3D agent-based model has been developed to study multiple myeloma cells' growth.
Review
Medicine, Research & Experimental
Daniela Patricio, Joana Santiago, Joao F. Mano, Margarida Fardilha
Summary: This article provides an overview of organoid technology and its applications in healthcare and research, with a focus on male reproductive system organoids and other biomaterials. The article also discusses current applications and highlights the research gaps, challenges, and opportunities in the field.
WIRES MECHANISMS OF DISEASE
(2023)
Article
Materials Science, Biomaterials
Adrian Hautmann, Devaki Kedilaya, Sanja Stojanovic, Milena Radenkovic, Christian K. Marx, Stevo Najman, Markus Pietzsch, Joao F. Mano, Thomas Groth
Summary: In this study, free-standing multilayer films (FSF) made of chitosan and alginate were crosslinked to achieve sustained release of growth factors and possessed biocompatibility and antibacterial properties. The films showed potential applications in wound healing.
BIOMATERIALS ADVANCES
(2022)
Meeting Abstract
Cell & Tissue Engineering
Sara Nadine, Clara R. Correia, Joao F. Mano
TISSUE ENGINEERING PART A
(2022)
